From the President

WAY TO GO KINDERVELT!
TOGETHER WE MADE A DIFFERENCE!
We have reached an all time record-breaking year! Congratulations Kindervelt for raising $660,000 for the Division of Critical Care Medicine and the Pediatric Intensive Care Unit (PICU). I’m bursting with excitement and so proud of our very impressive achievement.
 
Many thanks to Linda Deters for organizing a beautiful and memorable evening for our Annual Meeting at Clovernook Country Club. Highlights of the evening include recognizing members for their milestone membership accomplishments and celebrating the 2023 Barbara Fitch Award recipient, Mary Beth Young. Congratulations Mary Beth!
L-R: Cindy Burger, Dr. Maya Dewan, MD, MPH, Charlotte McBrayer, Dr. Matthew Zackoff, MD, MEd.
It's been my pleasure to work with the 2022-2023 Board of Trustees this past year. I now welcome the 2023-2024 Board of Trustees as we move forward into the new fiscal year. We are transitioning into our final year of our four year commitment to the PICU and I can’t wait to see what we can accomplish together.
 
Take some time and check out some of our summer events happening around the city. Kindervelt #49 is hosting a night of comedy at Go Bananas on June 13th and Kindervelt #16 is hosting a golf outing July 10th. Enjoy the summer with family and friends and I look forward to making new Kindervelt memories with all of you.
Your friend in Kindervelt,





Cindy Burger
Kindervelt City President


Cindy Burger
Dr. Maya Dewan
Dr. Matthew Zackhoff
Keith Henize
Annual Meeting
Thank you to all of you for attending the 52nd Annual Meeting at Clovernook Country Club. It was an exciting night as we presented the check to the hospital for $660,000. It is such a privilege to be part of such a great organization that gives endless hours raising money to support the Division of Critical Care Medicine and the Pediatric Intensive Care Unit of Cincinnati Children’s Hospital Medical Center. You are the Best!!

A very special thank you to Dr. Matthew Zackoff for volunteering to speak at this year’s Annual Meeting. We value his dedication to the PICU as well as his innovations to prepare staff members for treating the patients in the new critical care building.

A warm and special “thank you!” to Christine Coulter and the staff of Clovernook Country Club for all their special attention to detail to provide such a wonderful atmosphere for our event. The staff truly made my job easier to prepare for the evening.

It goes without saying that we want to thank Keith Henize and Kelly Bollinger for their support and assistance with the many details and preparations needed for the evening. It is so greatly appreciated.

Last but definitely not least, I would like to thank Cindy Burger for her dedication to Kindervelt over the past year as President. I saw first-hand how she devoted endless hours to running the BOT and Leadership meeting, attending group meetings, attending all of the events while keeping a positive attitude and smile through it all. We are lucky to have her for another year!
Dr. Matthew Zachoff
Citywide President, Cindy Burger with Annual Meeting Chair, Linda Deters
Linda Deters
Annual Meeting Chair
If you were unable to attend, or would like to see the reveal again, Click HERE.
50 year members Lin Wolf #16 & #45, Nancy Groves-VanBuskirk #29.
Cindy Burger, Citywide President 2022-24 with Suzanne Nemeth, Incoming President for 2024-26
2023 Barbara Fitch winner Mary Beth Young with Elizabeth Young, Craig Young, Mary Beth, Steven Young, Michael Young, Kelsey Biller.
10 Year members, Joyce Warner #16, Catherine Fessel-Smith #56, Sarah Sullivan #76.
20 Year member, Mary Lively #30 with Katrina Smith- Past President.
30 year members Theresa Skogland #16, Carol Zacher #77.
All Annual Meeting images have links to enlarge.
There are lots of wonderful photos from the annual meeting.
If you would like to check them out, click HERE!
Upcoming Events
All flyers are downloadable, just click on the image
Let's Laugh for Kid's Sake!
Join KV #49 on
Tuesday, June 13th
Go Bananas Comedy Club
8410 Market Place Lane, Cincinnati

$25. Per person for a great night of laughs.
Drinks & appetizers available for purchase.
KV #16 Golf Outing
July 10th
Clovernook Country Club
KV #16 Golf Ball Drop!
Golf Ball Drop / Split the Pot 
You don’t have to golf or be present to win! Purchase golf balls for chances to win split the pot. 
Be on the Lookout!
June 13th - KV #49 Go Bananas Comedy Night
July 10th - KV #16 Golf Outing
September 22nd - KV #16 Bunco
October - KV Krafts at Burger Farm
November 4th - KV Krafts Seton High School
November 10th - City Wide Fall Event - Monte Carlo Night
November 15th - KV Krafts at CCHMC

The Kindervelt Store
The Kindervelt Shopify store will be closed effective June 1st, 2023. Thank you to everyone who supported this effort. All store items will be returned to the group which provided them. Returns will be made over the summer.
Kindervelt Krafts Let’s enjoy the summer sitting by the pool keeping our hands busy Krafting! When the fall arrives we will have so many beautiful items to sell at our Kraft Shows. Keep those krafts coming and have fun in the sun! We will have the gift card station again this year so start asking for gift card donations, $10 preferred, larger is fine too! Questions, contact Bonnie at bonniehueneman@gmail.com

KV #19 was able to present about $90,000 for the year to the citywide group. They take a break during the summer but are excited for the new year. KV 19 had one of the largest group of new members last fall and can't wait to see who will join this year! 
KV #22 celebrated the end of the season at the home of Marilyn Jacoby. We catered in Mazunte while toasting our incoming board. Thanks to all for a great year!
L-R Gale McLaughlin, Kim Lucken and Sue Crosby
L-R: Deb Clerc, Lis Faber, Perri Schenker, Kate Moody and Sally Chase
KV #78 This is the year of knee replacements for our group, 2nd quarter to be exact. We are wishing a speedy recovery to Nancy Riedel who had hers May 24th, and best wishes and a speedy recovery to Ruth Wiley on hers, June 5th. Mary Beth Young is well on her way to recovery from hers on April 19th.
KV #16 A Huge Thank You to Linda Deters for all her hard work making our Annual Meeting such a success at Clovernook Country Club. The evening was amazing and, of course, culminated in the Grand Total for the year. Thank you to Cindy and her accomplishments as our KV Citywide President and to all the ladies in KV 16 who have helped and share in this impressive amount!
KV #19 would like to thank their many sponsors for this year's "Run for the Roses." Sponsorship was huge this year. The women of Kindervelt #19 are so happy to have raised around $85,000 during their "Run for the Roses" event this summer. This is a record for the group! 

KV#22 Congratulates & thanks their 2023 -2024 officers who will help lead the group through another great year of fundraising and fellowship! Co-Presidents – Sue Crosby and Bonnie Finn, Treasurer – Kathy Roth, Secretary – Marla Gross, Publicity – Amy Rosenberg, Sunshine – Lis Faber

KV #78 Would like to thank our officers from 2022-23 for stepping up and and agreeing to stay on for 2023-24.
KV #16 Congratulates Lin Wolf on her 50 year Kindervelt recognition. She served on 3 KV BOTs, 
Steering Committees for KinderKlaus Markt, Tennithon, KV Krafts mostly as Treasurer, group officer positions for KV #16. She was also the second Barb Fitch Award winner in 2006. We also want to congratulate Terri Skogland for 30 years and Joyce Warner for 10 years. Without you women, Kindervelt would not be the great organization it is in Greater Cincinnati. Thank you for all those hours of volunteering and dedication to such a worthy cause!

KV #29 Congratulates two more of its members who achieved the 50 year recognition. 
Mary Austin, who served on 4 KV BOTs during the late 70s and early 80s as well as a member of several KinderKlaus Markt (KKM) Steering committees and was the 1984 KKM Chair. She was very much involved on the 1985-1987 Kindervelt Committee for the 1987 World Figure Skating Championships held here in Cincinnati.
Nancy Groves VanBuskirk has served on 9 KV BOTs, was the creator of the KKM Storefronts, was the 1977 KKM Chair, sat on several city wide committees, held several group officer positions in both KV #6 and KV #29, and was the 2008 Barb Fitch Award winner.
But we don't want to forget Lynda Thomas, who passed away this January just missing her 50 years in KV. She was a charter member of KV #5 and then joined the Blue Ash KV group before Joining KV #29. She also was on the KV 1977/78 BOT as Member-at-Large, and a very generous donor to Kindervelt.
KV #77 Would like to congratulate Alex Nolte. Her business, The Goddard School (West Chester/Hamilton), was one of four recipients of the Goddard Brand Ambassador Award; there are 600 Goddard Schools across the country. Our group couldn’t be more proud of her. She shared “it has been a few hard years navigating a pandemic, the great resignation and many other obstacles, but I never forget our number one priority is always the children under our care!”
Goddard Brand Ambassador - Alex Nolte
Jewelry winner - Judy Williams
KV #77 Would like to congratulate member Judy Williams who was the winner of the Jewelry Key station at our luncheon/fashion show last month. Thanks again to Bill Welling’s Fine Jewelry of West Chester for donating to our event.

KV #78 Sends a huge congratulations to our own Mary Beth Young for winning the prestigious Barbara Fitch Award! We love you and appreciate all you do! We would also like to congratulate Nancy Riedel on achieving her 50 year recognition.
KV #22 - With deep sadness and sincere condolences goes to Shelley Reddy and her family on the passing her daughter Rachael at the age of 28. Rachael’s joy and light will be missed by many. At the time of her passing, she was living at St. Joseph Home and throughout the years received warm and exceptional care from the staff there, as well as Cincinnati Children’s Hospital.
June 4th - Vivian Cosio #77
June 7th - Janice Miller #68
June 8th - Kim Krause #19
June 10th - Sheila Maxwell #78
June 12th - Diana Scrimizzi #12
June 14th - Sally Westendorf #68
June 19th - Sally Chase #22
June 22nd - Nancy Riedel #78
June 22nd - Stephanie Janseen #22
June 25th - Kim Lucken #22
June 28th - Kim Tepe #12
July 4th - Debbie Eilerman #68
July 5th - Audrey Brown #22
July 6th - Ruth Wiley #78
July 12th - Glenda DeJesus #12
July 20th - Tina Borders #19
July 22nd - Lillie Moss #77
July 27th - Gale Beckett #19
July 28th - Phiroza Setna #19
July 28th - Gina Arens #19
July 29th - Nancy Morton #78
From the PICU - Giving Critically Ill Children with Sepsis the
Best Possible Antibiotic Therapy
Kelli Paice, MD*+
Katie Pavia, MD*+
Sonya Tang Girdwood, MD, PhD*@
Jennifer Kaplan, MD, MS+
Divisions of Critical Care Medicine+, Clinical Pharmacology* and Hospital Medicine@
When sick children with suspected infections arrive in the Pediatric Intensive Care Unit (PICU), the key therapy we use to treat them is broad-spectrum antibiotics. The most common antibiotics used to treat children are “beta-lactams,” which kill bacteria by targeting their cell wall. Beta-lactam antibiotics include familiar names like penicillin, but also critically important intravenous (“IV”) drugs used in the hospital like ceftriaxone, cefepime, piperacillin-tazobactam, and meropenem. A common mantra in the PICU is that the earlier antibiotics are started, the better! However, perhaps just as importantly, we need to be sure the doses we use lead to concentrations that maximize bacterial killing and minimize unnecessary toxicity to the child.

Physicians and researchers at Cincinnati Children’s are leading the way in studying the pharmacokinetics of beta-lactams in the pediatric ICU. Pharmacokinetics, or “PK” refers to how medications are absorbed, dispersed, metabolized, and cleared in the body. The changes in physiology that we see in critically ill children (lower blood pressure, higher heart rates, fever, need for respiratory support, or kidney injury, as just a few examples) mean that the same antibiotic dose can yield very different antibiotic concentrations compared to what might be measured in non-critically ill children. Further, when medications are studied to create packaging labels with recommendations for dose amount and frequency, critically ill children are not the population used in the studies to make these recommendations. Despite these concerns, levels of beta-lactam antibiotics are not routinely measured, making the assurance of effective dosing all the more unknown. Our current practice using a standard “one-size-fits-all” approach, in which the same dose and dosing intervals are prescribed for all patients, may not provide the best care to patients in the PICU.

For these reasons, our team is working to optimize antibiotic treatment through via multiple aims: 1. understand how to ensure adequate antibiotic concentrations in critically ill children; 2. recognize and avoid beta-lactam associated toxicities; and 3. determine when antibiotic dosing should be adjusted from the standard weight-based strategy. Projects underway include developing models to predict ceftriaxone and piperacillin-tazobactam levels in critically ill children; assessing how fluids given during early severe sepsis therapy affect meropenem concentrations; and defining cefepime-associated neurotoxicity and understanding which patients are most at risk.

Our team includes Kelli Paice, MD and Katie Pavia, MD, two 3rd year critical care and clinical pharmacology fellows (both have been awarded National Institutes of Health T32 fellowships in Pediatric Clinical Pharmacology and will be staying at CCHMC for an additional year devoted to research); Sonya Tang Girdwood, MD, PhD from the Divisions of Hospital Medicine and Clinical Pharmacology; and Jennifer Kaplan, MD, MS who is the Director of Clinical Research for the Division of Critical Care Medicine.

In the coming year we will be conducting multiple additional research studies in the PICU with the help of our clinical research coordinators, clinical research nurses, and colleagues from the Division of Clinical Pharmacology. Much of our work makes use of “opportunistic sampling”, where we obtain blood left over from labs collected for use in clinical care and measure the antibiotic concentrations in the remaining sample. This technique helps overcome one of the classic challenges of research in pediatric patients – avoiding a high burden of “pokes” and blood loss in our smallest patients. We aim to be one of the first children’s hospitals in the United States to provide in-house β-lactam antibiotic assays and an antibiotic precision dosing service to provide clinicians information on precision dosing of antibiotics. Overall, our team’s goal is to move closer to the ideal of “precision medicine” – where every child can be treated with medicines and procedures that are tailored to their unique physiology, genetics, and clinical situation.