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Dear Jeannette ,
Check out our latest WCMC Newsletter!
- WCMC Outreach Core
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WCMC Metabolomics Courses | |
Get ready for an exciting return to in-person learning with WCMC's 1-week course! Our courses in metabolomics are tailored for researchers, postdocs, grad students, and scientists eager to deepen their expertise. Don't miss the early bird special which is until Feb 1, 2024! | |
Hands-on LC-MS Data Processing and Statistics 2024
(March 4-8, 2024 | In-Person)
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Date: March 4-8, 2024
Instructor-Led Course: In-person, ARC UC Davis
Time Commitment: 8 hours per day
Pace: Instructor-led
Level: Intermediate, ideal for participants who acquire metabolomics data and understand data acquisition
This 1-week course will feature hands-on training with real-world untargeted metabolomics data covering LC-MS data processing, compound identification, statistical analysis, network mapping, & data interpretation, including:
- Untargeted data processing and exercises on MS-DIAL.
- Exercises on the identification of unknowns by cheminformatics software workflows
- Data normalization and transformation with and without internal standards and quality controls
- Multivariate and univariate statistics
- Pathway mapping and enrichment analysis
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EARLY BIRD SPECIAL until February 1, 2024.......$2,500
Regular price from February 2, 2024..................... $3,000
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Bits & Bites 2024: 10-Part Short Course Series
(Jan - Dec 2024, Online)
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Join us for Bits & Bites 2024 — a flexible learning experience tailored for busy researchers seeking condensed yet impactful sessions. Now in its 4th year, this series continues to bridge the gap for those unable to commit to 1- or 2-week intensive courses. Craft your learning experience by selecting individual Bites à la carte or curate a comprehensive journey by mixing and matching courses for a fully immersive and well-rounded learning adventure. | |
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Bits & Bites # 02: Mass Spectrometry for Metabolomics
Date: February 8, 2024
Instructor: Dr. Uri Keshet, UC Davis
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Required Software: None
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Participant prerequisites: None
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Level: Introductory
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Short description of the course: Mass spectrometry (MS) has a crucial role in metabolomics as it’s one of the most widely used analytical techniques in the field. In this comprehensive yet short course, we will cover various MS systems and models like TOF, QQQ, and Orbitrap, understanding their application in metabolomics. You’ll also learn how to make informed decisions when selecting the right MS instrument, method, and parameters tailored to your research needs. Lastly, you’ll gain practical insights on how to optimize your workflow with tips and tricks for developing high-throughput MS methods, such as a short 5-minute method, designed for practical use in metabolomics research.
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Tuition: $175 per Bite, except for #10 (The price for #10 is $350 for approx. 8 hrs.)
Did you miss a Bite? You can still purchase the recordings and materials!
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WCMC Online Guest Lecture Seminars | |
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Date: February 28, 2024
Speaker: Francisco Tomás Barberán, Ph.D.
CEBAS-CSIC, Murcia , Spain
Title: "Metabolomics and gut microbiota metabolism of food bioactives: effects on human health"
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Date: March 13, 2024 Rescheduled
Speaker: Kirsten Overdahl, Ph.D.
The National Institutes of Health
Title: “Metabolomics Research in the NIEHS Intramural Research Program”
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Date: April 17, 2024
Speaker: Michael Witting, Ph.D.
Helmholtz Institute Munich, Germany
Title: "The use of information orthogonal to MS in metabolite identification – The role of RT, CCS and Co"
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We're excited to bring this new section to our newsletter, you can find detailed information about assays provided by the WCMC Service Core. | |
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The WCMC Service Core thank you for over 10,000 Samples for our Lipidomics (Complex Lipids) Assay in 2023!
Lipids are essential molecules that play diverse roles in cellular structure, function, and signaling. They are also involved in many metabolic pathways and diseases, such as diabetes, obesity, inflammation, and cancer. But how can you measure and analyze hundreds of lipids from different classes and subclasses in your samples?
The answer is lipidomics, a powerful tool that uses state-of-the-art mass spectrometry techniques to quantify and identify lipids from various biological matrices.
The West Coast Metabolomics Center (WCMC) at UC Davis offers a comprehensive lipidomics assay that can:
- Detect over 500 named lipids, and hundreds more unknown compounds, by matching their accurate masses, retention times, and MS/MS spectra to a lipids mass spectral library.
- Use 73 complex lipid internal standards to ensure accurate and reproducible representation of lipids in complex biological samples.
- Provide processed and curated data in Excel format that can be easily imported into various statistical and bioinformatics tools.
Ready to explore the lipidome of your samples and uncover novel insights into metabolism and disease?
Visit our website or contact us at metabolomics@ucdavis.edu to learn more about our lipidomics assay and how to get started.
Don't miss this opportunity to leverage the power of lipidomics for your research!
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- Mahajan, P., Fiehn, O., & Barupal, D. (2024). IDSL. GOA: gene ontology analysis for interpreting metabolomic datasets. Scientific Reports, 14(1), 1299.
- Wen, X., Fretts, A. M., Miao, G., Malloy, K. M., Zhang, Y., Umans, J. G., ... & Zhao, J. (2023). Plasma lipidomic markers of diet quality are associated with incident coronary heart disease in American Indian adults: the Strong Heart Family Study. The American Journal of Clinical Nutrition.
- Nemet, I., Funabashi, M., Li, X. S., Dwidar, M., Sangwan, N., Skye, S. M., ... & Hazen, S. L. (2023). Microbe-derived uremic solutes enhance thrombosis potential in the host. mBio, 14(6), e01331-23.
- Metz, T. O., Adkins, J. N., Armentrout, P. B., Chain, P., Chu, F., Corley, C. D., ... & Wishart, D. (2023). Decoding the Molecular Universe--Workshop Report. arXiv preprint arXiv:2311.11437.
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