The RNA Transcript, December 14, 2020
TODAY, Monday, December 14, 4:00–5:00 PM EST | U-M Center for RNA Biomedicine, RNA Innovation Seminar Series

"RNA-based regulation of viruses"
Narry Kim, Ph.D., Professor, School of Biological Sciences, Seoul National University Founding Director, RNA Research Center

A Washington Post video (duration 6'16") - December 8, 2020
How mRNA helped scientists create a COVID-19 vaccine in record time

Our RNA scientists, Alice Telesnitsky, Microbiology and Immunology, and Nils G. Walter, Chemistry, Biophysics & Biological Chemistry and co-director of the Center for RNA Biomedicine, explain how RNA research allows to save millions of lives with an RNA vaccine, and why it is possible to have a vaccine so quickly.
The Nobel Prize in Chemistry 2020 Lectures
by laureates E. Charpentier and J. Doudna
(duration: 1h)

"The CRISPR Cas9 has brought us into a new epoch
and in many ways are bringing the greatest benefits to human kind."
Monday, December 14, 6:30 pm EST | UMassMed RTI Science Café
ZOOM, Password: 989386

Dr. Vignesh Hariharan (Khvorova lab) and Dr. Manish Muhuri (Gao lab) discuss the strategies and challenges involved in overcoming the COVID-19 pandemic.
Tuesday, December 15, 3:00 pm EST | Harvard Medical School
ZOOM, Password: 759932

“Small RNAs in animal biology: a structural perspective”
Ian MacRae, Ph.D., Professor, Department of Integrative Structural and Computational Biology, The Scripps Research Institute
Wednesday, December 16, 9:00–10:00 am EST | RNA Collaborative Seminar Series, European Molecular Biology Laboratory (EMBL) hosting


“RNA regulates Glycolysis and Embryonic Stem Cell Differentiation via Enolase 1”

“Co-transcriptional RNP complex assembly in real-time: How transient protein-RNA interactions guide nascent ribosomal RNA folding”
Wednesday, December 16 through Saturday, December 19 | IEEE BIBM 2020 Workshop on Long Non-Coding RNAs Mechanism, Function, and Computational Analysis (BIBM-LncRNA)

Keynote Speakers: John Rinn, University of Colorado - Boulder, Rory Johnson, University of Bern, Switzerland, and Kaifu Chen, Harvard Medical School
Thursday, December 17, 2:00 pm | U-M Dissertation Defense

“Mechanism of Cytoskeleton Modification by Histone Methyltransferase SETD2”
Sarah Kearns, Chemical Biology, advisor: M. Cianfrocco & K. Verhey
Friday, December 18, 12:00 | U-M Neurology, Neurology/Neuroscience Research Seminar
Scan the QR to register
 
“RNA-Protein Homeostasis in Healthy and Diseased Neurons”
Francesco Lotti, Ph.D., Assistant Professor, Department of Pathology & Cell Biology, Columbia University Medical Center
January 6–8, 2021 | Intersections Science Fellows Symposium
This multi-institutional symposium will showcase the work of mid- to late stage postdocs in biomedical science on January 6-8th, 2021, virtually. This exciting symposium aims to showcase the science of outstanding postdocs specially those who are from backgrounds historically underrepresented in academia to advance diversity, equity and inclusion in academic science. 
 
For more information, please visit our website and follow us on Twitter @InterSciFellows.
For any questions, please contact: info@intersectionssciencefellows.com. 
 
Contact Elisabeth Paymal for press releases and blog articles of your upcoming publications. MORE INFORMATION

Our members' publications are available through Altmetric. Five queries are currently available: "RNA," "microRNA," "Transcriptome," "Translation," and "Molecule." Please make sure to have at least one of these key words in your title or abstract. Below is a recent highlight.
High-throughput screening to discover inhibitors of the CarD·RNA polymerase protein–protein interaction, Stefan, M.A., Velazquez, G.M. & Garcia, G.A. in Mycobacterium tuberculosis. Sci Rep 10, 21309 (2020). https://doi.org/10.1038/s41598-020-78269-3

Significance
We expect that the development of a new and improved anti-TB compound with a novel mechanism of action will relieve the burden of resistance. This CarD FP assay is amenable to HTS and is an enabling tool for future novel therapeutic discovery.

Key Points
  • An innovative digital assay technology enables rapid, point-of-care measurement of multiple protein biomarkers in blood.
  • Continuous monitoring of protein blood biomarker profiles is demonstrated for critically ill human patients with a digital assay.
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