|
Science Showcase
- Stanley Manne Children's Research Institute Names Fall 2024 Internal Funding Awardees
News from the Manne Research Institute Pillars
- NIH Provides Critical Funding for Pediatric Clinical Trials in Diseases Not Prioritized by Industry, Study Shows
- Drug May Prevent Some Migraine Attacks in Children and Teens
Manne Research Institute in the Media
Have research news to share? Submit it here.
| | |
|
Stanley Manne Children's Research Institute Names Fall 2024 Internal Funding Awardees
Stanley Manne Children’s Research Institute has announced the recipients of the fall 2024 internal funding opportunities. Manne Research Institute provides internal grant and award opportunities to a faculty member or other person who has principal investigator-eligible status to develop projects that will lead to a highly competitive extramural application for sustained research support within 18 months of receiving the award. Funding opportunities vary depending on the year and cycle. Pediatric research at Ann & Robert H. Lurie Children’s Hospital of Chicago is conducted through Stanley Manne Children’s Research Institute.
| |
|
Isabelle De Plaen, MD
Attending Physician, Neonatology, Ann & Robert H. Lurie Children’s Hospital of Chicago; Professor of Pediatrics (Neonatology), Northwestern University Feinberg School of Medicine
Award type: Proposal Revision Award
Amount funded: $100,000
Title: Downregulation of VEGFR2 Signaling by Inflammatory Macrophages and NEC
| |
|
|
Jeanne Frisby-Zedan, MD
Attending Physician, Nephrology (Kidney Diseases), Ann & Robert H. Lurie Children’s Hospital of Chicago; Assistant Professor of Pediatrics (Nephrology), Northwestern University Feinberg School of Medicine
Award type: Catalyst’s Spark Award
Amount funded: $100,000
Title: Optimization of Pediatric Hospital-Acquired Acute Kidney Injury Follow-up Utilizing a Risk Prediction Model for Development of Chronic Kidney Disease and a Community-Engaged Approach
| |
|
|
Gal Finer, MD, PhD
Attending Physician, Nephrology (Kidney Diseases), Ann & Robert H. Lurie Children’s Hospital of Chicago; Assistant Professor of Pediatrics (Nephrology), Northwestern University Feinberg School of Medicine
Award type: Kenneth C. Griffin Research Catalyst Award
Amount funded: $100,000
Title: Enhancing Kidney Organoid Technology with TCF21 Integration for Improved ADPKD Modeling and Therapeutic Discovery
| |
|
|
Seth Goldstein, MD, MPhil
Attending Physician, Pediatric Surgery, Ann & Robert H. Lurie Children’s Hospital of Chicago; Director, Surgical Simulation Program, Lurie Children’s; Associate Professor of Surgery, Northwestern University Feinberg School of Medicine
Award type: Accelerator Award: Innovate2Impact Commercialization Fund
Amount funded: $64,744
Title: Device to Reduce Intra-Cavitary Abscess Rates in Minimally Invasive Surgeries
| |
|
|
Susan Horner, PhD, APRN-CNS
Founder’s Board Nurse Scientist and Developmental Specialist, Neonatal Intensive Care Unit, Ann & Robert H. Lurie Children’s Hospital of Chicago
Award type: Schreiber GROW to 5: Thrive Award
Amount funded: $50,000
Title: Impact of H-HOPE Intervention on Infants with Congenital Defects and Their Parents
| |
|
|
Monica Laronda, PhD
Director of Basic and Translational Research, Fertility and Hormone Preservation and Restoration Program, Stanley Manne Children’s Research Institute; Gesualdo Family Research Scholar, Ann & Robert H. Lurie Children’s Hospital of Chicago; Assistant Professor of Pediatrics, Northwestern University Feinberg School of Medicine
Award type: Proposal Revision Award
Amount funded: $85,000
Title: The Role of Neovascularization on Ovarian Transplant Longevity
| |
|
|
Joanna K. Ledwon, PhD
Research Assistant Professor, Surgery (Pediatric General Surgery), Northwestern University Feinberg School of Medicine
Award type: Accelerator Award: Innovate2Impact Commercialization Fund
Amount funded: $40,000
Title: Validation of a Novel Sensor to Monitor Skin Growth
| |
|
|
Elizabeth Managlia, PhD
Research Assistant Professor, Northwestern University Feinberg School of Medicine
Award type: Visionary Award
Amount funded: $75,000
Title: Necrotizing Enterocolitis-Induced Junctional Adhesion Molecule-Like Protein (JamL) Impairs Postnatal Intestinal Lymphatic Development
| |
|
Andrea C. Pardo, MD, FAAP, FCNS
Attending Physician, Neurology, Ann & Robert H. Lurie Children’s Hospital of Chicago; Medical Director, Ruth D. & Ken M. Davee Pediatric Neurocritical Care Program, Lurie Children’s; Associate Professor of Pediatrics (Neurology and Epilepsy), Northwestern University Feinberg School of Medicine
Award type: Interdisciplinary Colloquia Award
Amount funded: $5,000
Title: Pediatric Neurocritical Care Symposium
| |
|
|
Audrey Raut, MD
Attending Physician, Child Abuse Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago; Assistant Professor of Pediatrics (Child Abuse), Northwestern University Feinberg School of Medicine
Award type: Schreiber Family Center GROW to 5 Nourish Award
Amount funded: $50,000
Title: Impact of the Early Exposome on Relational Health Outcomes and Risk of Child Maltreatment: Planning Grant Proposal for a Biobehavioral Study of Parent-Child Interaction Therapy (PCIT)
| |
|
|
Arun Sharma, PhD
Director, Pediatric Urological Medicine and Surgical Research, Ann & Robert H. Lurie Children’s Hospital of Chicago and Stanley Manne Children’s Research Institute
Award type: Accelerator Award: Innovate2Impact Commercialization Fund
Amount funded: $50,000
Title: Autologous Stem Cell Therapy for Urinary Bladder Tissue Regeneration
| |
|
|
Milagros Suarez, PhD
Post Doctoral Associate, Xiao-Nan Li Laboratory, Stanley Manne Children’s Research Institute, Ann & Robert H. Lurie Children’s Hospital of Chicago
Award type: Accelerator Award: Innovate2Impact Commercialization Fund
Amount funded: $76,850
Title: Growth Media Formulations for Pediatric Brain Tumor Organoids
| |
|
|
Xiaocai Yan, PhD
Research Assistant Professor, Northwestern University Feinberg School of Medicine
Award type: Kenneth C. Griffin Research Catalyst Award
Amount funded: $100,000
Title: Role of IL17 in Bridging Adaptive and Innate Immunity in NEC
| |
|
Courtney Zulauf-McCurdy, PhD
Clinical Community Psychologist, The Pritzker Department of Psychiatry and Behavioral Health
Award type: Schreiber Family Center GROW to 5 Thrive Award
Amount funded: $50,000
Title: Developing a Core Menu of Strategies to Improve the Implementation of Behavioral Interventions for ADHD in Preschools
| |
| |
|
NEWS FROM THE RESEARCH PILLARS | |
|
The National Institutes of Health (NIH) serves as an important source of funding for clinical trials in children, especially for diseases, such as cancer, that are not as highly prioritized in industry-sponsored clinical trials, according to a recent study published in The Journal of Pediatrics. The study evaluated how the number of pediatric clinical trials, as an indicator for industry and NIH research priorities, compared with the burden of childhood disease in the United States.
“We observed that NIH funded key research areas that are less often prioritized by industry, and this is critical for establishing new treatments that children need,” said lead author Ansh Goyal, MD, a surgical resident at the University of Colorado Anschutz Medical Campus. Dr. Goyal was a medical student at Northwestern University Feinberg School of Medicine while conducting the study.
| |
|
For children and teens living with migraine, there may be a new preventive treatment, according to a preliminary study released February 26, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online. Researchers found the drug zonisamide, which has been used to treat seizures, may reduce migraine days in this age group. This study does not prove that zonisamide reduces migraine days; it only shows an association.
“Migraine disease is debilitating and can lead to kids having to miss school and other activities,” said author Anisa Kelley, MD, director of the Headache Program at Ann & Robert H. Lurie Children’s Hospital of Chicago and assistant professor of Pediatrics at Northwestern University Feinberg School of Medicine. “Currently, there is only one FDA-approved migraine preventative medication for this age group. Our results are encouraging, showing zonisamide may be another option for reducing migraine attacks.”
| |
MANNE RESEARCH INSTITUTE IN THE MEDIA | | | | |
