How do you approach a patient with asymptomatic esophageal eosinophilia?

-         Asymptomatic esophageal eosinophilia (aEE) is defined as a condition with an esophageal eosinophilia with at least 15 eos/HpF without any typical or atypical esophagus-related symptoms.

-         Prevalence of 60-80 cases/100,000 persons.

-         Patients with aEE are less likely to have concomitant allergic diseases than EoE patients (44 vs. 76%, p <0.01). No difference in endoscopic features.

-         Although no long-term therapy is necessary, the possibility of a progressive disease with fibrosis formation much be kept in mind, so that regular monitoring, both clinically and endoscopically, seems justified.