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The RNA Transcript, March 27th 2023

News

7th Annual Symposium Survey

Thank you for participating in the 7th Annual Center for RNA Biomedicine Symposium.


Please complete the symposium survey:


Survey


Thank you.


News

Innovation Partnerships - Great Lakes Discovery

Congratulations to Dr. David Markovitz, whose project has been the first Great Lakes Discovery project that has been selected for Deerfield Management funding.


The announcement link from Innovation Partnerships is here.

Seminars

RNA Collaborative Seminar

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Alberta RNA Research & Training Institue (ARRTI)


On the mathematical modeling of eIF5B-mediated non-canonical translation initiation as a chemotherapeutic target

Speaker: Elizabeth Trofimenkoff



Nucleolin Interacts with ZIKV RNA Terminal Regions and Modulates Virion Assembly

Speaker: Darren Gemmill



Moderator: Laura Keffer-Wilkes, Ph.D


Wednesday, March 29, 2023.

4:00 PM

Zoom.

CPOD Seminar

Pioneering the Developmental Frontier


Melissa Harrison, Ph.D

Associate Chair

Molecular Cellular & Developmental Biology

University of Wisconsin-Madison


Tuesday, March 28, 2023.

4:00 PM

BSRB ABC Seminar Room Zoom.


For additional information contact:

organogenesis@umich.edu 

U-M RNA Innovation Seminar

Talk Title TBA


Haiyuan Yu, Ph.D

Professor

Department of Biological Statistics & Computational Biology

Weill Institue for Cell & Molecular Biology

Cornell University


Monday, April 10, 2023

4:00 - 5:00 PM

ABC Seminar Room, Zoom

Registration Deadlines



March 31st - RNA Society Poster-Only Abstracts Due

RNA SOCIETY

28th Annual Meeting of the RNA Society - May 30th thru June 4th

RNA 2023 - the 28th Annual Meeting of the RNA Society - will be held at the Suntec Convention Center in downtown Singapore from May 30th - June 4th. 

 

Registration is now open

 

Look forward to seeing you there.

Job Opportunities

University of Michigan - Postdoctoral Position

Post-doctoral position in the lab of John Prensner, MD Ph.D

Chad Carr - Pediatric Brain Tumor Center, Michigan Medicine


Translating the cancer genome for children with brain tumors

One post-doctoral position is available in the Prensner lab in the Chad Carr - Pediatric Brain Tumor Center at the University of Michigan to study the therapeutic implications of non-canonical RNA translation in pediatric brain cancers. This is a fully funded position. We are supportive of post-doctoral research fellows obtaining independent funding and/or career development awards to advance their independent academic careers.


The successful candidate will be able to advance cancer-related work around our active projects in:

- RNA translational regulation

- Therapeutic targeting of RNA translation

- Non-canonical open reading frames

- Non-coding genome translation.


We use a variety of high-throughput techniques, functional genomics, biochemical and computational methods to investigate the cancer-relevant consequences of aberrant RNA translation. Recent publications: Prensner JR et al., Nature Biotechnology, 2021; Mudge JM*, Ruiz-Orera J*, Prensner JR*, et al., Nature Biotechnology, 2022.


Applicants should hold a PhD or equivalent degree (MD, MD/PhD) and have experience with molecular or developmental biology, cancer biology, or murine model systems of cancer.


Interested individuals should send a curriculum vitae and cover letter to prensner@umich.edu or

Submit an application via: https://careers.umich.edu/job_detail/230384/research-fellow

University of Rochester - Postdoctoral Position

Post-doctoral Position Lab of Lynne Maquat, Ph.D

Director, Center for RNA Biology

Professor, Departments of Biochemistry & Biophysics, Oncology, and Pediatrics

School of Medicine and Dentistry


A Post-Doctoral Position is open in the Maquat Lab at the University of Rochester Medical Center in Rochester, NY. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology to study one of a number of very exciting and ongoing projects, including but not limited to FMRP function in Fragile X Syndrome (FXS), newly defined effectors of nonsense-mediated mRNA decay, or the mechanistic coupling of transcription and RNA processing on chromatin and beyond. A background in neurobiology and/or stem-cell biology would facilitate the work on FXS (see, e.g., https://www.nature.com/articles/s41556-020-00618-1), and a background in computational biology would facilitate all projects, but neither is required.  


Interested individuals should submit: 

a complete curriculum vitae, 

the names and email addresses of three references (applicants should state their relationship to each), and 

a description of RNA research experience, including experimental approaches and technologies with which the applicant has experience. 


The successful applicant will join a very productive, interactive lab and a lively, supportive RNA community that consists of more than 25 labs spanning the University of Rochester Medical Center and the adjacent Colleges of Arts, Sciences & Engineering. The Maquat lab offers an outstanding research environment, excellent opportunities to collaborate with basic scientists and clinicians, and a strong record of training post-docs for academic positions.


Please submit applications to: Liz at elizabeth_leverenz@urmc.rochester.edu 

Meetings

2023 RiboClub Annual Meeting - September 24 - 28

The RiboClub Annual Meeting aims at encouraging the exchange of ideas and stimulates collaborations between RNA biologists around the world. The meeting covers different topics related to the chemistry, structure and biology of RNA with emphasis on upcoming and debatable biological questions. In addition, every year the RiboClub puts the focus on a local or regional RNA group to highlight their efforts and introduce them to the international community.

The meeting format provides principal investigators the opportunity to present their point of views on the current state of knowledge and ignite the curiosity of young scientists. The meeting size and its format give ample opportunity for discussions and interactions, so bring your thinking hat to uncover the next big idea.

Registration fees are subsidized to encourage the participation of students and upcoming researchers. All laboratory members are invited to attend, listen to the presentations of leading scientists and participate in poster competition.


Annual Meeting September 24-28, 2023

Chéribourg Hotel, Orford, Quebec, Canada


Register by: June 30th, 2023

More Inforamtion :www.riboclub.org

Questions: riboclub@riboclub.org

Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights.


Mandal, S., Khanna, K., Johnson-Buck, A., & Walter, N. G. (2022). A guide to accelerated direct digital counting of single nucleic acid molecules by FRET-based intramolecular kinetic fingerprinting. Methods (San Diego, Calif.)197, 63–73. Highlighted in NCI's Epidemiology & Genomics Research Program (EGRP) https://doi.org/10.1016/j.ymeth.2021.06.014

Wang, E. T., Freudenreich, C. H., Gromak, N., Jain, A., Todd, P. K., & Nagai, Y. (2023). What repeat expansion disorders can teach us about the Central Dogma. Molecular cell, 83(3), 324–329. https://doi.org/10.1016/j.molcel.2022.12.017

Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, Maria Luisa Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, Joseph F. Costello, Daniel P. Cahill, Pedro R. Lowenstein, Maria G. Castro; Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance. Clin Cancer Res 2023; https://doi.org/10.1158/1078-0432.CCR-22-1896

To share your news and comments, please contact rna-communications@umich.edu

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