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February 24, 2025

U-M Center for RNA Biomedicine's 9th Annual Symposium | March 6 – 8, 2025

Join us for the Center for RNA Biomedicine's 9th Annual RNA Symposium: From Sequence to Solutions, which also marks the inaugural event co-hosted by our new partner, The Society for RNA Therapeutics. This gathering brings together thought leaders and pioneering researchers in the fields of RNA science and biomedicine.


The premier three-day symposium will feature dynamic presentations, engaging panel discussions, and interactive sessions, all designed to push the boundaries of RNA research and foster interdisciplinary collaboration. Don't miss this opportunity


Click here to view and download the full program..

Don't miss out! The deadline for registration is

THIS Thursday, February 27th.

Registration Info

Featured 2025 RNA Symposium Speaker:

Muthiah "Mano" Manoharan, Ph.D.

Senior Vice President, Innovation Chemistry,

Scientific Advisory Board Member,

Distinguished Research Scientist

Alnylam Pharmaceuticals

Dr. Muthiah (Mano) Manoharan is a world-leading chemist in the areas of oligonucleotide chemical modifications, conjugation chemistry, and delivery platforms. Dr. Manoharan is currently Senior Vice President of Innovation Chemistry, a Scientific Advisory Board Member, and a Distinguished Research Scientist at Alnylam Pharmaceuticals. He and his team pioneered the discovery and development of the chemical modifications that make RNA interference-(RNAi) based human therapeutics possible. He has authored more than 215 publications and over 400 abstracts and is the inventor of more than 250 issued U.S. patents. Prior to Alnylam, Dr. Manoharan worked at Ionis (formerly Isis) Pharmaceuticals in the field of antisense oligonucleotide therapeutics. Dr. Manoharan has been honored with the 2019 Lifetime Achievement Award of the Oligonucleotide Therapeutics Society.

Center News

Michelle Hastings, Ph.D., director of RNA Therapeutics at U-M, to speak at Michigan Medicine's Rare Disease Day Symposium

This Friday, February 28th—National Rare Disease Day—Michigan Medicine will host a symposium featuring key discussions from researchers and advocates. Highlights include presentations by Dr. Michelle Hastings, Director of RNA Therapeutics, and Dr. Elizabeth Ames, pediatric geneticist at Mott Children's Hospital. Topics will cover the diagnostic odyssey and advancements in rare disease research.


The dialogue continues at next week's Center for RNA Biomedicine's 9th Annual RNA Symposium, where Dr. Ames and Dr. Peter Todd, clinical director of RNA Therapeutics, will co-moderate a patient advocacy panel. This event will explore the intersection of RNA research and patient care.


Both events showcase Michigan Medicine and the Center's commitment to advancing research and advocacy, inviting engagement from researchers, clinicians, and advocates.


Click here for more information on Friday's Rare Disease Symposium at Michigan Medicine.

Publications

Our members' publications are available through Altmetric.


Queries currently available:

CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation. Below are recent highlights.

Ali RH, Orellana EA, Lee SH, Chae YC, Chen Y, Clauwaert J, Kennedy AL, Gutierrez AE, Papke DJ, Valenzuela M, Silverman B, Falzetta A, Ficarro SB, Marto JA, Fletcher CDM, Perez-Atayde A, Alcindor T, Shimamura A, Prensner JR, Gregory RI, Gutierrez A. A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation. Mol Cell. 2025 Jan 28:S1097-2765(25)00003-6. doi: 10.1016/j.molcel.2025.01.003. Epub ahead of print. PMID: 39892392.

Zhang L, Li J, Walter NG. Pretrained Deep Neural Network Kin-SiM for Single-Molecule FRET Trace Idealization. J Phys Chem B. 2025 Jan 30;129(4):1167-1175. doi: 10.1021/acs.jpcb.4c05276. Epub 2025 Jan 14. PMID: 39809573.

Affiliated Seminars

“Local RNA translation in Kidney Disease”

Valerie Schumacher, Ph.D.

Assistant Professor of Medicine

Beth Israel Deaconess Medical Center

Harvard Medical School


Tuesday, February 25 | 3 p.m.


Click here to join via Zoom.


For questions reach out to Grace Lee at glee8@bidmc.harvard.edu

Meetings

For all details regarding each upcoming meeting, please click the banners below.

To share your news and comments, please contact

rna-communications@umich.edu

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