Initiative for MPTs: Partner Update

Initiative for MPTs:

Partner Update

August 2020

Greetings Colleague,

We hope this message finds you keeping well and healthy as we all work to safeguard our families and communities during these difficult times.

Despite the current challenges posed by the global pandemic, the field of multipurpose prevention technologies (MPTs) continues to evolve and expand. After a transition process within the IMPT Secretariat in early 2020, we are grateful to continue our work to advance the MPT agenda.

Below are some recent highlights and updates from the IMPT Secretariat, which include links to recent publications and other new resources relevant to MPTs. We also invite you to visit our resource center and archives to access more materials that may be of interest to you. As always, we encourage you to share any MPT-relevant resources with us that you would like circulated to the IMPT Network.

Sincerely,

IMPT Secretariat Staff

Photograph_ Ian Schneider https___unsplash.com__goian

Upcoming Virtual Events

Join Director and Co-Founder of the IMPT, Bethany Young Holt, PhD, MPH, in conversation with the Male Contraceptive Initiative (MCI) on Thursday, 27 August 2020, 8am PDT / 11am EDT / 5pm CEST. This webinar, entitled "Discussing Multipurpose Prevention Technologies (MPTs) & Male Contraception," is part of MCI's Lemonade Stand Discussion Series. Please register today to save your spot!

We will be moderating a round table on contraception at this year's virtual Women's Health Innovation Summit (WHIS) on Wednesday, 9 September 2020 at 10:30am PDT. Registration is available on the event website & additional details on this session will be posted shortly. Don't miss presentations by other IMPT network partners, including Daré Bioscience, Evofem Biosciences Inc., Bill & Melinda Gates Foundation, Reproductive Health Investors Alliance, among others.

Here at the IMPT, we anticipate launching our own MPT webinar mini-series in the fall of 2020, covering topics including vaginal microbiome, MPT delivery devices, and socio-behavioral/market considerations for MPT development, among others. Stay tuned!

MPT Database

The IMPT's online MPT Product Development Database has been updated, reflecting the full pipeline of MPT candidates currently in development and actively funded as of June 2020.

For those interested, our revised inclusion/exclusion criteria for the database are also available online.

Journal Articles

Apologies for cross-posting. We want to make sure everyone in our network is aware of the following articles.

Two open access manuscripts co-authored by the IMPT were published in the Contraceptive Special Issue of the journal Biology of Reproduction, which is now available in print and online:

"Bridging the gap: Advancing multipurpose prevention technologies from the lab into the hands of women." A commentary calling for a product neutral panel of experts to help guide and advance the MPT field, co-authored by colleagues from FHI 360, Magee Women's Research Institute, UCSF, WHO, and the IMPT. 27 May 2020.
"Towards a roadmap to advance non-hormonal contraceptive multipurpose prevention technologies: Strategic insights from key stakeholders." A manuscript outlining current gaps and strategic action areas to advance non-hormonal contraceptive MPTs. 10 June 2020.

Stemming from the November 2019 NICHD Contraceptive Development Meeting, which focused on the development of non-hormonal contraceptives including MPTs, several of our IMPT partners also published manuscripts in the BOR Contraceptive Special Issue:

"Preclinical contraceptive development for men and women." Daniel S Johnston, Erwin Goldberg. 03 June 2020. Open access.
"The new contraceptive revolution: Developing innovative products outside of industry." Rebecca L Callahan, Neha J Mehta, Kavita Nanda, Gregory S Kopf. 09 May 2020. Open access.
"The role of team science in the future of male contraception." Heather L Vahdat, Kevin Shane, Logan M Nickels. 29 May 2020. Open access.
"Development of multipurpose technologies products for pregnancy and STI prevention: Update on polyphenylene carboxymethylene MPT gel development." Mary Weitzel, Barbara Best North, Donald Waller. 29 May 2020. Open access.
"Engineering monoclonal antibody-based contraception and multipurpose prevention technologies." Deborah J Anderson, Joseph A Politch, Richard A Cone, Larry Zeitlin, Samuel K Lai, Philip J Santangelo, Thomas R Moench, Kevin J Whaley. 08 June 2020.

Resources

Please visit our MPT Resource Center to find other MPT-relevant publications. Here are some resources that partners have shared with us in recent months:

Two new research briefs from the Tablets, Ring, Injections as Options (TRIO) study, conducted with young women in Kenya and South Africa to understand their perspectives on future MPTs. Published and shared by RTI International's Women's Global Health Imperative.
New journal article shared by Evofem Biosciences Inc., published in Contraception: X: "A novel vaginal pH regulator: results from the phase 3 AMPOWER contraception clinical trial." Michael A Thomas, B Todd Chappell, Bassem Maximos, Kelly R Culwell, Clint Dart, Brandon Howard. 01 June 2020.
New journal article shared by Population Council, published in BMJ Sexual & Reproductive Health: "Estimating the market size for a dual prevention pill: adding contraception to pre-exposure prophylaxis (PrEP) to increase uptake." Lorna Begg, Rebecca Brodsky, Barbara Friedland, Sanyukta Mathur, Jim Sailer, George Creasy. 31 July 2020.

Contact us if you and/or your colleagues are attending any upcoming meetings where MPTs will be featured. We're happy to provide materials to help enhance your presentations. We'd also love to include in our Resource Center any materials you have to share from recent MPT relevant events.

Visit MPTs101.org and theIMPT.org, or click below

for more resources on MPTs.

IMPT Secretariat

1750 Howe Avenue, Suite 550
Sacramento, CA 95825

[email protected]

theIMPT.org

MPTs101.org

The Initiative for Multipurpose Prevention Technologies (IMPT) is a project of CAMI Health, a social impact organization dedicated to improving the health of women and their families worldwide. CAMI Health is housed at the Public Health Institute (PHI).