Article - Ice Formation and Its Elimination In Cryopreservation of Oocytes | |
In an article in Nature, Robert E. Thorne* et al. explore ice formation in bovine oocytes during rapid cooling and warming, examining the impact of cryoprotective agent (CPA) concentration, cooling rates, and warming rates on ice formation. Synchrotron-based time-resolved x-ray diffraction was utilized to analyze the nature of ice formed during these processes. The study revealed that ice-related damage primarily occurs during warming, with the behavior of ice depending on its formation during cooling. Larger cooling rates were found to prevent ice formation in oocytes soaked in standard concentrations during both cooling and warming. *Robert E. Thorne is the founder of MiTeGen. | |
Protective Apparel For Handling Liquid Nitrogen | | |
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Working with liquid nitrogen demands the utmost protection. Our new line of specialized apparel safeguards you from head to toe, including gloves, aprons, gaiters, and face shields, all designed to withstand the extreme cold of cryogenic applications. Choose from various sizes and colors to ensure a comfortable and secure fit.
Don't compromise your safety. Click the button below to explore our full range of cryogenic protective gear.
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Ludo Frevel Crystallography Scholarship | | |
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The ICDD is accepting applications for the 2024 Ludo Frevel Crystallography Scholarship. The scholarship is designed to encourage promising graduate students to pursue crystallographically oriented research. Application deadline is October 12th.
Learn more about this scholarship and Ludo Frevel by clicking the button below.
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Quantifoil R 1.2/1.3 200 Mesh Copper Grids | | |
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We recently received an extra supply of Quantifoil R 1.2/1.3 200 mesh copper grids in the 100-pack size. These grids are usually challenging to come by, and when they are available, they sell out quickly.
This is your chance to stock up and avoid the multi-month delay usually associated with this grid. Use the button below to contact us. Include the SKU M-CEM-Q2100CR1.3 in your inquiry. | |
Sea Coast 2024 Meeting Report | | |
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We sponsor many events throughout the year. One of the first events in 2024 we sponsored was the South East Asian Crystallographic Overview And Systematic Training (SEA COAST). The course covered all aspects of macromolecular crystallography and was designed to benefit researchers at various levels of their expertise.
A meeting summary report has been published in the IUCr Newsletter. You can read it by clicking the button below.
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The Fragment-Based Lead Discovery
Conference will be held from September 22nd - 25th in Boston, Massachusetts. The conference features
experts in chemistry, biochemistry, and related disciplines discussing the latest developments in fragment-based lead discovery. The conference includes talks, workshops, poster sessions, and more. We are exhibiting at this event.
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The Structural Biology Platform FINStruct and Instruct-ERIC Centre Finland annual meeting will be held on November 7th in Oulu, Finland. The event consists of talks by invited speakers, young scientists, and companies and a poster session to present your work and meet the staff of various core facilities. We are a sponsor of this event | |
Events, Workshops and Conferences | | |
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If you are looking for more events, please visit our events page. It lists conferences, workshops, symposiums, user meetings, and more.
Topics include structural biology, material science, crystallography, cryo-EM, beamline research, and more.
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Industry Resources and News | |
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Here is a small selection of industry resources and news for your browsing.
- Preprint at bioRxiv, Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies - Learn More
- Research Article at eLife, Observing one-divalent-metal-ion-dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo - Learn More
- Article at Diamond Light Source, Warming up to room-temperature crystallography - Learn More
- Paper at Acta Cryst C, The challenges of growing great crystals – or at least good enough ones - Learn More
- Article at Crystal Growth & Design, Using Data from the Cambridge Structural Database to Practice Crystallographic Skills and Revise Erroneous Structures - Learn More
- CCDC Cambridge Resource, crystallography education resource hub, Learn More
- From Protein Data Bank In Europe, Educational resources including introductory and advanced tutorials on biomacromolecular structure, tutorials on different PDBe services and more - Learn More
- From Diamod Light Source, Crystallography Group Update 2023-24 covering the scientific, technical, computing and business updates from the facility - Learn More
- Article at MDPI Crystals, Screening, Growing, and Validation by Catalog: Using Synthetic Intermediates from Natural Product Libraries to Discover Fragments for an Aspartic Protease Through Crystallography - Learn More
- Paper at Acta Cryst D, Surface-mutagenesis strategies to enable structural biology crystallization platforms - Learn More
- Paper at Acta Cryst D, Post-translational modifications in the Protein Data Bank, Learn More
- Paper at IUCrJ, CheckMyMetal (CMM): validating metal-binding sites in X-ray and cryo-EM data - Learn More
- Article at Nature Communications Biology, CryoTRANS: predicting high-resolution maps of rare conformations from self-supervised trajectories in cryo-EM - Learn More
- Paper at J. Appl. Cryst., From solution to structure: empowering inclusive cryo-EM with a pre-characterization pipeline for biological samples - Learn More
- Paper at IUCrJ, Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination - Learn More
- Published at Princeton, CryoBench: Diverse and challenging datasets for the heterogeneity problem in cryo-EM - Learn More
- Preprint at bioRxiv, Protein identification using cryo-EM and artificial intelligence guides improved sample purification - Learn More
- Article at Argonne National Laboratory, Advanced Photon Source achieves world-record electron beam emittance measurement - Learn More
- Press release from CERN, Students from Estonia, Japan and the USA win the 11th edition of Beamline for Schools - Learn More
- Paper at Synchrotron JSR, Accelerating imaging research at large-scale scientific facilities through scientific computing - Learn More
- Learn how you can visit ALBA Synchrotron in Spain either virtually or in person - Learn More
- Find beamline proposal deadlines from around the world at Lightsources.org -Learn More
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20th Anniversary - Custom Engineering | |
Celebrating two decades of innovation, MiTeGen's custom engineering prowess has been instrumental in empowering scientific breakthroughs. From tailoring existing products to crafting entirely new solutions, we've consistently met the unique needs of researchers in crystallography, cryo-EM, and beyond. Our expertise in microfabrication and engineering enables us to transform concepts into reality, as exemplified by our custom foam dewars, loops, environmentally controlled chambers, manual plunge coolers and more. As we mark our 20th anniversary, we reaffirm our commitment to pushing boundaries and collaborating with scientists to shape the future of discovery through custom-engineered solutions. | |
Have your lab be the first to know. Follow us on social media! | | | | |
