Dear Researcher,

  Beta (β)-synuclein is the less-studied member of synuclein family. Beta-synuclein, a neuronal marker in brain, has recently gained more attention because of its increased level in the CSF and serum of patients with Alzheimer's disease (AD). 

  Biosensis has highly validated antibodies for all synucleins: alpha-, beta-, gamma- and pan antibodies (check out here).   

Left image: Expression of beta-synuclein (green) in mouse hippocampus section by IHC, which was detected with mouse antibody to beta-synuclein (M-2106) and co-stained with a rabbit antibody to neurofilament light (red)

Right image: The analysis of tissue homogenates mouse antibody to beta-synuclein (green, M-2106) by Western blot.

β-synuclein as an early diagnostic marker of AD 

In 2020, Halbgebauer et al. published an article on detecting β-synuclein as an early diagnostic marker of AD. They found that CSF β-synuclein levels were higher in the AD group than all other groups and concluded that monitoring loss of synaptic proteins could help to diagnose AD at the early stage.

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Best wishes for your research,



The Biosensis Team