UCSF CCMBM Core Services

UCSF CCMBM Core Services Newsletter - August 2024

CCMBM Cores:

Featured Services

The Core Center for Musculoskeletal Biology & Medicine (CCMBM) defines itself

by emphasizing musculoskeletal-specific education and services that are critical to its members but not available elsewhere in the university system.

“The CCMBM allows a platform for postdoctoral fellows to build and move up in their careers. It creates a wonderful environment for camaraderie and open discussion of research as well as a home for international postdoctoral trainees.”

--Thomas Link, MD, PhD, Chief, Musculoskeletal Imaging Section & Clinical Director, Musculoskeletal and Quantitative Imaging Research (MQIR) Group, Department of Radiology and Biomedical Imaging, UCSF

CORE SERVICE UPDATES

LEARN MORE

The Imaging Core provides state-of-the-art, customized image acquisition, reconstruction, and quantitative analysis for pre-clinical (tissue samples and animal models) and in vivo human musculoskeletal research.

The new rates for our most commonly used services are listed below, effective July 1, 2024. CCMBM Early Stage Investigator and Trainee members are eligible to receive a 25% discount on all research recharges. Please note discounts are available until funds are depleted.

Please direct any questions about Imaging Core services to Galateia Kazakia and Victor Cheuy.

0.55T/3T/7T MRI Scan:

$645 per hour

PET-MR Scan:

$900 per hour

Nurse (for contrast or eGFR testing):

$196 per hour

Contrast Agent:

$78 per 20 ml bottle

PET-CT Scan:

$900 per hour

HR-pQCT Scan:

$358 per hour

DXA Scan:

$57 per anatomic site + $41 per visit

Micro PET-CT Scan:

Internal Rate: $118 per hour

External Rate: $149 per hour

RAP FALL 2024 CYCLE RFA

Submission deadline: September 30, 2024, 2:00pm PST

The Resource Allocation Program (RAP), an umbrella consortium of UCSF funders that coordinates multiple intramural research funding opportunities, is now accepting applications for the Fall 2024 Cycle. Review the grant-specific descriptions/instructions for the grant mechanism you are applying, not the funding agency. Funding agencies will select the awardees by choosing the proposals that best fulfill their programmatic goals. Simultaneous consideration of each application by multiple funding agencies enhances funding likelihood.

Grant Review sessions are available to allow investigators to strengthen their proposals for this cycle. Individuals will who sign up will receive 1:1 feedback and/or live panel review with peers as well as coaching from experienced investigators. The following dates are still available:

Thursday, September 5th, 8:30 am - Radiology

Tuesday, September 10th, 10:00 am - SFVAMC Endocrine Unit

Friday, September 13th, 10:00 am - CCMBM Bone Investigator Group

To have your proposal reviewed, please fill out our sign up form. Please apply ASAP to ensure that the committee has time to review your proposal prior to the session date.

Funding results will be available by December 2024. See CCMBM Funding Opportunities for the RFA.

JUNIOR INVESTIGATOR GRANT DEVELOPMENT AWARDS

The Grant Development Award provides funding for a junior CCMBM member to host a meeting (e.g., lunch or dinner) with 1-3 UCSF faculty members who are outside of the trainee’s current lab to:

1) brainstorm/solicit informal feedback on a study idea or research direction

2) learn about the latest methods and techniques used in related fields

3) identify potential collaborators

4) promote inter-disciplinary MSK research

5) expand the trainee’s professional network

If you are not a member, you may concurrently apply for membership while your Grant Development application is being reviewed.

Apply via the online application form today! Contact Noah Bonnheim for questions on this funding opportunity.

CCMBM GRANT REVIEW SESSIONS

The CCMBM would like to help investigators strengthen their grant proposals in advance of any upcoming NIH deadlines. We invite CCMBM members to participate in the Grants Review program to receive 1:1 feedback and/or live panel review with peers as well as coaching from experienced investigators. If you are not a member, you may concurrently join during your grants review period.

Upcoming NIH Cycle III deadlines include:

P Series, T Series, and D Series Grants: September 25, 2024

R18, U18, R25, and C06/UC6 Grants: September 25, 2024

G07, G08, G11, G12, G13, G20, R24, S06, S11, S21, S22, SC1, SC2, SC3, UG1, U10, U19, U24, U2C, U41, U42, U45, U54, and U56 Grants: September 25, 2024

Fill out the sign up form to attend an upcoming session.

CCMBM CORE DISCOUNTS

The Imaging Core is offering service discounts to Early Stage Investigator and Trainee members. The Epidemiology, Biostatistics and Study Design Core is also offering up to 6 hours of free UCSF Clinical and Translational Institute (CTSI) consultation time for all CCMBM members. Please contact each Core to utilize these member discounts.

Please contact Tom Sullivan for eligibility questions.

UPCOMING EVENTS

August 14, 8:00-9:00am PT; Virtual Event

Networking Webinar: Whole Person Research and Coordination Center (Whole Person RCC)

The Networking Webinar will provide applicants with an opportunity to meet and greet with potential partners or collaborators needed to form strong multidisciplinary applicant teams for the Whole Person Research and Coordination Center (Whole Person RCC) U24, RFA-AT-24-010. This is part of the NIH Whole Person Initiative.

Hosted by NCCIH

---

August 14, 10:00am-12:00pm; Virtual Event

Perfecting the Elevator Pitch

You never know who you will meet on a plane, at a conference, or in an elevator. At any moment you should be able to explain your mission statement, research goals or entrepreneurial ideas in a short yet captivating way. This interactive workshop teaches you to clearly articulate your passions so you can take advantage of every opportunity that comes your way.

Hosted by the UCSF Benioff Center for Microbiome Medicine, ImmunoX, and the UCSF Musculoskeletal Center

---

August 14, 12:00-1:30pm; Virtual Event

SpeechSkills Seminar on Projecting Credibility and Confidence

Come learn how to increase your effectiveness and impact during this high-yield seminar from an expert who has shared her work spanning industries all around the globe for over 20 years.

Join via Zoom.

Hosted by the UCSF Academic Senate

---

August 14, 1:00-2:00pm PT; Virtual Event

2024 CSR Summer Trainee Lecture Series

Eva Liu, MD, Associate Director, CSR Histology Core & Assistant Professor of Medicine, Brigham and Women's Hospital/Harvard Medical School

"Vitamin D"

Join via Zoom.

Hosted by the Center for Musculoskeletal Research

---

August 14, 20, 21, 27, 28, 2:00-3:00pm; Mission Bay, CC-151

Data Science Help Desk

Introducing the hybrid Data Science Help Desk, a place to ask your general questions about data science including how to download software or code packages, prep for upcoming data science classes, get started with programming, connect with data science expertise, and more. No appointments required, just walk/drop in!

Join via Zoom.

Hosted by the UCSF Library

---

August 15, 22, 29, 12:00-12:30pm & August 20, 27, 7:00-7:30am; Virtual Event

Compliance Educator Office Hours

Schedule time to meet with an Educator. Bring your coding and documentation concerns. We are here to help you.

Join via Zoom (Tuesdays).

Join via Zoom (Thursdays).

Hosted by the Office of Healthcare Compliance and Privacy

---

August 15, 12:05-1:00pm; Virtual Event

Participant Recruitment Program Office Hours

Join the Participant Recruitment Program (PRP) for monthly office hours, a platform for UCSF researchers and study teams to gain insightful information on services available to help with participant recruitment. These Zoom sessions will cover topics such as EHR Recruitment, Social Media Recruitment, and information on free design and advertising tools, including flyer templates, plain language study descriptions, and more.

Join via Zoom.

Hosted by the UCSF CTSI

---

August 15, 1:00-2:00pm; Mission Bay, Gladstone Institutes, Mahley Auditorium

GICD/CVRI Seminar Series

Nathan Palpant, PhD, Associate Professor, Institute for Molecular Bioscience, University of Queensland

"Linking Genetics to Drug Discovery for Cardiovascular Disease"

Join via Zoom.

Hosted by the Gladstone Institutes

---

August 15, 2:00-4:00pm; Virtual Event

C2C Seminar Series: Fostering Diversity in Clinical Research

This series of seminars will provide high-yield, practical information about designing, funding, and conducting patient-facing oncology trials.

Hosted by the Helen Diller Family Comprehensive Cancer Center

---

August 16, 12:10-1:00pm; Parnassus, CS-0101

Microbiome Ignite Talk

Paul Wilmes, PhD, Full Professor of Luxembourg Centre for Systems Biomedicine, University of Luxembourg

"Systems ecology of the human microbiome in health and disease: from data to mechanism"

Hosted by the UCSF Benioff Center for Microbiome Medicine

---

August 18, 10:00am; Mission Bay, Mariposa Park (Mariposa St. & Owens St.)

UCSF Sarcoma Strong 5K Run + Walk

The UCSF Department of Orthopaedic Surgery is thrilled to announce the annual UCSF Sarcoma Strong 5K Run + Walk, a pivotal event dedicated to raising awareness and funds for sarcoma care. This year's event will take place at Mariposa Park, located directly across from UCSF Benioff Children's Hospital. Can't join us in person? No problem! Participate in our virtual 5K team from August 9 to 18, 2024, and join others from across the U.S. in raising funds to combat sarcoma.

Hosted by the Department of Orthopaedic Surgery

August 20, 12:00-1:00pm; Virtual Event

Education Scholarship Conference (ESCape)

Education Scholarship Conference (ESCape) is a weekly group consultation for scholarly work in health professions education with CFE faculty and other members of the UCSF education community.

RSVP for Zoom details.

Hosted by the UCSF Center for Faculty Educators

---

August 20, 12:00-1:30pm; Virtual Event

3D Printing Part 2: Introduction to 3D Modeling

Are you curious about the applications for 3D printing at UCSF? Join Makers Lab staff for the second pop-up in a three-part series covering the basics of 3D printing and how the technology can be used in the health sciences. Can’t make it to this pop-up? Self-enroll in the Makers Lab On-Demand CLE course to watch the recording.

Hosted by the UCSF Library

---

August 20, 12:10-1:00pm; Virtual Event

QB3 Webinar Series

Katharine Miller, Vice President, Global Head of Biologics Development Analytical and Quality, Bayer

"CMC Challenges and Opportunities for Cell and Gene Therapies"

Hosted by QB3

---

August 21, 1:00-2:00pm PT; Virtual Event

2024 CSR Summer Trainee Lecture Series

Beth Bragdon, PhD, Assistant Professor of Medicine, Department of Orthopaedic Surgery, Boston University School of Medicine

"Overview of Fracture Biology and Repair Strategies"

Join via Zoom.

Hosted by the Center for Musculoskeletal Research

---

August 22, 2:00-3:00pm; Mission Bay, Gladstone Institutes, Location TBD

IACUC Office Hours

Are you responsible for ensuring that your lab's IACUC protocol meets the highest animal welfare standards and will be approved as soon as possible? Are you wondering what the best blood collection technique for your study might be? Do you wish there was some way you could have someone show you how to use the RIO database for writing and submitting protocols? Get help with your questions at our bi-weekly office hours sessions.

Hosted by the UCSF Institutional Animal Care and Use Program

---

August 22, 4:30-6:00pm; Parnassus, CS-0101

Benioff Center for Microbiome Medicine Trainee Mixer

This event is open to all UCSF trainees conducting microbiome research.

Hosted by the UCSF Benioff Center for Microbiome Medicine

---

August 26-29; Mission Bay, Byers Auditorium & Virtual Events

UCSF Teaching and Learning Symposium

Join us for the third annual Teaching and Learning Symposium, a four-day event hosted by the UCSF Library and UCSF Teaching Innovations Work Group. This symposium is a unique opportunity for faculty educators, technologists, and education staff to delve into the future of health education, explore innovative learning modalities, and exchange best practices.

Hosted by the UCSF Library and UCSF Teaching Innovations Working Group

---

August 27, 9:00-10:00am PT; Virtual Event

INTERACT Pre-Application Webinar

The NIH HEAL Initiative^® has released a new funding opportunity for INTERACT (INTEgRAtive Back Pain Longitudinal Cohort Teams.) This funding opportunity solicits cooperative agreement applications from interdisciplinary teams to enhance longitudinal data collection and analysis among existing large-scale chronic lower back pain cohort studies. Join this webinar to learn more about application requirements.

Hosted by the NIH HEAL Initiative

---

August 28, 3:30-5:00pm; Virtual Event

Entrepreneurship: How to Assess Opportunities

Stephanie Marrus, Managing Director of Entrepreneurship at the UCSF Entrepreneurship Center will present, followed by a discussion with Michelle Arkin, PhD, UCSF, Professor, Dept. of Pharmaceutical Chemistry; Co-Director of the HDFCCC Small Molecular Discovery Center. Open to postdocs, grad students, faculty, and clinical fellows.

Hosted by the Helen Diller Family Comprehensive Cancer Center

---

August 28, 4:00pm; Mission Bay, MH-1407

Seminar Series for Junior Scientists

The Junior Scientist Seminar is a monthly seminar series and networking event exclusively for early-career researchers (pre-doctoral school). Our mission is to provide a career development and training opportunity for Junior Scientists to gain experience presenting scientific research in a supportive environment.

Hosted by the Research Development Office

---

August 29, 2:00-4:00pm; Virtual Event

C2C Seminar Series: Clinical Trial Protocol Structure & Review

This series of seminars will provide high-yield, practical information about designing, funding, and conducting patient-facing oncology trials.

Hosted by the Helen Diller Family Comprehensive Cancer Center

FUNDING OPPORTUNITIES

Career Awards at the Scientific Interface (CASI)

Letter of Intent Deadline: September 4, 2024 at 12:00PM PT

The Burroughs Wellcome Fund's CASI program supports the early career development of researchers who are dedicated to pursuing a career in academic research. The specific target group are researchers who have transitioned from graduate work in thephysical/mathematical/computational sciences or engineering into postdoctoral work in the biological sciences.

Proposals that include deep or machine learning applications of artificial intelligence are particularly encouraged. Special consideration will also be given to proposals that investigate theconnection between climate change and human health.

This program will provide $560,000 over five years to bridge advanced postdoctoral training and the first three years of faculty service.

If you're interested in applying, please email Liz Catalano to announce your intention. Afterwards, follow the application instructions in the RFP, conferring with your Grants Officer as needed.

PAR-23-236: Early-stage Biomedical Data Repositories and Knowledgebases (R24 Clinical Trial Not Allowed)

Application Deadline: September 25, 2024 at 5:00pm PT

This Notice of Funding Opportunity (NOFO) supports the development of early-stage or new data repositories or knowledgebases that could be valuable for the biomedical research community. The overall goal is to support pilot activities that demonstrate the need and potential impact of the data resource. The NOFO will also support transitioning resources that are currently supported as investigator-initiated research efforts into quality controlled, standards-based resources that address governance, and efficiency of operations. Efforts to consolidate existing data repositories or independent knowledgebases are also in scope for this NOFO.

To learn more, view the NOFO here.

HTORR Pilot Award Program

Application Deadline: October 1, 2024, at 5:00pm ET

The Pilot Award Program is a new component of our NIH-supported U42 program the Human Tissues and Organs for Research Resource (HTORR), and will support individuals that meet at least one of the following three high priority areas:

Individuals from underrepresented populations in the U.S. biomedical workforce, including women, minorities, persons with disabilities and persons from disadvantaged backgrounds.
Early-stage investigators that are within 10 years of a terminal degree or completion of clinical residency.
Established investigators that are transitioning to use human biospecimens.

The 2-year awards provided through our Pilot Award Program will include up to ~10 biological samples per awarded investigator, covering all costs associated with obtaining the biospecimens, including tissue preservation reagents and shipping costs. Beyond the service period and experimental analysis phase, the awardee will also receive supplementary support to develop grant applications to the NIH Institute that supported their award, and only applications that fall into the fields covered by these institutes will be reviewed.

The institutions currently supporting the Pilot Award Program are:

Office of Research Infrastructure Programs (ORIP)
National Institute of Allergy and Infectious Diseases (NIAID)
National Heart, Lung, and Blood Institute (NHLBI)
National Eye Institute (NEI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

To learn more, visit the HTORR website here.

Host an Open MIKE (MSK Integrated Knowledge Exchange)

Recognizing the need for collaboration of MSK scientists with experts outside of the MSK field, we are providing support to MSK Center members to host a meal for a creative and enjoyable in-person networking meeting to stimulate these interactions and to further develop new research ideas and plans to fund them. Faculty, staff, and trainees who are MSKC/CCMBM members are encouraged to apply to host an event.

If you are not a member, you may concurrently apply for membership while your Open MIKE application is being reviewed.

Apply via the online application form today! Contact Cristal Yee for questions on this funding opportunity.

UCSF Talks: An Informal Website for Discovery Science Seminars

UCSF Talks is a new resource for anyone interested in learning about the latest seminars happening at UCSF. It lists all seminars open to the entire UCSF community including regular seminar series, special seminars, supergroups, and thesis talks. If you would like to receive weekly event listing emails, you can sign up for the USCF Talks Google Group. To add an event to the website, please contact Jon Zhang.

ACKNOWLEDGING THE CCMBM

If you have received a CCMBM grant, used one of our cores, or formed a collaboration at one of our events that led to a publication, please acknowledge our Center in related publications and presentations. We suggest stating:

Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number P30AR075055. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.