Wednesday, September 21, 2022

12:00PM-1:00PM

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https://partners.zoom.us/j/5823462701

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"Mechanisms of Neurodegeneration in Familial Alzheimer’s Disease"

Jie Shen, Ph.D.

Professor of Neurology, Harvard Medical School

Senior Scientist, Department of Neurology, Brigham and Women’s Hospital


Jie Shen is a Professor of Neurology at Harvard Medical School and Senior Scientist at Brigham and Women’s Hospital. Since 1998, she has directed a molecular neurobiology lab whose research focuses on revealing the pathogenic mechanisms of Alzheimer’s and Parkinson’s disease. Her lab uses a multidisciplinary approach to investigate the molecular and cellular mechanisms underlying degeneration of specific neural cells in the adult central nervous system. Through the generation and analysis of a variety of mouse models that carry mutations in the disease genes, her lab identified several early functional impairments that may trigger the pathogenic cascade leading to neurodegeneration.

 


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