June 24, 2024

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NRG 2024 Summer Meeting Registration is Open!

Join us for the NRG Oncology Summer Meeting July 25th - July 27th at the Sheraton Denver Downtown Hotel in Denver, CO. The Meeting will be held in-person only (with limited virtual session offerings). REGISTER TODAY! Registration after July 2^nd will incur a late fee.

#NRG2024 Social Media Workshop – Virtual Session

The NRG Oncology Communications Committee is pleased to announce our Social Media Workshop as part of #NRG2024. The workshop, being held as a virtual session, is scheduled for Monday, July 22, 2024, 10-11am EDT. Drs. Kristin Higgins and Miriam Knoll, members of the NRG Oncology Communications Committee, are the workshop chairs. The session speakers include Dr. Amy Comander from Massachusetts General Hospital; she will be discussing advocacy and lifestyle medicine; Dr. Stephen Chun from MD Anderson and Dr. Lauren Henke from University Hospitals/Case Western University will be presenting about NRG’s new Podcast Project. Please see the session flyer for details. Register here for the session.



Social Media Ambassadors wanted for #NRG2024

Apply to be a Social Media Ambassador for the #NRG2024 Summer Meeting in Denver. If interested, please send an e-mail (& please include your social account handle/s) to: communications@nrgoncology.org.

ACTIVATION

GYNECOLOGIC

NRG-GY032: Reactivation June 24, 2024; version date: March 27, 2024 (posted on CTSU)

AMENDMENTS

GENITOURINARY

NRG-GU009: Amendment 4, version date: May 16, 2024 (posted on CTSU)

GYNECOLOGIC and LUNG

The following protocol amendments, which are in response to an NCI Action Letter, dated June 14, 2024, for CTEP-supported studies that involve durvalumab, are posted with study-specific instructions on individual study pages

• NRG-GY012: Amendment 8; protocol version date: May 23, 2024 (posted on CTSU)
• NRG-GY023: Amendment 4; protocol version date: May 23, 2024 (posted on CTSU)
• NRG-LU004: Amendment 7; protocol version date: May 28, 2024 ((protocol posted on CTSU; memo posted on NRG)
• NRG-LU008: Amendment 1; protocol version date: May 28, 2024 (posted on CTSU)
• RTOG 1308: Amendment 7; protocol version date: May 28, 2024 (posted on CTSU)

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

2. BIOSPECIMEN BANKS

Shipping samples in extreme weather conditions

The NRG Oncology Biospecimen Bank staff would like to remind you to keep in mind weather conditions when shipping samples. 

• Be sure to add sufficient dry ice to frozen shipments. In extreme temperatures, if possible, store the samples in -80° C until the temperature comes down.
• Frozen biospecimens should be shipped to the bank on Monday through Wednesday for Tuesday through Thursday delivery.
• Do not ship any biospecimens the day before a holiday. Watch the NRG Weekly Broadcasts for holiday closure notices and instructions.
• Be aware of the weather conditions in your area and where the biospecimens will be shipped.
• In temperatures over 80° F, use a cool pack when shipping FFPE blocks.
• Always refer to the protocol or manual (Biospecimen Collection and Submission Manual or Pathology and Correlatives Manual) for shipping instruction. 

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

3. BREAST

NRG-BR008/HERO: Site Call Invitation. Please see the memorandum, dated June 6, 2024, (posted on CTSU) for details and how to register for one of the sessions on June 25 or 26. Please note: Google Chrome is the preferred browser to register for the webinars.

4. CANCER PREVENTION & CONTROL

NRG-CC010: The study is open to NRG sites in Japan and South Korea. The optional biospecimen collection does not apply to sites participating in these countries.

5. GENITOURINARY

SUMMARY OF RESEARCH RESULTS FOR PATIENTS

NRG-GU003: A summary of research results is available on the NRG Patient Study Web Page.

6. GYNECOLOGIC

NRG-GY028: ETCTN has approved the submission of unstained slides when a block absolutely cannot be submitted. This will be included in the next protocol amendment. Until such time, details regarding this alternate submission can be found here.

NRG-GY031: Please note, there is an error in the section 4.2 table and the Biospecimen Collection and Submission Manual. The Part I PK collection is to be done on Cycle 1, Day 1, and Cycle 1, Day 8. This will be updated with the next amendment.

7. HEAD & NECK

NRG-HN008 - Reminder: Please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

Drug Safety updates have been issued for the following studies:

Independence Day Holiday Closures

The NRG Oncology Operations offices, Statistics and Data Management Centers (SDMCs), Biospecimen Banks, and McKesson's Clinical Research Services will be closed on Thursday, July 4, 2024 in observance of the Independence Day holiday. In addition, the Philadelphia West Operations office and the Philadelphia SDMC office will be closed on Friday, July 5. Please refer to the memo posted on CTSU for more information about these closures and shipping information for the banks.

NRG Oncology GYN Cancer Committee is Requesting Proposals for Clinical Trials in Advance of the July 25-27 Summer Semiannual Meeting

Deadline: June 28, 2024 Read more here

NRG Oncology is pleased to report the following scientific articles that have appeared during the previous week as well as abstracts accepted for presentation at the American Society for Radiation Oncology (ASTRO).

This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

ACCEPTED ABSTRACTS

Corredor G, Harris J, Koyuncu C, Pathak T, Pandav K, Toro P, Yang K, Faraji F, Castro P, Sandulache V, Koyfman SA, Rosenthal DI, Nguyen-Tân PF, Garden AS, Caudell JJ, Jones CU, Le Q, Lewis JS Jr., Madabhushi A. Metrics Derived From Architecture Of Tumor-Infiltrating Lymphocytes Are Associated With Overall Survival In HPV-Associated Oropharyngeal Squamous Cell Carcinoma Patients: Results From RTOG 0522 And 0129. ASTRO (American Society for Radiation Oncology). 9/29/2024. Oral Presentation.

Simone CB II, Hu C, Heinzerling JH, Mileham KF, Higgins KA, Lin L, Abazeed ME, Ohri N, Bradley JD. NRG LU008: Phase III Prospective Randomized Trial Of Primary Lung Tumor Stereotactic Body Radiation Therapy (SBRT) Followed By Concurrent Mediastinal Chemoradiation For Locally-Advanced Non-Small Cell Lung Cancer (LA-NSCLC). ASTRO (American Society for Radiation Oncology). 9/29/2024. Poster Presentation.

PUBLISHED ARTICLES

Karrison T, Hu C, Dignam J. Scaling and interpreting treatment effects in clinical trials using restricted mean survival time. Clin Trials. 2024 Jun 13:17407745241254995. doi: 10.1177/17407745241254995. Epub ahead of print. PMID: 38872319. Read more.

Sloan AE, Winter K, Gilbert MR, Aldape K, Choi S, Wen PY, Butowski N, Iwamoto FM, Raval RR, Voloschin AD, Kamiya-Matsuoka C, Won M, Mehta MP. NRG-BN002: Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GBM. Neuro Oncol. 2024 Jun 14:noae058. doi: 10.1093/neuonc/noae058. Epub ahead of print. PMID: 38874333. Read more.

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Brachytherapy Society (ABS) World Congress; Jul 10-13, 2024; National Harbor, MD

Canadian Association of Radiation Oncology (CARO); Sep 11-14, 2024; Vancouver, BC

European Society for Medical Oncology (ESMO); Sep 13-17, 2024; Barcelona, Spain

European Society for Medical Oncology (ESMO) Gastrointestinal; Jun 26-29, 2024; Munich, Germany

International Society for Quality-of-Life Research (ISOQOL); Oct 13-16, 2024; Cologne, Germany

PA Breast Cancer Coalition (PBCC); Oct 15, 2024; Harrisburg, PA

Radiological Society of North America (RSNA); Dec 1-5, 2024; Chicago, IL

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Society for Radiation Oncology (ASTRO); Sep 29-Oct 2, 2024; Washington, DC; LBA Jul 12, 2024

EORTC-NCI-AACR Symposium on Molecular Targets and therapies; Oct 23-25, 2024; Barcelona, Spain; submission deadline Jun 27, 2024; LBA Sep 26, 2024

European Society of Gynaecological Oncology (ESGO); Feb 20-23, 2025; Rome, Italy; due to publications committee Oct 14, 2024; submission deadline Oct 28, 2024; LBA Jan 15, 2025 (placeholder required)

International Gynecologic Cancer Society (IGCS); Oct 16-18, 2024; Dublin, Ireland; LBA Jul 2, 2024, 23:59 IST

San Antonio Breast Cancer Society (SABCS); Dec 10-14, 2024; San Antonio, TX; due to publications committee Jun 26, 2024; submission deadline Jul 10, 2024, 11:59 pm CT; LBA Sep 30, 2024, 11:59 pm CT

Society for Immunotherapy of Cancer (SITC); Nov 6-10, 2024; Houston, TX; submission deadline Jun 27, 2024; LBA Sep 12, 2024

Society for Neuro-Oncology (SNO); Nov 21-24, 2024; Houston, TX; LBA Sep 3, 2024, 5:00 pm ET (placeholder required)

Society of Surgical Oncology (SSO) Annual Meeting; Feb 14-17, 2025; Scottsdale, AZ; due to publications committee Sep 16, 2024; submission deadline Sep 30, 2024

SSO – Advanced Cancer Therapies; Mar 27-29, 2025; Tampa, FL; due to publications committee Sep 2, 2024; submission deadline Sep 16, 2024