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April 22, 2024


RNA Innovation Seminar | Monday, May 6, 4 p.m.

“Using complex genetics in mice to unlock the secrets of cognitive resilience”


Catherine Kaczorowski, Ph.D.,

Elinor Levine Professor of Dementia Research,


Professor of Neurology,

University of Michigan Medical School


Monday, May 6, 4 p.m.,

ABC Seminar Rooms, BSRB


Click here for more information.

Special Center for RNA Biomedicine Seminar

Insider Insights: Exploring Good Manufacturing Practices (GMP) & Regulatory Standards in Pharma with Pfizer's Greg Digennaro — Virtual

"Pharmaceutical industry overview of good manufacturing practices and regulatory Chemical Manufacturing and Control requirements"

Greg Digennaro, Senior Manager — Regulatory

Chemical Manufacturing and Controls

Pfizer


Wednesday, April 24, 1 p.m.


Join the lecture via Zoom by clicking here.

U-M Seminars

Moses Gomberg Lecture Series

"Structural biology of bacterial antiphage defense"

Dinshaw Patel, Ph.D.,

Memorial Sloan Kettering Cancer Center


Monday, April 22, 4 p.m. | CHEM 1640


Hosted by U-M Center for RNA Biomedicine faculty member Sarah Keane, Ph.D.

Bioinnovations in Brain Chemistry Seminar

"Gene therapy for brain tumors: immune, cytotoxic, and novel long-term physical approaches"

Pedro Lowenstein, M.D., Ph.D.,

Neurosurgery,

Cell and Developmental Biology,

Center for RNA Biomedicine


April 26, 4 p.m. | Bldg. 10 Atrium, NCRC


If you do not have access to NCRC, please enter through Building 18.


BIBC-sponsored appetizers and drinks to follow at Carson's.

Lecture on Ethical Use of AI in Biomedical Research —

"Responsible and ethical use of artificial intelligence (AI) in biomedical research"

Brian Athey, Ph.D.,

Computational Medicine and Bioinformatics,

Psychiatry,

Center for RNA Biomedicine   


Tuesday, April 30, 3:30 p.m.

West Lecture Hall, MedSci II


For more information, visit Sessions @ Michigan or contact Theresa Nester at tnester@med.umich.edu

2024 Chemistry–Biology Interface Training Program Symposium

2024 Chemistry–Biology Interface Training Program Spring Symposium


Featuring:

Yamuna Krishnan, Ph.D., University of Chicago

Chase Weidmann, Ph.D, University of Michigan

Daniel Kober, Ph.D., University of Texas, SW


Monday, May 13, 8:30 a.m. – 4:30 p.m.

4th Fl. Amphitheatre, Rackham Graduate School


Register and submit your abstract using the CBI Training Program Symposium Google Form here.



Abstract submission deadline is April 29.

Registration deadline for non-presenters: May 13.

Affiliated Seminars

RNA Collaborative Seminar Series

The RNA Collaborative Seminar Series presents two fully virtual talks, hosted by the Yale Center for RNA Science and Medicine and moderated by Dr. Karla Neugebauer.


“Insights into regulated gene expression from RNA and protein chemistry”

Presented by Matt Simon, Ph.D.,

Department of Molecular Biophysics and Biochemistry,

Yale School of Medicine


"Cell surface RNAs in neutrophils"

Presented by Jun Lu, Ph.D.,

Department of Genetics

Yale School of Medicine


Wednesday, April 24, 4 p.m.


For further details—including how to register for the Zoom—please visit the RNA Collaborative Seminar Series website.

HMS Initiative for RNA Medicine Seminar Series

"The nucleolus, microRNAs and the human brain" 

Susan J. Baserga, M.D., Ph.D., Molecular Biophysics & Biochemistry

Yale University and Yale School of Medicine


Tuesday, May 7, 3 p.m.

Center for Life Sciences Bldg.

201 Brookline Ave., Boston, M.A. 02215


Seminar is also available via Zoom by clicking here.


For questions reach out to Grace Lee at glee8@bidmc.harvard.edu.

RNA Society

From our sponsor: Lexogen RNA Expertise Blog Series

Blog Posts: April 4, 9, and 10, 2024.

Read about formalin-fixed paraffin-embedded (FFFPE) samples in a new series of blog posts from Lexogen. Learn about what FFFPE samples are and how they are prepared, some applications of FFFPE samples in modern research, and the launch of Lexogen's new end-to-end solutions for FFFPE Transcriptomes.

In the News

New Study by Center Faculty Drs. Eva Feldman, Stephen Goutman, and Stuart Batterman Investigate ALS Risks Associated with Chemical Storage in Home Garages

Center members Feldman, M.D., Ph.D., Goutman, M.D., and Batterman, Ph.D.—alongside other U-M investigators—explored the dangers of storing chemicals, such as gasoline, pesticides, paint, and woodworking supplies, in your home garage.


They found that these chemicals stored in garages may lead to an increased ALS risk, especially those stored in attached garages in cold climates where air can be drawn through the garage and directly into the home.


Discover more about this exciting new work by center members in Noah Fromson's latest piece for Michigan Medicine's Healthlab.

Center Member's Awards and Honors

Three Center Members Recognized for Excellence in their Fields

Congrats, Dr. Feldman!

Eva Feldman, M.D., Ph.D. was awarded the prestigious Sheila Essey Award for ALS Research at the annual AAN meeting.

More information on the American Brain Foundation website.

Congrats, Dr. Li!

Jun Li, Ph.D. was recently inducted into the American Institute for Medical and Biological Engineering (AIMBE) College of Fellow.

Learn more on the U-M Computational Medicine and Bioinformatics (CMB) Website.

Congrats, Dr. Rajapakse!

Indika Rajapakse, Ph.D.'s lab was awarded a grant from the Defense Advanced Research Projects Agency (DARPA)

Find out more on the

U-M CMB website.


And read more about Dr. Rajapakse's groundbreaking work on page 58 in our latest issue of RNA Translated.

In Case You Missed It...

Center for RNA Biomedicine Faculty Share Groundbreaking Insights and Combat Skepticism Surrounding RNA Therapeutics at the 2024 American Association of Cancer Researchers Annual Meeting

Two weeks ago, during the 2024 AACR Annual Meeting, Dr. Mats Ljungman, co-director of the Center for RNA Biomedicine, delivered a talk titled "KLIPP: Precision targeting of cancer with CRISPR," aiming to generate interest in KLIPP, combat stigma and skepticism surrounding RNA therapeutics, and highlight the valuable work conducted by center faculty.


The center was well represented at AACR which also featured talks by center faculty members Dr. Arul Chinnaiyan, Dr. Sunitha Nagrath, Dr. Maria Castro, and Dr. Amanda Garner.


Read more about Dr. Ljungman's talk in this article by Paul Avedesian and check out Anna Megdell's Rogel Recap of the 2024 AACR Annual Meeting.

RNA Translated 2024 is Here!


We are pleased to announce that our latest edition of RNA Translated, the University of Michigan Center for RNA Biomedicine annual magazine and brief report, is available online now.


View and download an interactive, digital version of the magazine on our website, and enjoy the read!

Oral Defenses

"Computational methods in functional prioritization of polygenic risk score models"


Oral defense presented by

Bradley Crone, Bioinformatics

Advisor: Alan P. Boyle, Ph.D.


Friday, April 26, 9:15 a.m.

Forum Hall, Palmer Commons

"Analysis techniques for the characterization of circulating tumor cells and their immune interactions"


Oral defense presented by

Harrison Ball, Chemical Engineering

Advisor: Sunitha Nagrath


Friday, April 26, 1 p.m.

Research Auditorium, Bldg. 10, NCRC

"HIV VpR targets PU.1 in macrophages to evade the innate immune response and promote viral spread"


Oral defense presented by

Maria Virgilio, Cellular and Molecular Biology

Advisor: Kathleen Collins, M.D., Ph.D.


Friday, April 26, 1:30 p.m.

Kahn Auditorium, BSRB

"Investigating riboswitch-containing complexes via molecular dynamic simulations"


Oral defense presented by

Yichen Liu, Chemistry

Advisor: Nils Walter, Ph.D.


Wednesday, May 1, 9:30 a.m.

CHEM 1706 | Also available via Zoom by clicking here.

Upcoming Meetings

HIRM 2024 Symposium | This Thursday, April 25, 2024

HIRM 10 Year Anniversary Symposium


Thursday, April 25, 2024

Joseph B. Martin Conference Center,

77 Avenue Louis Pasteur,

Boston, MA 02115


Click here to register.

Poster submissions are closed.


For more information, contact Grace Lee at glee8@bidmc.harvard.edu.

RNA Society Annual Meeting | May 28 – June 2, 2024

RNA Society Annual Meeting 2024

 

May 28 – June 2, 2024

Edinburgh International Conference Centre

Edinburgh, Scotland


Organizers:

David Tollervey (Edinburgh)

Atlanta Cook (Edinburgh)

Ben Blencowe (Canada)

Markus Bohnsack (Germany)

Yue Wan (Singapore)


Click here to register.


For questions, please email rna2024@rnasociety.org.

6th Annual RNATx: From Concept to Clinic | June 26 – 28, 2024

2024 RNATx: From Concept to Clinic


June 26 – June 28, 2024

University of Massachusetts

Chan Medical School

55 Lake Avenue North

Worcester, Massachusetts.


Abstract submissions are closed.



Click here to register.


Click here for information on financial assistance, family support awards, and inclusivity grants for students and early career researchers!


Any questions, or for more information about the HBCU and Economically Disadvantaged Registration Waiver,

email rnatherapeutics@umassmed.edu.

GRC on Post-transcriptional Gene Regulation | July 14 – 19, 2024

Gordon Conference on

Post-transcriptional Gene Regulation —

Versatility of RNA in the Living World


July 14 – 19, 2024

University of Southern Maine

196 Falmouth Street,

Portland, Maine


The deadline for applications for the conference is June 16, 2024.

Apply early, space is limited.


For more information and to register, click here!

RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration in Ottawa: RNA Canada 2024: The Future of RNA Technology

RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration, taking place in Ottawa from September 30 to October 4, 2024

 

This milestone event promises to be extraordinary, with over 100 speakers, at least half of whom will be selected from submitted abstracts, ensuring a diverse and inclusive representation of leaders in the field.

 

As we celebrate 25 years of friendship, collaboration, and networking, This gathering marks the inauguration of RNA Canada, a new initiative aimed at strengthening the bonds between the international RNA community and our Canadian colleagues.


Download the complete program.

Non-coding RNA World 2024:

Exploring Mechanisms, Designing Medicines | October 7 – 9, 2024

Join us in Basel in October to learn about the latest developments in Non-Coding RNA research. Mingle with the world-leading invited speakers during ample networking opportunities. Present your research at poster sessions and numerous selected oral presentations. Discover the beautiful mediaeval city of Basel.

 

Click here for more information and details on abstract submissions. 

Publications

Our members' publications are available through Altmetric.


Queries currently available:

CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights.

Wells AE, Wilson JJ, Heuer SE, Sears JD, Wei J, Pandey R, Costa MW, Kaczorowski CC, Roopenian DC, Chang CH, Carter GW. Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice. PLoS One. 2024 Mar 7;19(3):e0299595. doi: 10.1371/journal.pone.0299595. PMID: 38451972; PMCID: PMC10919611.

Eid SA, Elzinga SE, Guo K, Hinder LM, Hayes JM, Pacut CM, Koubek EJ, Hur J, Feldman EL. Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy. Transl Res. 2024 Mar 29;270:24-41. doi: 10.1016/j.trsl.2024.03.009. Epub ahead of print. PMID: 38556110.

Wilhelm CA, Kaitany K, Kelly A, Yacoub M, Koutmos M. The protein-only RNase Ps, endonucleases that cleave pre-tRNA: Biological relevance, molecular architectures, substrate recognition and specificity, and protein interactomes. Wiley Interdiscip Rev RNA. 2024 Mar-Apr;15(2):e1836. doi: 10.1002/wrna.1836. PMID: 38453211.

Jones ASK, Hannum DF, Machlin JH, Tan A, Ma Q, Ulrich ND, Shen YC, Ciarelli M, Padmanabhan V, Marsh EE, Hammoud S, Li JZ, Shikanov A. Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencing. Sci Adv. 2024 Apr 5;10(14):eadm7506. doi: 10.1126/sciadv.adm7506. Epub 2024 Apr 5. PMID: 38578993; PMCID: PMC10997207.

Job Postings

The University of California Irvine (UCI), Department of Ophthalmology


Tenured or Tenure-Track Faculty

Inviting applicants focused on the development of genetic engineering and genome editing technologies.


Click here to learn more.

The Ohio State University (OSU),

Department of Molecular Genetics


Ohio Eminent Scholar in Molecular Genetics


The Ohio Eminent Scholars (OES) Program, created by the Ohio General Assembly and administered by the Ohio Board of Regents, aims to enhance the national eminence of selected outstanding academic programs at Ohio universities by attracting internationally recognized scholars. Applications are sought from those with a distinguished track record of investigating fundamental biological questions in any system.  

Postdoctoral Research Fellow and Graduate Research Assistants

Dr. Guizhi (Julian) Zhu Lab | University of Michigan


Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.

Recruitment Opportunities

For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website

To share your news and comments, please contact

rna-communications@umich.edu

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