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JANUARY 2025

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Policy Perspectives: Dementia


Dementia diagnoses will increase dramatically over the next years, according to a recent New York Times article. The article discusses new research suggesting the number of people in the United States who develop dementia each year will double over the next 35 years to about one million annually by 2060, with the number of new cases per year among Black Americans tripling. The increase will primarily be due to the growing aging population, as many Americans are living longer than previous generations. Increasing numbers of patients with dementia will also impact how care to these patients is delivered.


Many IHPS faculty research dementia care. Alissa Sideman, PhD, MPH, MA, Alma Hernandez de Jesus, and colleagues have a recent paper sharing the dissemination results of the Care Ecosystem, an effective collaborative care model that bridges medical and social care needs for individuals with dementia.  Michael Steinman, MD, Leah Karliner, MD, MAS, Elena Portacolone, MBA, MPH, PhD, Kristine Yaffe, MD, John Boscardin, PhD, and Krista Harrison, PhD, along with their colleagues look at the use of high-risk medications by adults with cognitive impairment living alone. More than one-fourth of older adults with cognitive impairment live alone; these individuals often lack support for medication management and face a high risk of adverse drug events. The findings in their research findings can inform medication optimization interventions supporting this vulnerable population.

IHPS FACULTY SPOTLIGHT

Erica Farrand, MD


"One thing that interests me right now is the role of AI (artificial intelligence) in both our clinical care models and research and what implications this has for all of us in both the communication and transparency of how AI is already integrating into our clinical care and research pipeline and what we anticipate the future will look like."


Dr. Farrand is an Assistant Professor in the Division of Pulmonary, Critical Care, Sleep, Allergy and Sleep Medicine and affiliated faculty at IHPS. Dr. Farrand's scholarship focuses on defining, assessing and improving the health care quality, safety and outcomes for individuals with interstitial lung disease.

IHPS FOCUS

Catherine Chen, MD


What are you currently working on? I’m conducting a pilot study to assess how well older adults tolerate sedation with oral benzodiazepines as an alternative approach to routine anesthesia care for cataract surgery.


What drew you to work on this? I’ve always been interested in patient safety and healthcare value. The ongoing shortage of anesthesia providers within the context of an aging US population motivates me to try and find alternative sedation options for cataract surgery that help allocate limited anesthesia resources more effectively. While routine anesthesia care has been the standard of care for cataract surgery sedation for decades, technological innovation has made it feasible for cataract surgery to be performed safely under local/topical anesthesia with light intravenous sedation. For selected patients, offering oral sedation for this procedure would potentially allow cataract surgery to be performed without the routine presence of anesthesia-trained clinicians. The demand for all surgical procedures (including cataract surgery) will continue to increase with the aging population, and many procedures cannot be performed without the expertise of anesthesiologists. My goal is to ensure that everyone who needs surgical care can have timely access to critical anesthesia services while preserving safe models of cataract surgery sedation that are acceptable to both patients and ophthalmologists.


What's next? Building on our pilot results, I plan to continue this line of inquiry with a full-scale RCT.

Mara Decker, DrPH


What are you currently working on? I am currently working on several health education projects co-developed with youth. One of the most recent is a study integrating a behavioral health intervention into sports-based programming with colleagues at Soccer without Borders.


What drew you to work on this? Working directly with youth and community-based partners is inspiring and informative. It helps ensure that my research is relevant. For example, when developing “booster” sexual health education with older teens in the Central Valley, the teens really prioritized learning more about healthy relationships and communication.


What's next? We are about to launch an RCT of a fully online sexual health education program for youth in rural communities throughout the US. In some places, this information is no longer taught in schools. We are interested in seeing if the program improves health outcomes as well as learning how to best engage youth in online programming.

Mary Whooley, MD


What are you currently working on?  My work leverages clinical informatics to accelerate the adoption of evidence-based practices that improve the quality of healthcare delivered within the VA's national learning health system.


What drew you to work on this? I like to fix things and optimize efficiency. If I had not gone to medical school, I would have become a systems engineer. Fortunately, the Veterans Health Administration healthcare system provides many opportunities to combine these interests! Our current work focuses on “Learning Health System” (Friedman et al, 2010) projects that identify quality gaps (data to knowledge), implement interventions to address those gaps (knowledge to performance), measure the impact of those interventions on healthcare outcomes (performance to data), and capture that data to identify further improvement opportunities (data to knowledge). During the past decade, for example, my mentees (a) found that guideline-recommended cardiac rehabilitation was vastly underutilized in patients with cardiovascular disease (Park et al, 2017Beatty et al, 2018); (b) designed and implemented a novel home-based program at VA facilities (Rohrbach et al, 2017); (c) quadrupled participation in cardiac rehab (Schopfer et al, 2018; (d) reduced wait time from index event to enrollment by 2 months, with similar outcomes to traditional programs (Schopfer et al, 2020); and (e) demonstrated lower mortality in patients who did versus did not enroll (Krishnamurthi et al, 2023).

 

What's next?  We recently launched a Learning Health System Embedded Scientist Training and Research (LHS E-STAR) Center Scholars Program at UCSF. Our goal is to train the next generation of Learning Health System scientists to improve healthcare delivery using this model.

FRONTLINE FINDINGS

Leah Karliner, MD, MAS, Christina Mangurian, MD, MAS, and colleagues published Depression Treatment After a Positive Depression Screen Result in JAMA Internal Medicine. In this cohort study, moderate rates of initial treatment among patients with elevated depressive symptoms and/or suicidal ideation (SI) were found. Targeted interventions are needed for patients at risk of undertreatment, including patients with SI, African American or Black and Asian patients, and older adults.

Dorie Apollonio, PhD, MPP, and colleagues published Effect of a Minimum Floor Price Law for Tobacco Products on Tobacco Sales in Oakland, California, USA: A Synthetic Difference-In-Differences Analysis in Tobacco Control. In May 2020, Oakland became the most populous city in California to implement a minimum floor price law (MFPL), requiring tobacco retailers to sell cigarettes and cigars at $8 or more per pack/package. Policy enforcement began in August 2020. Oakland’s MFPL produced an aggregate decline in cigarette sales of 15%. MFPLs hold promise as a complement to tobacco taxation for reducing tobacco use, especially in localities that pre-empt local tobacco taxation.

Chuan Mei Lee, MD,MA, Jayme Congdon, MD, MS, and colleagues published Practice-Based Models of Pediatric Mental Health Care

in the Pediatric Clinics of North America. Integrating behavioral health services in pediatric primary care can help address the growing mental health needs of children and adolescents in the US. Given the different approaches for integration, pediatric primary care practices may evaluate the features of each model and considering tailoring it to their unique practice environments.

Brian Anderson, MD, and colleagues published 

Psychedelic Regulation Beyond the Controlled Substances Act: A Three-Dimensional Framework for Characterizing Policy Options in the American Journal of Psychiatry. The growing interest in psychedelics coupled with municipal and state efforts to liberalize psychedelic regulation prompts consideration of a wide and complex range of potential policy options. The researchers propose a three-dimensional framework that contextualizes psychedelic uses by their degree of legality, therapeutic intention, and structure, and briefly reviews current non-federally regulated policy options and how they can be examined through this framework.

Elizabeth Dzeng, PhD, MD, MPH, and colleague, Sarah Rosenwhol-Mack, MD, published The Effects of Individual Ethical Frameworks on Clinician Moral Distress in the Journal of General Internal Medicine. Moral distress is often defined as the inability to act in accordance with one’s ethical beliefs because of institutional or other constraints. Moral distress was more frequently described among physician trainees with a best interest framework than those with an autonomy framework. This finding held true among both US and UK physician trainees. 

More IHPS Faculty Research

MEDIA MENTIONS

Julia Adler-Milstein/A Jay Holmgren:

Researchers: Hospitals Need to Improve Accuracy, Bias Measurement in AI

(Healthcare Innovation)

Leslie Suen:

Microdosing to Quit Fentanyl? New Study Reveals Surprising Challenges

(SciTechDaily)

Tracey Woodruff:

The hidden danger in the air that can cause infertility, colon cancer and lung problems

(Yahoo News)

UPCOMING EVENTS

Intimate Partner Violence Among Birthing People: Rural-Urban Differences and Implications for Safety and Equity

Katy Kozhimmanil, PhD, MPA

Vice Provost for Special Projects at Harvard University, Carol K. Pforzheimer Professor at Harvard Radcliffe Institute

Professor of Public Health Policy at the Harvard T.H. Chan School of Public Health

Harvard University

Intimate Partner Violence Among Birthing People: Rural-Urban Differences and Implications for Safety and Equity


Feb 5, 12 - 1 pm PT

Zoom Here

2025 Chancellor's Health Policy Lecture


Dave Chokshi, MD, MSc

Chair of the Common Health Coalition

Co-Chair of the Health and Political Economy Project

Sternberg Family Professor of Leadership

City College of New York


Mar 12, 2025, 12 - 1 pm PT

UCSF Nancy Friend Pritzker Psychiatry Building Auditorium

675 18th Street, San Francisco

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IHPS has recently begun using LinkedIn. Please follow us at the link below! We will be sharing valuable updates regarding the work the IHPS community is engaged in, insights on current health policy-related matters, and information regarding IHPS-related events regularly. 

IHPS LinkedIn

Philip R. Lee Fellowship Fund

Since its founding 50 years ago, IHPS has been dedicated to training the next generation of leaders in interdisciplinary research to solve our most important health policy issues. In celebration of our 50th anniversary and to honor our founders, Phil Lee and Lew Butler, we established an endowment fund for the Philip R. Lee Fellowship. We hope to continue to keep this fund and our fellowship program robust.

Donate to IHPS

Photo: Kim Felder Rhoads, MD, MS, MPH & Fellow for 2007-2008 with Philip R. Lee, MD, Founder of the Institute for Health Policy Studies

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