April 2022 | IDDRC NEWS
Learn about the many resources available to you through your IDDRC membership, as well as current research, upcoming events, PI news, and other IDDRC related news. Get to know your world-class colleagues and stay on top of our center's many activities. Your IDDRC Directors, Drs. Scott Pomeroy and Mustafa Sahin

Infantile Spasms
Exploring Potential Collaborations to Improve Outcomes
Infantile Spasms (IS) is a unique early-life epilepsy with heterogenous etiologies, few treatment options, and significant developmental consequences.

  • Children with infantile spasms have a high risk of developing intellectual disabilities later in life.
  • Even without an underlying brain disorder or injury, children with IS are at risk of developmental delays and intellectual disabilities.
Featured Core
Human Neuron Unit | Clinical Translational Core
The HNC offers a full range of customizable services to investigators. These encompass patient sample procurement to generate iPSCs, differentiation of neurons, development of phenotypic models, and small molecule screening to identify compounds that modulate identified phenotypes.

With advances in iPSC technology, neurological disease modeling in a dish is now a physiologically relevant platform for advancing drug discovery in neuroscience.

Learning new methods for iPSC culturing can be challenging, time consuming, and cost prohibitive. The HNC seeks to facilitate your research efforts by 1) helping to set up platforms for labs who have yet to discover iPSC research, and 2) supporting labs with ongoing projects that need bandwidth assistance or reproducible access to neurons.


For more information email: Elizabeth Buttermore, PhD
Featured Equipment
Human Neuron Unit
Sartorius IncuCyteS3 live imager
The Sartorius IncuCyteS3 is a microscope housed within an incubator for live imaging. The instrument can hold 6 plates simultaneously and can image in bright field, green, and red fluorescent wavelengths. Imaging is set up with a user-friendly software interface so imaging can occur day or night on a pre-defined schedule without user intervention. 
Molecular Devices IXM-C
The Molecular Devices IXM-C is a powerful high content imaging instrument with confocal capabilities and a 7-color laser. The IXM-C can image multiple plate and slide formats and contains a live imaging chamber to control temperature and CO2 conditions for live cells. This microscope is connected to a spinnaker robot and hoteling incubator to enable screening of multiple plates without user interaction after initial setup. 
Meet our Investigators | Carol Wilkinson
Dr. Carol Wilkinson's lab is interested in understanding the neural mechanisms impairing language acquisition and cognitive development in children, especially those with disorders associated with intellectual disabilities.
 
Dr. Wilkinson's fascination with the brain has extended far beyond the lab into epic craft-making with her son.
Events and Seminars
Talks and seminars:
  • April 4: Helen Bateup, PhD, UC Berkeley
  • April 11: Brielle Ferguson, PhD, Standford University

  • April 12: Stephanie Rudolph, PhD | Albert Einstein College of Medicine | RSZ-TNC

Upcoming Conferences and Save the Dates:

AWARENESS DAYS

April is Autism Awareness Month
  • April 2: Autism Awareness Day
Kudos and Announcements
Kudos
To Dr. Nicole Ullrich, IDDRC member, who was recently featured in the Office of Faculty Development “Perspectives” Publication (page 2), and Dr. Carla Kim (page 4), External Advisory Committee member of our IDDRC.
Rosamund Stone Zander Clinical Translational Neuroscience Center Updates

New Website
The RSZ-TNC recently launched a new website. Check it out at http://rsztnc.org/.

NIMH T32 Fellows Application Period Open:
  • The T32 program is led by three co-directors (David Glahn, PhD, Psychiatry; Charles Nelson, PhD, Developmental Medicine Center; Mustafa Sahin, MD, PhD, Neurology) and a group of 14 highly skilled and successful training faculty from a diverse array of disciplines. 
  • Application deadline is April 15th.
  • More information: Fellowship Announcement | Program Description
Equity, Diversity, and Inclusion
Visit the new and improved Kirby EDI website to learn about the various initiatives taking shape. Contact Sylvia or Sable if you would like to learn more about getting involved.


Remember to cite the IDDRC in your publications by including:
We would like to thank the IDDRC funded by NIH P50 HD105351

The Random Act of Kindness Theme for April
Caring for the Environment
Earth Day is on April 22, 2022
Go on a nature walk and appreciate the wonders of the natural environment.