DSI's wireless small animal telemetry system allows data acquisition from conscious, freely moving laboratory animals, providing stress-free data collection while enhancing animal welfare.
The AB&P Core (Physiology group) can acquire a plurality of physiologic signals including EEG, ECG, EMG, core temperature, and actigraphy to quantitatively assess seizures, circadian abnormalities and physiologic signatures across the EEG frequency spectrum. 2-channel wireless transmitters also permit simultaneous recording of cortical EEG and neck EMG for sleep analysis.
This state-of-the-art setup enables a strong set of physiological assays to evaluate novel CNS pharmacotherapies in preclinical disease models. The Core also provides expertise and end-to-end services for rodent surgeries, dosing compounds, collecting samples for pharmacokinetic analysis, and conducting high-throughput data analysis.