The CCTS Investigator
Advancing Today's Discoveries To Improve Health For All
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What's New in Translational Science? |
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Scientists at NIH [external link] and Massachusetts General Hospital in Boston [external link] have uncovered a potential new approach against liver cancer that could lead to the development of a new class of anticancer drugs. In a series of experiments in cells and mice, researchers found that an enzyme produced in liver cancer cells could convert a group of compounds into anticancer drugs, killing cells and reducing disease in animals.
Image Courtesy of NCATS
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Save the Date
Appalachian Translational Research Network Annual Health Summit
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The 13th Annual Appalachian Translational Research Network (ATRN) Health Summit.
October 5-6, 2023
Hosted by West Virginia University, Morgantown, WV.
More Information Coming Soon
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The CCTS has begun the process of updating our website and we want to hear from you!
How often do you use our website? Is it easy to navigate? What is missing from our website that you would find helpful?
The User Experience Survey will take less than five minutes to complete and we value your feedback to help make the CCTS website more useful to our members.
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Steps to Request IT Resources for Research |
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Researchers interested in using IT resources must submit all IT requests through the Research Shareholder Group (RSG). Requests must include the following before being reviewed by the RSG:
- The Ohio State University Wexner Medical Center Risk Assessment
- IRB approval status
- Funding status
- Security status
- Specific technology request
*Please note that an Ohio State Wexner Medical Center Risk Assessment must be completed before submitting a request to add a software system for research. It is important to start the Risk Assessment process early as it will take additional time.
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Investigator-Initiated Multi-Center Research Capacity Survey |
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The Ohio State University Center for Clinical and Translational Science is seeking information about interest in the design, implementation, leadership and funding of investigator initiated, multi-center clinical research studies and trials, outside of cancer research.
Please take a few minutes to answer the survey linked below. Your responses will help us to better understand our research community. It should not take more than three minutes to complete.
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ResearchMatch is a complimentary tool for researchers to connect directly with individuals interested in participating in clinical trials.
Researchers, if you are interested in learning how you can use ResearchMatch, a complimentary recruitment method, to help you recruit participants for your study, please email the recruitment and retention manager, Mary Becker [email], and the recruitment and retention coordinator, Clara Kalis [email], at the CCTS for more information on how to get started.
If you are interested in having someone from the CCTS Recruitment and Retention program speak at your staff and/or departmental meetings about our services and how we can help you meet your clinical trial recruitment goals, please contact Mary Becker [email].
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NIH Request for Information
Re-envisioning U.S. Postdoctoral Research Training and Career Progression within the Biomedical Research Enterprise
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The NIH is seeking input from the community, particularly trainees, early-stage faculty and others invested in the biomedical workforce, about challenges faced by the postdoctoral trainee community. An NIH Advisory Committee to the Director Working Group [external link] has posted a Request for Information [external link] where you can share insights on issues effecting and possible solutions to the recent decline in postdoctoral trainees.
Your responses will be used to help develop recommendations to address this problem which impacts U.S. competitiveness in biomedical research and innovation.
The RFI closes on April 14, 2023.
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This month, meet April Green!
Q: What is your role at CCTS?
A: CCTS Regulatory Program Manager, in this role I provide guidance and education on IND and IDE submissions to the FDA, assist with prior approvals for research protocols funded by NCATS, complete protocol and consent form reviews/consultations and support the CCTS Data Safety Monitoring Board.
Q: How do you think the CCTS is impacting medicine?
A: By assisting with the process to turn research into discoveries, the CCTS helps to improve the health of individuals and the public.
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The CCTS Funding Opportunities and Events |
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If you are an early-stage investigator planning to write an NIH K grant or if you have mentees or colleagues interested in pursuing a K grant, please forward this information to them.
The Launch to K program assists biomedical scientists in launching their academic careers by writing a K series NIH career development grant proposal. Only six participants will be accepted in the workshop.
The individual components of a K series career development award (or comparable foundation grant) will be discussed through a step-by-step process over the 12 two to two-and-a-half-hour meetings. The heart of the workshop will be peer-to-peer reviews of biweekly writing assignments of the grant components: candidate, mentorship plan, career development training plan, the approach and scientific environment and institutional support. Experienced NIH-funded investigators will assist in guiding the group and illustrating the various components of a K award from a grant reviewer's perspective, with assistance from recent successful K awardees.
Launch to K will meet every two weeks. It is tentatively set to meet on Tuesday afternoons from 2 - 4 or 4:30 p.m., from approximately May 9 to September 26, 2023. Participants are expected to attend at least 80% of the sessions.
Application Deadline: April 3, 2023, 11:59 p.m.
Contact:
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Save the Date for the second annual Preventative Health of Adipose Tissue (PHAT) Symposium, April 14, 2023, hosted by the Center for Preventative Health of Adipose Tissue and the Davis Heart and Lung Research Institute (DHLRI).
And Save the Date for the inaugural Translational Research in NeuroMetabolism (TRINS) Symposium, April 15, 2023, hosted by the Department of Neurosurgery.
These interdisciplinary regional events are open to any researchers whose work intersects with the study of adipose tissue, with the goal of bringing together new research teams and collaborations with stimulating discussions around the future of adipose tissue research across the basic, translational and clinical spectrum.
When: April 14, 2023, 8:30 a.m. - 4 p.m. EST and April 15, 2023, 8 a.m. - 4:30 p.m. EST
Where: Davis Heart and Lung Research Institute
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Let's get to work on the Anti-Bias Checklist. For this inclusive teaching workshop, please bring one to two curricular items to evaluate. Facilitated by faculty and instructional designers in the College of Medicine, participants will work in small faculty groups. Participants will be able to: recognize best practices to support inclusive teaching, examine curricular items that can be reviewed by the Upstate Bias Checklist, interpret the results of the Upstate Bias Checklist and identify the components of the teaching materials that will require revision.
When: April 7, 2023, 12:30 - 2 p.m. EST
Where: Atwell Hall, Room 251
WOW Your Audience With Your Next Presentation
Learn practical and creative use of Microsoft 365 Powerpoint to create effective presentations that will grab your audience attention and meet accessibility standards.
When: April 14, 2023, noon -1 p.m. EST
Where: Online
In this in-person FAME program, you will go behind the scenes to watch and participate in a mock departmental promotion and tenure committee meeting. Participants will be able to read sample dossiers, observe how different faculty tracks and paths are evaluated and vote to see if you would promote these fictional faculty members.
When: April 26, 2023, 3 - 5 p.m. EST
Where: Meiling Hall, Room 160
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The global aging population is witnessing an alarming rise in the number of cases of eye disease, with retinal issues affecting the lives of over 250 million people worldwide. Patients with vision threatening conditions such as macular degeneration may receive injections in their eyes as often as every month to prevent blindness. While effective, maintaining these treatment regimens creates a huge burden for patients and their caregivers, as well as for healthcare providers.
When: April 12, 2023 noon-1pm EST
Where: Online
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Comparative Translational Research: Modeling Disc Degeneration
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The Ohio State Center for Clinical and Translational Science Comparative and Translational Medicine program presents a series of seminars highlighting how the use of spontaneous animal models of disease can create an integrated platform for collaborative research, therapeutic interrogation, cross-disciplinary training and outreach across Ohio State, Nationwide Children's Hospital and partners.
When: April 20, 2023, noon-1 p.m.
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The next scheduled session will be 'Features of REDCap Version 13'. This Grand Rounds will be an overview of the upcoming REDCap upgrade to 13.4.x and review new features available with the upgrade in April.
When: April 11, 2023, 11 a.m. - noon
Where: Online
This level of training is appropriate for individuals who have used REDCap and are comfortable with building forms or have attended or watched Design 2: Basics training. This session is the most advanced design session available. It reviews the most recent features of advanced REDCap, as well as importing data, randomization, advanced action tags, external modules, multi-language module and more!
When: April 26, 2023, noon-1 p.m. EST
Where: Online
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The Center for Clinical and Translational Science is presenting its Research Mentoring Workshop on Wednesday, May 9 and 11, 2023, (must attend both sessions) from 1 - 3 p.m. on Zoom.
The facilitators are Jennifer Garvin, PhD and Lisa Christian, PhD.
The two-session workshop uses a case-based, discussion-oriented curriculum designed by the Center for the Improvement of Mentored Experience in Research (CIMER) that is theoretically grounded, evidence-based and culturally responsive. The training is designed to help faculty who mentor early career researchers, especially junior faculty, to become more effective research and career mentors.
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Seeking Breakout Room Discussions
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A symposium featuring faculty research supported by the Ohio State Department of Biomedical Informatics, Center for Biostatistics, Secondary Data Core, curated for an audience of clinicians and researchers. Research professionals will present on their experience and overall expertise using secondary data to answer important questions throughout multiple areas of study.
When: May 19, 2023, 10 a.m. - 3 p.m. EST
Where: Online
Seeking Breakout Room Discussions
This survey will help us determine which secondary databases/tools people are most interested in discussing during the Secondary Data Symposium's breakout sessions.
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700 Children's® – A Blog by Pediatric Experts
Nationwide Children's Hospital
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Each person’s skin is unique, so scleroderma looks different for every patient. A child or young adult may start out with a small area of affected skin that changes in texture. Some people describe the skin as becoming tighter, firmer, more stretched or thickened. The affected area may lighten, darken or develop a red border.
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External Funding Opportunities and Events |
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REDCap Office Hours via Zoom
When: Every Monday, 11 a.m. - 1 p.m.
Every Wednesday, 1 p.m. - 3 p.m.
REDCap Training Resuming
The Ohio State Center for Clinical and Translational Science, in coordination with the Department of Research Information Technology (RIT), conducts monthly training sessions via Microsoft Teams.
There are four modules of training based on the role(s) a user will have within REDCap. Registration for each session opens two weeks prior to the session.
This level of training is appropriate for projects that have questions about collecting Electronic Informed Consent. We will be discussing the current eSignature rules and regulations, the new workflow for requesting the eConsent Extension (fee for service) and the implementation of eConsent Extension DIY.
Great for people who cannot attend the Grand Rounds session.
When: Last Wednesday of each month, noon - 1 p.m.
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This month's topic is REDCap Creative Uses 2.0
The monthly topics will be posted on the REDCap blog. [external link]
Advance registration is requested.
When: Second Tuesday of each month, 11 a.m. - noon
Where: Zoom
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Read about the latest translational science news, opportunities and announcements in the latest edition of the NCATS e-Newsletter and the NIH's Weekly Funding Notice.
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Learn more about PCORI through their blog, video room, news releases and other resources.
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Visit our website [external link] or click on the social media icons below to be directed to our social pages (Facebook, Twitter, Youtube).
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Publications supported by the CCTS are required to cite The Ohio State University Center for Clinical and Translational Science.
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