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BioPharmGuy

The CPhI conference in Philadelphia has been a great success…for somebody. Not for me - I got Covid last weekend and had to cancel the whole trip. Been quarantined in my bedroom ever since. 

Hauled a desk in here and it’s become almost college dorm-like what with the lack of showers combined with eating ramen in bed, which is not something you do when you’re in your 40s and have a real house. (Unless you’re a weirdo, in which case, you do you.)

I've gotten some work done and binged the first season of The Wire, which definitely lived up to the hype. 

I’ve also been listening to music, as always. (and I do mean always. Last year I clocked 135,000 minutes on Spotify or 44% of waking hours)

Scrolled through my old lists/likes and as I did, I remembered this band I found years ago that no one listens to. They have three good songs and nothing else available to stream. Can’t find any info on the artist, "Buck, Buck, Buck". Has a Black Keys vibe. Check it out and let's see if we can't bump up their monthly listener count, which stands at 31.

Grift Into Unconsciousness

I’m debating removing our psychedelics category, mostly because there's no real path to profitability I have ever seen spelled out realistically and it's starting to look like one big grift whereby companies exist solely to convince retail investors (regular people who know nothing about the drug industry) to gamble on psychedelic stocks. I'm not sure BioPharmGuy should be helping that game.

Intellectual property in the psychedelic area is nonexistent for many of these companies and the products are still illegal across America, even if decriminalized regionally.

Perhaps more importantly, unlike most therapies, psychedelic treatments are reliant not only on the product, but also the setting/facilitation of the drug's administration. You can’t just prescribe shrooms and let people take them wherever and whenever they like. It doesn't work that way. So how can a small drug company scale a string of treatment facilities when a competitor will come along and get a similar product approved a month later competing margins down to nothing?

Of the 44 companies we list in the area, half are publicly traded. A 50% public company ratio is astronomical compared to any other sub-sector in the drug industry, but in this case it's even crazier because not a single one of these companies has an approved product. 

In fact, we list 2267 drug companies based in North America who do not have an approved product. 606 are publicly traded/owned, which translates to 27%. 

50% publicly owned for psychedelics is absurd and shows the field is reliant on amateur investors/gamblers.

-BPG

Companies Added & Removed

This week we added 19 companies and removed 49.

Best New Name:

Sisu Pharma

Worst New Name:

Syantra 

You Will be Missed:

Tiaki Therapeutics

You Won't be Missed:

X-37

Excel file of added/removed companies available on our downloads page.

Applied Therapeutics

Same crap different day in pharma. Here we have yet another company who failed a phase 3 trial, but is still going to submit a New Drug Application. 

It's always fun to read the company release in these situations, which comes across 99% positive and merely mentions in passing, "While statistical significance defined as a p value of <0.05 was not met on the primary endpoint..."

Failing to achieve significance on the primary endpoint is otherwise known as FAILURE.

Yes, they are publicly traded and also announced completion of a $30M stock sale along with this 'good' news. #notmymoney

Pick A Lane

About page: "Our lead product is in the cardiovascular area."

Portfolio page: "...dedicated to developing a therapy for the treatment of...sciatica"

A+!

Psycho Killers

We already went off on the psychedelic industry earlier, but here’s a company who named their page “Pipeline & IP” but the only IP mentioned as far as psychedelics go is another company’s technology. Brilliant.

Their stock (yes, they are public!) is down 90% over the past two years, so hey, can’t lose much more.

Cannabis Test Device

Given its prevalent use these days, we are far past a time where police should have a very easy way to test drivers for being under the influence of marijuana. OcuLogica is working on it. Their device relies on eye-tracking to detect those lazy weed eyes.

Conveniently, the article also includes a picture of the CEO seemingly about to fail a test. For science.

Mosanna Therapeutics

With a logo like this, you'd think the company would be called Sanna Therapeutics. But no, it's Mosanna.

That heart monitor output as the 'M', is passable and could even be cool. But the second scribble as an 'O' is just O-bnoxious.

It's a fine line between a pretty good logo and a pretty terrible logo, but this company figured out how to cross it. And did so in a scribbly, zig-zag pattern.

Mash Up

Here's a cool new company - Paratus is working on discovering new therapeutics by studying bat biology. Bats are the focus because they are a very old mammalian lineage and are known to harbor (and survive) many viruses that are seriously damaging to humans.

Then there's this other neat company who is working on lab-made, human milk as an alternative option to baby formula.

But dare we suggest merging these two companies into an entity that makes antiviral bat milk for the masses? Now that's an idea with legs...errrr, wings.

Go Team!

It can be cool for a company to congratulate their local sports team on the ol' home page. But when it’s been four years since that success and the team just fired their championship-winning coach, it might be time to remove the news item. 

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