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December 18, 2023

Announcement for Winter Break


The RNA Transcript will pause publication in observance of the 2023-2024 Winter Break. Weekly publication will resume January 8, 2024. Keep an eye on your inbox!


Add the latest editions of The RNA Transcript. to this season's wish list, and catch up on your holiday reading!

Seminars

RNA Innovation Seminar Series Returns January 22, 2024 - Save the Date!

RNA Innovation Seminar Series


Anthony Rosenzweig, Ph.D.

Professor of Internal Medicine

Director of the MM Institute of Heart & Brain Health

University of Michigan


Monday, January 22, 4:00 PM - 5:00 PM ET

BSRB ABC Seminar Rooms, Hybrid Link

Upcoming Affiliated Seminars

HMS Initiative for RNA Medicine Seminar Series


"tRNA-derived small RNAs: novel functions in cellular stress response and disease pathways"


Saumya Das, MD, PhD , Associate Professor of Medicine, Harvard Medical School, Director of Resynchronization and Advanced Cardiac Therapies, Cardiac Arrhythmia Service, Mass General Hospital

 

Tuesday, December 19th, 2023 | 3:00 – 4:00 PM EST

Join us In-Person at Center Life Science Building (421) OR To Join Virtually Click This Link


RNA Research Centre in Poznań


Speaker Jakub Dolata, Group Leader, “microRNA biogenesis: co-transcriptional regulation and RNA modifications”


Speaker Zbigniew Warkock, PhD Postdoc, "LINE-1 mRNA 3' end dynamics shape its biology and retrotransposition potential"


Moderator: Magda Maslon, PhD


Wednesday, December 20, 2023, 10 AM CET  Zoom Registration

Oral Defenses

U-M Oral Dissertations

For more information and to view the full schedule of upcoming U-M Oral Defenses, please visit the Rackham Graduate School Oral Defenses website.

RNA Society

Lexogen RNA Expertise Blog Series

November 14, 2023


Lexogen Unveils LUTHOR High-Definition Single Cell 3’ mRNA-Seq Kit, Revolutionizing Single-Cell RNA Sequencing

In the News

Call for Poster Submissions!

8th Annual RNA Symposium - U-M Graduates and Postdocs*


As in years past, we will have an opportunity for trainees to present their work in the form of a poster session midway through the day, with the option of participating in one of several lighting talk sessions for a chance to introduce their work prior to the poster session.


Submissions are now open!


*Open to current University of Michigan graduate students and postdoctoral scholars. Applicants outside of the University of Michigan may be considered on a rolling basis if time slots remain vacant.

In Case You Missed It...

FDA Approves Two Sickle Cell Gene Therapies Including First CRISPR Drug

The US Food and Drug Administration on

Friday approved the first two gene therapies to treat

patients with sickle cell disease (SCD), including the first-

ever drug approved using CRISPR gene-editing technology.


Read the full story in Precision Medicine Online

Stephen Parker co-lead author of new paper linking gene network and pancreatic beta cell defects to type 2 diabetes

Center for RNA Biomedicine Faculty and Executive Committee Member Stephen C.J. Parker, Ph.D., Associate Professor, Departments of Computational Medicine & BioinformaticsHuman Genetics, and Biostatistics, just released new findings from a recent study on type 2 diabetes regulatory networks co-led by teams from the University of Michigan and Vanderbilt University. Read the full story.

Watch 2023 Nobel Prize lectures in physiology or medicine | Katalin Karikó and 2024 RNA Symposium speaker Dr. Drew Weissman | December 7, 2023

Dr. Weissman receives Nobel Prize. Watch the official ceremony recorded LIVE from Stockholm on Sunday, December 10

Save The Date

2024 RNA Symposium | March 8, 2024 - Registration is now open!

Unmasking the Power of RNA: From Structure to Medicine

"Unmasking the Power of RNA: From Structure to Medicine"


The 8th annual symposium will take place on Friday, March 8, 8:30 a.m. - 5:00 p.m. in the A. Alfred Taubman Biomedical Science Research Bldg., Kahn Auditorium at 109 Zina Pitcher Place in Ann Arbor, Michigan. Speakers include:




Download the 2024 RNA Symposium Flyer

HIRM 2024 Symposium, April 25, 2024

2024 Symposium

 

HIRM 10 Year Anniversary Symposium

Thursday, April 25, 2024

 

Joseph B. Martin Conference Center

77 Avenue Louis Pasteur

Boston, MA 02115


Exciting News! RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration in Ottawa: RNA Canada 2024: The future of RNA technology

RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration, taking place in Ottawa from September 30 to October 4, 2024

 

This milestone event promises to be extraordinary, with over 100 speakers, at least half of whom will be selected from submitted abstracts, ensuring a diverse and inclusive representation of leaders in the field.

 

As we celebrate 25 years of friendship, collaboration, and networking, This gathering marks the inauguration of RNA Canada, a new initiative aimed at strengthening the bonds between the international RNA community and our Canadian colleagues.


Download the complete program.

Our members' publications are available through Altmetric. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights. Bold denotes CRB member.

Hatfield BM, Weidmann CA, Weeks KM. Measuring Proximity-Mediated Function of mRNA Regulatory Proteins by Engineered Tethering. Methods Mol Biol. 2024;2723:143-159. doi: 10.1007/978-1-0716-3481-3_9. PMID: 37824069; PMCID: PMC10621603. https://doi.org/10.1007/978-1-0716-3481-3_9

Goutman SA, Boss J, Jang DG, Mukherjee B, Richardson RJ, Batterman S, Feldman EL. Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort. J Neurol Neurosurg Psychiatry. 2023 Sep 27:jnnp-2023-332121. doi: 10.1136/jnnp-2023-332121. Epub ahead of print. PMID: 37758454. https://doi.org/10.1136/jnnp-2023-332121

Smith TJ, Giles RN, Koutmou KS. Anticodon stem-loop tRNA modifications influence codon decoding and frame maintenance during translation. Semin Cell Dev Biol. 2024 Feb 15;154(Pt B):105-113. doi: 10.1016/j.semcdb.2023.06.003. Epub 2023 Jun 28. PMID: 37385829. https://doi.org/10.1016/j.semcdb.2023.06.003

Wilhelm CA, Mallik L, Kelly AL, Brotzman S, Mendoza J, Anders AG, Leskaj S, Castillo C, Ruotolo BT, Cianfrocco MA, Koutmos M. Bacterial RNA-free RNase P: structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P. J Biol Chem. 2023 Oct 6:105327. doi: 10.1016/j.jbc.2023.105327. Epub ahead of print. PMID: 37806495. https://doi.org/10.1016/j.jbc.2023.105327

Hou Q, Chatterjee S, Lund PE, Suddala KC, Walter NG. Single-molecule FRET observes opposing effects of urea and TMAO on structurally similar meso- and thermophilic riboswitch RNAs. Nucleic Acids Res. 2023 Oct 19:gkad866. doi: 10.1093/nar/gkad866. Epub ahead of print. PMID: 37855661. https://doi.org/10.1093/nar/gkad866

Job Postings

Postdoctoral Fellow UMich Department of Pathology


The laboratory of Dr. Sethu Pitchiaya, Assistant Professor, Department of Urology, Department of Pathology at the University of Michigan seeks to hire an enthusiastic Postdoctoral fellow to work on exciting projects related to mammalian stress response mechanisms. Learn more.

University of Michigan BIBC Tenure Track Faculty Search


The University of Michigan has launched a Tenure Track Faculty Search for the BioInnovations in Brain Cancer Initiative (BIBC), led by Center for RNA Biomedicine Faculty Member Dr. Maria G. Castro and Dr. Steven Schwendeman. Learn more.

The University of California Irvine (UCI), Department of Ophthalmology

Full-Time Position


Inviting applicants focused on the development of genetic engineering and genome editing technologies. Learn more.

Postdoctoral Research Fellow and Graduate Research Assistants

Dr. Guizhi (Julian) Zhu Lab | University of Michigan


Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.

Research Technician and Post-Doctoral Research Fellow | Fred Hutchinson Cancer Center | The Lapointe Lab


Seeking to fill two positions: Research Technician and Post-Doctoral Research Fellow. Learn more.

Research Technician - Yadavalli Lab



Seeking full-time technician or research scientist to perform cutting-edge research in RNA biology using high-throughput sequencing methods. Learn more.

Postdoctoral Position - Maquat Lab


A postdoctoral position is open. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology. Learn more.

Postdoctoral Position - Cooperman Laboratory


Seeking postdoctoral student with a strong interest in understanding the mechanism and regulation of cytoplasmic eukaryotic protein synthesis. Learn more.

Recruitment Opportunities

For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website

To share your news and comments, please contact

rna-communications@umich.edu

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