The RNA Transcript, October 18, 2021 |
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TODAY, Monday, October 18, 4:00 pm ET, ZOOM REGISTRATION | University of Michigan Center for RNA Biomedicine, RNA Innovation Seminar Series
“Imaging single-mRNA translation dynamics in living color”
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Introducing Chase Weidmann, Ph.D.,
our second RNA Faculty Scholar and
Assistant Professor, Biological Chemistry, Medical School
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Chase Weidmann had three goals for a career: do something “cool,” improve the lives of other people, and, of course, be able to support himself. Read more.
"We are interested in how cellular signals are propagated through interaction networks at the RNA-protein interface, and how these networks malfunction during cancer and disease. In cancer cells, changes in RNA-binding protein stoichiometry and modification status reorganize the interaction networks of noncoding RNAs, resulting in altered functions. Our vision is to leverage RNA and protein sequencing technologies to characterize these altered interaction network profiles in order to generate novel therapeutic strategies that target the RNA-protein interface."
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Congratulations to Janet Smith, member of our Strategic Advisory Board, on receiving a Distinguished University Professorship award!
With this award, the Board of Regents recognizes senior faculty for exceptional scholarly or creative achievement, national and international reputation, and superior records of teaching, mentoring and service. Faculty selected for the recognition, in consultation with the dean of the school or college in which he or she holds an appointment, name the professorship after a person of distinction in his or her field of interest.
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Tuesday, October 19, 3:00 pm ET, ZOOM | Harvard Medical School, Initiative for RNA Medicine Seminar
“Antiviral responses to endogenous RNA in C. elegans”
Sylvia Fischer, Ph.D., Assistant Professor of Pediatrics (Infectious Disease), Boston Children’s Hospital, Harvard Medical School
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Wednesday, October 20, 9:00 am ET, ZOOM registration | RNA Collaborative Seminar Series hosted by Helmholtz Institute for RNA-based Infection Research (HIRI), Germany
“CRISPR-Cas systems and the dilemma(s) of adaptive immunity”
"Uncovering host-pathogen interaction modalities using single-cell RNA-seq and RNA metabolic labeling"
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Wednesday, October 20, 8:00 am–6:00 pm PDT | hosted by Syntego
"2nd annual World CRISPR Day event," hosted by Synthego. An exceptional event where we’ll share, listen, and learn about the latest advancements in CRISPR from the industry’s leading experts.
Keynote speaker: Fyodor Urnov, Ph.D., Director for Technology and Translation at Innovative Genomics Institute, Professor of Genetics, Genomics, and Development at University of California, Berkeley
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Monday, October 25, 12:30–5:30 pm, Rackham Graduate School | University of Michigan, Drug Discovery
"First Annual Drug Discovery Symposium"
The Symposium aims to highlight success stories from the drug discovery community at the University of Michigan. The symposium will give faculty and trainees a chance to share best practices and network with others involved with drug discovery research on campus.
With Anna Schwendeman, Ph.D., Roger Cone, Ph.D., Shaomeng Wang, Ph.D., Lola Eniola-Adefeso, Ph.D.
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Tuesday, October 26, 12:00–1:00 pm ET, in-person: 3330 MS I, ZOOM | University of Michigan, Biological Chemistry
"Know Thy Enemy: Making CRISPR Memories"
Hosts: Yan Zhang and Nils Walter
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January 3–6, 2022, St. Petersburg, Florida | The RNA Society
6th Conference on Regulating with RNA in Bacteria & Archaea — CRISPR systems, small noncoding RNAs, riboswitches, transcriptomics, host-pathogen interactions, and more.
The deadline for early registration and submission of oral abstracts is October 31, 2021; poster abstracts will be accepted through November 15, 2021.
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For press releases and blog articles about your upcoming top journal publications, please
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Our members' publications are available through Altmetric. Five queries are currently available: "RNA," "microRNA," "Transcriptome," "Translation," and "Molecule." Please make sure to have at least one of these key words in your title or abstract. Below is a recent highlight.
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Rapid kinetic fingerprinting of single nucleic acid molecules by a FRET-based dynamic nanosensor, Kunal Khanna, Shankar Mandal, Aaron T. Blanchard, Muneesh Tewari, Alexander Johnson-Buck, Nils G.Walter, Biosensors and Bioelectronics, Volume 190, 15 October 2021, 113433, https://doi.org/10.1016/j.bios.2021.113433
Highlights:
• Amplification-free single-molecule kinetic fingerprinting identifies diverse disease biomarkers.
• A dynamic DNA nanosensor generates kinetic fingerprints via intramolecular single-molecule FRET.
• iSiMREPS in 10 s detects biomarkers with a limit of detection of ~3 fM in 1,000,000-fold WT excess.
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13 post-doctoral researcher positions
at FP-Dynamo, Paris, France
The COFUND FP-DYNAMO-PARIS programme offers a unique interdisciplinary environment and a fundamental research initiative in the centre of Paris to train the scientists of tomorrow in the field of physico-chemical biology. The goal of the research programme is to integrate knowledge on gene expression, structural and membrane biology, and bioenergetics in bacteria, chloroplasts and mitochondria in the general context of improving our understanding of the biogenesis of energy-transducing membranes. These studies will involve cutting-edge technologies including structural biology (NMR, X-ray crystallography and CryoEM), RNA se-
quencing, mass-spectrometry, synthetic biology, microfluidics, computational modelling and visualization.
Post-doctoral fellows will have the opportunity of developing their research projects in a dynamic scientific environment covering three main research themes:
i) RNA biology from bacteria to chloroplasts,
ii) membrane system dynamics and
iii) computational modelling of molecular assemblies.
They will benefit from the supervision of internationally-recognised experts in their fields, a world-wide network of renowned institutions, cutting-edge research infrastructure and state-of-the-art technical know-how that will allow them to hone their scientific skills, make themselves known and increase their competitiveness on the labour market.
Specific training will be proposed to ERs through attendance of the EMBO course on “Laboratory Leadership for Postdocs” included in a retreat in Padua, and involvement in dedicated complementary soft skill training events.
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034407
A second call for candidacies will open in January 2022 with 8 additional post-doc positions.
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