Researchers develop one of the first sleep-screening methods to predict, detect Parkinson's onset

Researchers have now developed one of the first screening methods during sleep to detect early manifestations of Parkinson's disease—using a non-invasive, low-cost, remote, and scalable technology already embedded in most wearable sleep and fitness trackers known as accelerometers. Click here to learn more.

Movement disorders in mitochondrial disease, pt. 1

A broad spectrum of movement disorders can manifest in mitochondrial diseases including ataxia, Parkinsonism, myoclonus, dystonia, choreoathetosis, spasticity, tremor, tic disorders and restless legs syndrome. Click the video image to learn about mitochondria and their possible dysfunction in individuals with neurodegenerative diseases.

The speaker featured in this video is a research associate at the Knoebel Institute for Healthy Aging at the University of Denver working with Daniel Paredes, Ph. D, who in 2020 was the first recipient of a Movement Disorders Foundation Pilot Grant to fund innovative research.

Effects on different neurons may explain how symptoms evolve in Huntington's disease

“As many as 10 years ahead of the motor diagnosis, Huntington’s patients can experience mood disorders," according to Ann Graybiel, PhD, professor at Massachusetts Institute of Technology (MIT). One possibility is that the striosomes [the striatal compartment involved in regulating mood] might be involved in these [disorders].” Click here to learn more.

Chinese scientists’ stem cell experiment raises hopes for effective Parkinson’s disease treatment

Researchers in China have developed a new stem cell therapy for Parkinson’s disease which showed rapid and lasting effects on monkeys. If proven effective on humans, the genetically engineered cells could be mass-produced and potentially provide an affordable, off-the-shelf treatment to millions around the world. Click here to learn more.

Movement disorders in mitochondrial disease, pt. 2

Learn about research being conducted at the Knoebel Institute for Healthy Aging at the University of Denver on senescence and mitochondrial motility in the final part of our two-part series on mitochondria. Click the video image for more information.

The speaker featured in this video is a research associate at the Knoebel Institute for Healthy Aging working with Daniel Paredes, Ph. D, the first recipient of a Movement Disorders Foundation Pilot Grant to fund innovative research.