The RNA Transcript, February 6th 2023 | | |
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DNA Nanostructures: From Design to Biological Function
Hanadi Sleiman, PhD
Professor of Chemistry
McGill University
Tuesday, February 7, 2023
4:00 - 5:00 p.m.
Chem 1640
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RNA Collaborative Seminar | | |
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Tropomyosin 1-I/C co-ordinates kinesin-1 and dynein motors during oskar mRNA transport
Speaker: Simone Heber, Ph.D
Postdoctoral Fellow
The structural basis of intron branch site recognition by the human spliceosome
Speaker: Jonas Tholen, Ph.D
Postdoctoral Fellow
Moderator: Wojtek Galej, Ph.D
Wednesday, February 15, 2023.
10:00 am.
Zoom.
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U-M RNA Innovation Seminar | | |
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Why did the RNA Cross the Nanotube? Many questions and (some) answers on tuelling-nantoube medicated RNA transfer between mammalian cells
Gal Haimovich, Ph.D.
Assistant Staff Scientist
Department of Molecular Genetics
Weizmann Institute of Science
Monday, February 13, 2023
12:00 - 1:00 p.m.
Virtual Only, Zoom
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The Landscape of Mitochrondrial Translation in Health and Human Disease
James Marks, Ph.D.
Postdoctoral Fellow
RNA Molecular Biology Laboratory
National Institute of Health
Monday, February 13 2023
12:00 PM
BSB 1010
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U-M RNA Innovation Seminar | | |
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A Complicated Family: Conserved and Distinct Functions of tRNA Methyltransferases from Yeast to Humans
Jane Jackman, Ph.D.
Professor of Chemistry & Biochemistry
The Ohio State University
Monday, February 27 2023
4:00 - 5:00 PM
BSRB ABC Seminars
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U-M Medical School - Fellowship Application | | |
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The Research Operations, Management & Strategy (ROMS) Fellowship Application
The ROMS Fellowship is a two-year, paid, full-time position at the U-M Medical School designed to transition biomedical trainees from the bench to careers in research operations and administration through a series of unit rotations, hands-on learning experiences, and direct mentorship from leaders in the field.
The application will be open January 1 – February 19, 2023.
Any additional questions can be addressed to ROMS.Fellowship@umich.edu
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OSU Nakanishi Lab - Postdoctoral Position Application | | |
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Postdoctoral Position to Explore “Tiny RNAs” in Humans
An NIH-funded postdoctoral position is available in the laboratory of Dr. Kotaro Nakanishi at The Ohio State University. The Nakanishi group studies the roles of tiny RNAs, 10 - 18 nt non coding RNAs. We recently discovered that specific 3′→5′ exonucleases trim microRNAs to
tiny RNAs. While more than 200,000 papers about microRNAs have been reported, only about 10 articles have described tiny RNAs. The physiological functions of tiny RNAs remain to be studied. My group uses molecular biology, biochemistry, RNA-seq, cell biology (confocal microscope), and structural biology (cryo-EM and crystallography) to investigate tiny RNAs. We are looking for a postdoc who explores this new world together.
Qualifications
Strong candidates are highly motivated individuals with an excellent academic track record, including first-author publication(s). Candidates should have or be in the process of completing a Ph.D. in biochemistry, molecular biology, cell biology, or structural biology. Experience in large-scale protein purification and structure determination in cryo-EM and/or X ray crystallography will be advantageous.
To apply
For more information, please visit HERE.
Questions
If you have any questions, please email nakanishi.9@osu.edu.
Recent publications:
1. Sim GY, Kehling AC, Park MS, Secor J, Divoky C, Zhang H, Malhotra N, Bhagdikar D, Abd El Wahab EW, Nakanishi K. (2022). Proc. Natl. Acad. Sci. USA.
2. Park MS, Sim GY, Kehling AC, Nakanishi K (2020). Proc. Natl. Acad. Sci. USA. 3. Park MS, Araya-Secchi R, Brackbill JA, Phan HD, Kehling AC, Abd El-Wahab EW, Dayeh DM, Sotomayor M., Nakanishi K. (2019). Molecular Cell.
4. Dayeh DM., Cantara WA., Kitzrow J., Musier-Forsyth K., Nakanishi K. (2018). Nucleic Acids
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RNA Structure and Folding Prediction Guided by Innovative Technologies - Funding Opportunities | | |
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IN-PART Discover is running a Request for Proposals (RFP) on behalf of their client, AstraZeneca. As part of their biannual CoSolve Challenge.
Deadline to register: March 10th
Registration Link Here
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6th International Course on "Post-transcriptional Gene Regulation: From Mechanisms to RNA Chemistry & Therapeutics" - Conference | | |
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The 6th international course on “Post-transcriptional gene regulation: from mechanisms to RNA chemistry and therapeutics" will take place on 24-28 April 2023 at Institut Curie in Orsay (Paris area, France).
We would greatly appreciate if you could transfer this information to your team and colleagues.
For more information, please visit the course webpage: https://training.institut-curie.org/courses/post-transcriptional-gene-regulation-2.
Deadline to register: February 17th
Registration is free but mandatory HERE.
Audience: Master and PhD students coming from European laboratories.
Candidates are selected based on their CV & a letter of motivation (mentioning the research theme and the authorization from the PI).
We would greatly appreciate if you could transfer this information to your team and colleagues.
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SAVE THE DATE 28th Annual Meeting of the RNA Society | | |
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RNA 2023 - the 28th Annual Meeting of the RNA Society - will be held at the Suntec Convention Center in downtown Singapore from May 30th - June 4th.
Please SAVE THE DATE and plan to attend. Registration to open early February!
Look forward to seeing you there.
Best wishes,
Organizing Committee, RNA 2023
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SAVE THE DATE University of Michigan Center for RNA Biomedicine's 7th Annual RNA Symposium. March 24th, 2023 | | |
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2023 Symposium
7th Annual RNA Symposium, “From Molecules to Medicines”
Friday, March 24, 2022, 8:30am – 4:00pm
A. Alfred Taubman Biomedical Science Research Bldg, Kahn Auditorium
109 Zina Pitcher Pl, Ann Arbor, Michigan
Keynote Speakers:
Steve Henikoff, PhD, Genome-wide Mapping of Protein-DNA Interaction Dynamics
Fred Hutchinson Cancer Research Center
Professor & HHMI Investigator, Basic Science Division
Jody Puglisi, PhD, Talk Title TBA
Stanford University
Professor, Department of Structural Biology
Director, Stanford Magnetic Resonance Laboratory
Geraldine Seydoux, PhD, Talk Title TBA
Johns Hopkins University
Huntington Sheldon Professor in Medical Discovery
Professor of Molecular Biology & Genetics
Amy Gladfelter, PhD, The RNA Code in Condensates
University of North Carolina at Chapel Hill
Associate Professor of Biology
Joe Wedekind, PhD, Redefining Riboswitches: Ribosome-Binding Site Sequestration is Dispensable for Gene Regulation by the Largest Group of preQ, Riboswitches
University of Rochester, Medical School
Professor of Biochemistry & Biophysics
More details of the day's agenda will be available in February
Registration Ends: Friday March 10th, 2023.
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Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, Maria Luisa Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, Joseph F. Costello, Daniel P. Cahill, Pedro R. Lowenstein, Maria G. Castro; Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance. Clin Cancer Res 2023; https://doi.org/10.1158/1078-0432.CCR-22-1896 | |
McMillan, M., Gomez, N., Hsieh, C., Bekier, M., Li, X., Miguez, R., Tank, E. M. H., & Barmada, S. J. (2023). RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia. Molecular cell, 83(2), 219–236.e7. https://doi.org/10.1016/j.molcel.2022.12.019 | |
Nemudraia, A., Nemudryi, A., Buyukyoruk, M., Scherffius, A. M., Zahl, T., Wiegand, T., Pandey, S., Nichols, J. E., Hall, L., McVey, A., Lee, H. H., Wilkinson, R. A., Snyder, L. R., Jones, J. D., Koutmou, K. S., Santiago-Frangos, A., & Wiedenheft, B. (2022). Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic. Research square, rs.3.rs-1466718. https://doi.org/10.21203/rs.3.rs-1466718/v1 https://www.nature.com/articles/s41467-022-35445-5 | | | | |
