John S. Dunn Behavioral Sciences Center

receives impact award

The state-of-the-art John S. Dunn Behavioral Sciences Center at UTHealth Houston has received accolades for being a piece of art itself.


The Houston chapter of the Urban Land Institute awarded the UTHealth Houston Department of Facilities, Planning, and Engineering the Development of Distinction Award in the Not-for-Profit category as part of its 2023 awards.


“I feel like the most blessed person on the face of the earth to have worked on this project because it means so much to so many. My heart was in it, the contractor’s heart was in it, and now it’s making an impact in the hearts of others,” said Ginger Smith, senior facilities construction project manager, who oversaw the building’s construction.


It took five years of planning and construction to erect the 253,000-square-foot facility, which includes 264 inpatient beds. Sitting adjacent to UTHealth Houston Harris County Psychiatric Center, the two facilities together are the largest academic psychiatric hospital in the nation. It was built in partnership with the Texas Health and Human Services Commission and the Texas Medical Center. The university worked with design firm Perkins + Will and contractor Vaughn Construction on the project.


“The success of this project was a team effort,” said Julie Lucas, associate vice president of Facilities Planning, Design, and Construction. “The Facilities project team — made up of Ginger Smith, Brady Smyth, Robin Murtishaw, Gerard Marchand, Steven Bennett, Bobby Watson, and Wes Stewart — is top in class and partnered to make this facility state-of-the-art while staying on schedule and budget.”


Part of the building’s allure is that it doesn’t feel like a traditional mental health facility, with its tall windows and natural light.


“The design of the building intentionally focused on bringing natural light into the space as a whole,” said Daniel Doyle, MS, DrPH, CPHQ, UTHealth Houston Behavioral Sciences Campus’ chief quality officer and chief operating officer. “There was a neuroscientist on the design team who felt strongly that light is an integral part in the healing of patients. It feels lighter and brighter than any hospital, let alone a behavioral hospital. I think that is uplifting to patients, staff, and visitors.”


The new facility is intended to be a new standard of care in Texas, and UTHealth Houston leadership took an active role to ensure patient care remained at the center of the mission, even during planning and construction of the building.


“Mental health care has been associated with stigma, but this building exemplifies the modern care of mental health,” said Lokesh Shahani, MD, PhD, MPH, UTHealth Houston Behavioral Sciences Campus Chief medical officer and associate professor in the Faillace Department of Psychiatry and Behavioral Sciences. “When you walk in, the modern environment exudes the modern clinical care we provide.”


Significant care was put into every detail of building construction — putting the safety of patients, providers, and visitors at the center of every decision — right down to the screws used in the building, which cannot be easily removed with common utensils.


Based on staff feedback, each unit has a long, central nurse station that is open to the large central room. From the station, staff can see almost every angle of the unit. Therapy rooms have glass walls to provide visibility, and frosted windows to give patients privacy.


The facility boasts two enclosed courtyards with a walking trail, and the spacious cafeteria has outdoor seating options. Attention to detail in the courtyards was a priority for the UTHealth Houston safety team. Safety Specialist Cedric Peace researched what trees to plant to avoid potentially poisonous seeds.


“The outdoor space adds to the recovery process,” Doyle said. “Some of our patients stay between 90 to 120 days, and having outdoor avenues to explore means a lot. The grounds were designed to facilitate patient engagement with pathways that allow patients to interact with nature as well as architectural elements. It’s been well received by patients and staff.”


The facility also boasts features to train the next generation of health professionals

with leading-edge technology that allows for improved instructional opportunities.



“The modernization of this hospital is a step in advancing the modern care we give to our patients and the training we provide to the next generation of health care professionals,” Shahani said.

Spravato offers new alternative in fight against treatment-resistant depression

Jair C. Soares, MD, PhD

Joao de Quevedo, MD, PhD

Clinicians at the Faillace Department of Psychiatry and Behavioral Sciences are using a new way to battle treatment-resistant depression with an esketamine nose spray called SPRAVATO®.


Treatment-resistant depression may affect as many as one-third of people who suffer from the disorder. Medications are not effective for those living with treatment-resistant depression. As a result, these patients have difficulty enjoying life and being productive.


In a clinical study, people who used Spravato, combined with an oral anti-depressant, experienced reduced depressive symptoms compared to those who took a placebo.



Watch Jair Soares, MD, PhD, Pat R. Rutherford, Jr. Chair in Psychiatry, talk a little more about Spravato and how the medication helped Megan Kidd, who was referred to the UTHealth Houston Innovations Clinic, get some relief from the treatment-resistant depression she’s lived with her whole life. 

Watch the story

MindGames team wins back-to-back championships

(Photo from: Caroline McCool/UTHealth Houston)

For the fifth time in 11 years, the UTHealth Houston Psychiatry MindGames team brought home the trophy from the national competition of the American Psychiatric Association (APA), thanks to team members Caroline McCool, MD; Hunter Hinman, MD; and Daniel Liaou, MD. They also gave UTHealth Houston bragging rights with back-to-back championships.


MindGames is a national residency team competition hosted by the APA as a fun way for residents to test their knowledge on patient care, medical knowledge, and psychiatric history. Teams from across the country compete against each other on a preliminary qualifying exam, and the top three teams advance to a live Jeopardy-style final round.

 

The residents were invited to compete together by Vineeth John, MD, MBA, professor and vice chair for education in the Faillace Department of Psychiatry and Behavioral Sciences. McCool and Hinman are returning members from last year’s championship team, while Liaou was joining for the first time. Team members emphasized this was a total department effort to win the competition.

 

The department has a strong history of success in the MindGames competition with previous wins coming in 2008, 2012, 2013, and 2022. Though it is a friendly competition, the team members wanted to perform well for the department.

 

“It was really wonderful getting to compete in person this year at APA,” McCool said. “We had a great time virtually last year, but being on stage and having so many of our classmates in the crowd cheering us on made the energy at this year's event so exciting and fun! We are honored to represent UTHealth Houston and proud to bring the trophy back home again!”


“The UTHealth Houston Mindgames Team was exceptionally prepared and willing to take chances with tough questions," John, who has worked with four UTHealth Houston victories, said. "To be at the 2023 live competition was a nerve-racking, heart-pounding, and exhilarating experience. We have been fortunate to have sustained success in back-to-back years. Along with our sense of immense pride in our team is an appreciation for the richness of the field of psychiatry, which sits at the luminous intersection of science, culture, art, movies, and literature."

 

Read more about the MindGames competition here.

Spotlight:

Two from department receive grants

Heather Webber, PhD, received an $889,300 K-Award from the National Institute on Drug Abuse (NIDA) for her project, "Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder." 

 

Summary of the project: Cocaine use disorder is a chronic, relapsing condition with severe public health impacts and limited effective treatment options. Transcranial magnetic stimulation (TMS) holds promise for treating those suffering from addiction. This proposal aims to assess the effects of TMS on brain reactivity markers that contribute to poor treatment outcomes and has the potential to advance NIDA’s objective of developing novel treatments that specifically target underlying neurobiological mechanisms.


Webber is an instructor in the Faillace Department of Psychiatry and Behavioral Sciences. Her area of focus is human electrophysiological methods to study the underlying neural mechanisms of motivation, reward and punishment sensitivity, and emotional functioning and how these processes contribute to addiction. 


Camila Nayane de Carvalho Lima, PhD, received a $70,000 2022 NARSAD Young Investigator Grant from the Brain and Behavior Research Foundation for her project, "Molecular Mechanisms Underlying Accelerated Epigenetic Aging in Bipolar Disorder: A Transcriptomic and Neuroanatomical Study." 

 

Summary of the project: Bipolar disorder is one of the main global causes of disability and is associated with premature mortality due to increased rates of suicide and medical comorbidities. This major public health problem has been consistently recognized as a cause of accelerated aging, which can lead to poor health outcomes and elevated patient mortality risk. However, much is still unknown about the underlying mechanisms of accelerated aging in bipolar disorder and ways to prevent it. With no known anti-aging treatments for the disorder, the search for novel therapeutics to address this health problem is critical.



This application aims to investigate premature aging in bipolar disorder and the effects of metformin and lithium on aging markers, namely telomere length, mitochondrial DNA copy number, and epigenetic aging in human induced pluripotent stem cells (hiPSC) derived from bipolar disorder patients and controls. This project addresses the Brain and Behavior Research Foundation’s mission of translationally investigating a critical health issue in psychiatric illness, using an innovative hiPSC model of epigenetic aging, and testing possibilities for reversing aging.


Lima is a postdoctoral fellow in the Faillace Department of Psychiatry and Behavioral Sciences. Her area of focus is studying aging in bipolar disorder, showing the relationship between bipolar disorder and accelerated aging. 

Early bird registration for the Addictions Conference

is still open!

Registration for the 2023 UTHealth Houston Addictions Conference, titled “The Kids Aren’t Alright: Youth Substance Use Prevention and Treatment,” is now open! The conference will be held at the InterContinental Houston-Medical Center, 6750 Main St. Houston, TX 77030 on Friday, August 25.

 

The conference will provide practitioners with the latest advances in the epidemiology and etiology of the disorder, as well as prevention and treatment of substance use in youth. Clinicians will be introduced to the opportunities for treatment and challenges associated with adolescent substance use, including consideration of unique neurobiological and social concerns in this age group.


A special research blitz will showcase ongoing studies on prescription stimulants in youth, the e-cigarette epidemic, and cannabis use in youth.


Early bird registration is being extended through Monday, July 31 at 11:59 p.m. Visit https://go.uth.edu/23AddConf and use code “EARLYBIRD20ADD” at checkout to receive the discount. After July 31, there will be no other discounts offered, so sign up early!



We hope to see you all at the 2023 UTHealth Houston Addictions Conference

Clinical trials

The following clinical trials are in operation, following all necessary safety guidelines. If you're interested, contact the appropriate study.


Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

We are conducting a study to develop adaptive treatment interventions that change based on how the participant is doing. Individuals seeking treatment for cocaine addiction may qualify to participate in this two-phase program. 

Contact: 713-500-DRUG (3784)


Stem Cells for Treatment-Resistant Bipolar Depression

This study aims to examine the safety and efficacy of allogenic mesenchymal stem cells as an adjunctive treatment for treatment-resistant bipolar depression. Patients will be assigned into a treatment or a placebo group. 

Contact: 713-486-2627


VNS RECOVER Study

Researchers in the UTHealth Houston Center of Excellence on Mood Disorders are studying the VNS therapy LivaNova device to treat depression as part of the RECOVER trial.

Contact: 713-486-2627


To see all open studies, visit our website.

Publications
In the news

Did we finally find a good animal model for bipolar disorder? - Molecular Psychiatry - June 2023

Samira S. Valvassori, João Quevedo, and Giselli Scaini


Efficacy and adverse effects of ketamine versus electroconvulsive therapy for major depressive disorder: A systematic review and meta-analysis - PubMed - June 2023

Debora de A Simoes MoreiraLuís Eduardo GauerGuilherme TeixeiraAmanda Carolina Fonseca da SilvaStefanie CavalcantiJoão Quevedo


Jair Soares, MD, PhD, spoke to KPRC-TV Channel 2 about storm anxiety during hurricane season. 


Soares also spoke to KPRC-TV Channel 2 about a clinical trial testing whether stem cell therapy can combat treatment-resistant bipolar disorder.


Cesar Soutullo, MD, PhD, spoke to National Geographic about how Adderall and Ritalin won’t work for people who do not have ADHD.


Andrea Taylor, PhD, appeared on Houston Public Media’s Town Square with Ernie Manouse to talk about what trauma looks like and how it can develop into post-traumatic stress disorder (14:00 mark).


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Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School at UTHealth Houston

713-486-2500

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