December 2023


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The IRB Review

A compilation of information, announcements, & updates for UK Institutional Review Board (IRB) members, research investigators, & others involved with human subject research.

Our Message To You...


ORI Review Services Highlights for the fiscal year 2022-2023 indicate researchers and IRB committee members have been very busy. Enjoy the winter break!

Holiday Closure - Dates & Deadlines

The Office of Research Integrity (ORI) will be closed Monday, December 25, 2023, through Monday, January 1, 2024, and will reopen on Tuesday, January 2, 2024. If you have received an Institutional Review Board (IRB) continuation review reminder, please check your approval end date and submit materials to ORI as soon as possible to prevent expiration of approval. 


In 1953, James Watson and Frances Crick determined the physical structure of DNA consisted of two linked strands, the double helix. The discovery led to the first complete DNA sequencing by Frederick Sanger who will receive a Nobel Prize in chemistry for his work in genomic research.  


The National Institute of Health (NIH) jumped on the DNA bandwagon in 1988 when an advisory committee was formed for the purpose of genomic research analysis. In 1989, the committee established the National Center for Human Genome Research renamed the National Human Genome Research Institute (NHGRI). The committee enlisted James Watson to head the Human Genome Project established in 1990.


December 1999 in Human Research History, BMJ Publishing released the news that scientists working on the Human Genome Project decoded the first complete human chromosome. BMJ 1999;319:1453

Is IRB review required for NIH funded research submitting whole genomic data to a national database like Genome-Wide Association Studies (GWAS)?

***Keep Reading for the Answer***

Upcoming ORI Office Hours

Tuesday, November 19, 12:00pm - 1:00 pm

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Click Here for All Office Hours Dates/Times



The Office of Research Integrity offers consultations by phone, Zoom, or in-person. Consultations are offered for studies in development (with or without an E-IRB submission) as well as approved research projects.

Click Here to Request a Consult

Answer to the Trivia Question:


Yes. Since 2015, the NIH Genome Data Sharing Policy (GDSP) requires the data sharing plan to be consistent with terms of the informed consent. For more info on human research and the  NIH Genomic Data Sharing Policy, see the ORI Guidance on the NIH Genome Data Sharing (GDS) Policy.