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Philip De Jager, M.D., Ph.D.
Weil-Granat Professor of Neurology
Chief, Neuroimmunology Division
Department of Neurology
Columbia University Irving Medical Center
Dr. Philip De Jager is the Weil-Granat Professor of Neurology at Columbia University Medical Center, where he is the Chief of the Division of Neuroimmunology. The division consists of the Columbia Multiple Sclerosis Center and the Center for Translational & Computational Neuroimmunology. He focuses on characterizing and modulating the immune system in inflammatory and neurodegenerative diseases. He also serves as the Deputy Director of the Taub Institute for Research on Alzheimer’s Disease (AD) and the Aging Brain.
Using a deep integration of computational methods and rigorous molecular biology, he is defining the sequence of molecular events that leads a healthy immune system to become dysfunctional and ultimately engage the central nervous system as a target. He has delineated molecular networks and cellular communities in the CNS that lead to AD and multiple sclerosis (MS), with an emphasis on defining the basic biology of aging human microglia. His new Brain CASCADE initiative expands these efforts by generating large-scale multi-omic data in a spatially registered manner from human brain.
He has played an important role in dissecting the genetic architecture of susceptibility to MS and in developing tools and strategies with which to characterize the transition from health to MS. Working with the International MS Genetics Consortium, he continues to translate insights from genome-wide association studies into functional evaluations of genetic variation influencing risk of MS and other neurodegenerative diseases.
Overall, the goal of Dr. De Jager’s work as a clinician-scientist is to apply modern methods of human immunology, genomics, molecular genetics and computational biology to the understanding and treatment of common neuroinflammatory and neurodegenerative diseases.
Join in person at the Bornstein Family Amphitheatre, Main Pike 2nd floor, located on the left past the 45 Francis Lobby entrance or via Zoom https://partners.zoom.us/j/5823462701
*Lunch will be served for in-person attendees. Food is not allowed in Bornstein so please feel free to take a boxed lunch upon leaving the lecture.
Click here to learn more about the H. Richard Tyler, M.D. Memorial Lecture
Steps to claim CME credits for BWH Neurology Grand Rounds:
Send code QOCZUB to 1-857-214-2277.
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