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April 29, 2024


RNA Innovation Seminar | Next week, Monday, May 6, 4 p.m.

“Using complex genetics in mice to unlock the secrets of cognitive resilience”


Catherine Kaczorowski, Ph.D.,

Elinor Levine Professor of Dementia Research,


Professor of Neurology,

University of Michigan Medical School


Monday, May 6, 4 p.m.,

ABC Seminar Rooms, BSRB


Click here for more information.

U-M Seminars

Moses Gomberg Lecture Series

"DNA where you expect RNA: from fluorescent aptamers to stress granules"


Adrian Ferré-D'Amaré,

National Heart, Lung and Blood Institute, National Institute of Health, 


Today, Monday, April 29, 11 a.m.

CHEM 1640


Hosted by Markos Koutmos, Ph.D.


For more information, please visit the Gomberg Lecture Series website.

Lecture on Ethical Use of AI in Biomedical Research

"Responsible and ethical use of artificial intelligence (AI) in biomedical research"

Brian Athey, Ph.D.,

Computational Medicine and Bioinformatics,

Psychiatry,

Center for RNA Biomedicine   


Tomorrow, Tuesday, April 30, 3:30 p.m.

West Lecture Hall, MedSci II


For more information, visit Sessions @ Michigan or contact Theresa Nester at tnester@med.umich.edu

2024 Human Genetics Seminar Series

"Cell types of the last common animal ancestor as viewed through a ctenophoric lens"


Joseph F. Ryan, Ph.D.

Allen Distinguished Investigator,

Whitney Laboratory for Marine Bioscience,

University of Florida


Monday, May 6, 11 a.m.

5915 Buhl Classroom


Hosted by Anthony Antonellis, Ph.D.


More information can be found on the seminar series website or by emailing Jenny Russell at jkopeck@med.umich.edu.

2024 Chemistry–Biology Interface Training Program Symposium

2024 Chemistry–Biology Interface Training Program Spring Symposium


Featuring:

Yamuna Krishnan, Ph.D., University of Chicago

Chase Weidmann, Ph.D, University of Michigan

Daniel Kober, Ph.D., University of Texas, SW


Monday, May 13, 8:30 a.m. – 4:30 p.m.

4th Fl. Amphitheatre, Rackham Graduate School


Register and submit your abstract using the CBI Training Program Symposium Google Form here.

ABSTRACTS DUE TODAY – Monday, April 29.

Registration deadline for non-presenters: May 13.

Affiliated Seminars

RNA Collaborative Seminar Series

The RNA Collaborative Seminar Series presents a talk from Dr. Ana Tufegdžić Vidaković, hosted by the Cambridge RNA Club.


"Ubiquitin-mediated control of RNA polymerase II at the onset of the transcription cycle”

Ana Tufegdžić Vidaković, Ph.D.

MRC Laboratory of Molecular Biology

University of Cambridge


Wednesday, May 22, 2024, 10 a.m.


This is a fully virtual lecture. Register for the Zoom here.

HMS Initiative for RNA Medicine Seminar Series

"The nucleolus, microRNAs and the human brain" 

Susan J. Baserga, M.D., Ph.D., Molecular Biophysics & Biochemistry

Yale University and Yale School of Medicine


Tuesday, May 7, 3 p.m.

Center for Life Sciences Bldg.

201 Brookline Ave., Boston, M.A. 02215


Seminar is also available via Zoom by clicking here.


For questions reach out to Grace Lee at glee8@bidmc.harvard.edu.

From our Sponsor

NEW Lexogen Blog Post — April 24, 2024

In a new blog post, Lexogen announces their new solution for removing unwanted rRNA from plant samples, RiboCop rRNA Depletion for Plants.


Read more about the exciting development in this new blog post from the Lexogen website.

In the News

Center for RNA Biomedicine's Dr. Yan Zhang Wins Prestigious National Science Foundation (NSF) Award Honoring Excellence in Junior Faculty's Academic Leadership and Research


Yan Zhang, Ph.D., a faculty member at the Center for RNA Biomedicine was honored with the National Science Foundation's CAREER Award, securing a grant of $1.1 million over five years. The CAREER Award is the NSF's highest honor for junior faculty and is given to those who embody their position as academic role model while excelling at innovative research.


Dr. Zhang's research focuses on Type I CRISPR-Cas systems, aiming to better understand their mechanics and explore future utilities.


Learn more about Dr. Zhang's distinguished award and pioneering CRISPR research in a new article by Paul Avedisian.

In Case You Missed It...

Center for RNA Biomedicine hosted Pfizer’s Greg Digennaro last week in special lecture

The Center for RNA Biomedicine hosted Pfizer’s Greg DiGennaro last week, an expert in Chemical Manufacturing and Controls (CMC) and international pharmaceutical regulations, for an informative webinar.


In his talk, "Pharmaceutical Industry Overview of Good Manufacturing Practices and Regulatory CMC Requirements," Greg discussed navigating regulatory hurdles and Good Manufacturing Practices (GMP) in biomedical research and development.


Read the full story and watch a video recording of his presentation with accompanying slides on the Center for RNA Biomedicine website.

New Study by Center Faculty Drs. Eva Feldman, Stephen Goutman, and Stuart Batterman Investigate ALS Risks Associated with Chemical Storage in Home Garages

Center members Feldman, M.D., Ph.D., Goutman, M.D., and Batterman, Ph.D.—alongside other U-M investigators—explored the dangers of storing chemicals, such as gasoline, pesticides, paint, and woodworking supplies, in your home garage.


They found that these chemicals stored in garages may lead to an increased ALS risk, especially those stored in attached garages in cold climates where air can be drawn through the garage and directly into the home.


Discover more about this exciting new work by center members in Noah Fromson's latest piece for Michigan Medicine's Healthlab.

Three Center Members Recognized for Excellence in their Fields

Congrats, Dr. Feldman!


Eva Feldman, M.D., Ph.D. was awarded the prestigious Sheila Essey Award for ALS Research at the annual AAN meeting.


More information on the American Brain Foundation website.

Congrats, Dr. Li!


Jun Li, Ph.D. was recently inducted into the American Institute for Medical and Biological Engineering (AIMBE) College of Fellow.


More information is available in this article on the Michigan Medical School website.

Congrats, Dr. Rajapakse!


Indika Rajapakse, Ph.D.'s lab was awarded a grant from the Defense Advanced Research Projects Agency (DARPA)


Find out more in the article on the Michigan Medical School website.


And read more about Dr. Rajapakse's groundbreaking research in RNA Translated.

Oral Defenses

"Investigating riboswitch-containing complexes via molecular dynamic simulations"


Oral defense presented by

Yichen Liu, Chemistry

Advisor: Nils Walter, Ph.D.


Wednesday, May 1, 9:30 a.m.

CHEM 1706 | Also available via Zoom by clicking here.

Upcoming Meetings

Saltiel Life Sciences Symposium 2024: Celebrating 20 Years of Impact | May 20 and 21, 2024

Saltiel Life Sciences Symposium 2024: Celebrating 20 Years of Impact


On May 20 and 21, 2024, the University of Michigan Life Sciences Institute will host a special two-day Saltiel Life Sciences Symposium highlighting the impactful science and scientists that have emerged from the LSI’s first 20 years. 


Hosted by the LSI and

featuring Center for RNA Biomedicine faculty Janet Smith, Ph.D., Jay Brito Querido, Ph.D., Huda Akil, Ph.D., and more!


May 20 and 21, 2024

Kahn Auditorium, BSRB

RNA Society Annual Meeting | May 28 – June 2, 2024

RNA Society Annual Meeting 2024

 

May 28 – June 2, 2024

Edinburgh International Conference Centre

Edinburgh, Scotland


Organizers:

David Tollervey (Edinburgh)

Atlanta Cook (Edinburgh)

Ben Blencowe (Canada)

Markus Bohnsack (Germany)

Yue Wan (Singapore)


Click here to register.


For questions, please email rna2024@rnasociety.org.

6th Annual RNATx: From Concept to Clinic | June 26 – 28, 2024

2024 RNATx: From Concept to Clinic


June 26 – June 28, 2024

University of Massachusetts

Chan Medical School

55 Lake Avenue North

Worcester, Massachusetts.


Abstract submissions are closed.



Click here to register.


Click here for information on financial assistance, family support awards, and inclusivity grants for students and early career researchers!


Any questions, or for more information about the HBCU and Economically Disadvantaged Registration Waiver,

email rnatherapeutics@umassmed.edu.

GRC on Post-transcriptional Gene Regulation | July 14 – 19, 2024

Gordon Conference on

Post-transcriptional Gene Regulation —

Versatility of RNA in the Living World


July 14 – 19, 2024

University of Southern Maine

196 Falmouth Street,

Portland, Maine


The deadline for applications for the conference is June 16, 2024.

Apply early, space is limited.


For more information and to register, click here!

RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration in Ottawa: RNA Canada 2024: The Future of RNA Technology | September 30 – October 4, 2024

RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration, taking place in Ottawa from September 30 to October 4, 2024

 

This milestone event promises to be extraordinary, with over 100 speakers, at least half of whom will be selected from submitted abstracts, ensuring a diverse and inclusive representation of leaders in the field.

 

As we celebrate 25 years of friendship, collaboration, and networking, This gathering marks the inauguration of RNA Canada, a new initiative aimed at strengthening the bonds between the international RNA community and our Canadian colleagues.


Download the complete program.

Non-coding RNA World 2024:

Exploring Mechanisms, Designing Medicines | October 7 – 9, 2024

Join us in Basel in October to learn about the latest developments in Non-Coding RNA research. Mingle with the world-leading invited speakers during ample networking opportunities. Present your research at poster sessions and numerous selected oral presentations. Discover the beautiful medieval city of Basel.

 

Click here for more information and details on abstract submissions. 

EMBO Workshop: Spatial Omics and Complexities of Human Diseases: Resolve and Solve | October 23 – 25, 2024

EMBO Workshop: Spatial Omics and Complexities of Human Diseases: Resolve and Solve


Topics covered in this EMBO Workshop will include spatial tissue profiling and cell atlas, innovative multiplexed bio-imaging, cellular interactions, in situ multi-omics and AI-based data analysis.


October 23 – 25, 2024

Consiglio Nazionale delle Ricerche

Rome, Italy


For more information about this workshop and about abstract submissions, please visit the EMBO Workshop event page.

Publications

Our members' publications are available through Altmetric.


Queries currently available:

CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights.

Shen Q, Ruan H, Zhang H, Wu T, Zhu K, Han W, Dong R, Ming T, Qi H, Zhang Y. Utilization of CRISPR-Cas genome editing technology in filamentous fungi: function and advancement potentiality. Front Microbiol. 2024 Mar 28;15:1375120. doi: 10.3389/fmicb.2024.1375120. PMID: 38605715; PMCID: PMC11007153.

Eid SA, Elzinga SE, Guo K, Hinder LM, Hayes JM, Pacut CM, Koubek EJ, Hur J, Feldman EL. Transcriptomic profiling of sciatic nerves and dorsal root ganglia reveals site-specific effects of prediabetic neuropathy. Transl Res. 2024 Mar 29;270:24-41. doi: 10.1016/j.trsl.2024.03.009. Epub ahead of print. PMID: 38556110.

Wilhelm CA, Kaitany K, Kelly A, Yacoub M, Koutmos M. The protein-only RNase Ps, endonucleases that cleave pre-tRNA: Biological relevance, molecular architectures, substrate recognition and specificity, and protein interactomes. Wiley Interdiscip Rev RNA. 2024 Mar-Apr;15(2):e1836. doi: 10.1002/wrna.1836. PMID: 38453211.

Jones ASK, Hannum DF, Machlin JH, Tan A, Ma Q, Ulrich ND, Shen YC, Ciarelli M, Padmanabhan V, Marsh EE, Hammoud S, Li JZ, Shikanov A. Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencing. Sci Adv. 2024 Apr 5;10(14):eadm7506. doi: 10.1126/sciadv.adm7506. Epub 2024 Apr 5. PMID: 38578993; PMCID: PMC10997207.

Torrez RM, Nagaraja S, Menon A, Chang L, Ohi MD, Garner AL. Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA. Biochemistry. 2023 Jun 6;62(11):1725-1734. doi: 10.1021/acs.biochem.2c00687. Epub 2023 May 2. PMID: 37130292.

Job Postings

The University of California Irvine (UCI), Department of Ophthalmology


Tenured or Tenure-Track Faculty

Inviting applicants focused on the development of genetic engineering and genome editing technologies.


Click here to learn more.

The Ohio State University (OSU),

Department of Molecular Genetics


Ohio Eminent Scholar in Molecular Genetics


The Ohio Eminent Scholars (OES) Program, created by the Ohio General Assembly and administered by the Ohio Board of Regents, aims to enhance the national eminence of selected outstanding academic programs at Ohio universities by attracting internationally recognized scholars. Applications are sought from those with a distinguished track record of investigating fundamental biological questions in any system.  

Postdoctoral Research Fellow and Graduate Research Assistants

Dr. Guizhi (Julian) Zhu Lab | University of Michigan


Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.

For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website

Recruitment Opportunities

To share your news and comments, please contact

rna-communications@umich.edu

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