Penn State National Science Foundation Center for Health Organization Transformation
(Penn State CHOT) - An Industry-University Cooperative Research Center
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Thank you for your hard work and support in 2020. Best wishes for a wonderful holiday and a happy new year. The best is yet to come in 2021!
Sincerely,
Hui Yang, Penn State CHOT site director
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Chris DeFlitch, Penn State Health vice president and chief medical information officer and CHOT co-principal investigator, answered critical questions about COVID-19, vaccines, and the future of telehealth at Penn State.
1. Are we learning how to better treat the COVID-19 virus?
| 2. Who should receive the COVID-19 vaccine and why is it so important?
| 3. If someone had COVID-19, do they still need to get the vaccine?
| 4. What is the future of telehealth at Penn State Health?
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Cross recurrence analysis for pattern matching of multidimensional physiological signals
Adam Meyers, Mohammed Buqammaz, and Hui Yang published a new paper in Chaos: An Interdisciplinary Journal of Nonlinear Science. Full text can be accessed via the DOI link:
The authors developed a novel cross recurrence analysis (CRQA) method for pattern matching of physiological signals. CRQA, based on the cross recurrence plot (CRP), is an effective method to characterize and quantify the nonlinear interrelationships between a pair of nonlinear time series. It allows the flexibility of reconstructing signals in phase space and to identify different types of patterns at arbitrary positions between trajectories. These advantages make CRQA attractive for time series data mining tasks, which have been of recent interest in the literature. However, little has been done to exploit CRQA for pattern matching of multidimensional, especially spatiotemporal, physiological signals. In this work, the authors present a novel methodology in which CRQA statistics serve as measures of dissimilarity between pairs of signals and are subsequently used to uncover clusters within the data. This methodology is evaluated on a real dataset consisting of 3D spatiotemporal vectorcardiogram (VCG) signals from healthy and diseased patients. Experimental results show that the length of the longest diagonal line in the CRP yields the best-performing clustering that almost exactly matches the ground truth diagnoses of patients. Results also show that the authors' proposed measure, which characterizes the maximum similarity between signals over all pairwise time-delayed alignments, outperforms all other tested CRQA measures (in terms of matching the ground truth) when the VCG signals are rescaled to reduce the effects of signal amplitude.
Below is a video of an invited presentation by the authors at the 2020 INFORMS annual meeting.
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Prediction and intervention models for combating the opioid crisis
Haedong Kim, a CHOT scholar, gave a poster presentation of his research project on the opioid epidemic during the Penn State industryXchange 2020 virtual poster session. Here is the link to download the poster.
A Penn State CHOT team is working on developing prediction models of opioid overdose risk based on regional and temporal characteristics of social determinants such as median household income, occupational distribution, or unemployment rate. The research proposes to develop new Gaussian Process-based spatiotemporal models to investigate the intrinsic correlation associated with regions and time. Ultimately, the researchers aim to develop a simulation model of the supply chain of opioids by integrating the risk prediction models and policy optimization methods. |
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CHOT is a sponsor of INFORMS ICSS 2020, with CHOT site director Hui Yang and CHOT faculty member Robin Qiu serving as conference co-chairs. The ICSS 2020 program committee is committed to organizing a quality conference with diverse participants who will share their visions, knowledge, and experience in service science research, education, and applications. The conference theme is AI and Analytics for Public Health, aimed at promoting the development of healthy and strong communities where we live, work, learn, and play, and protecting the health of people and communities nationally and internationally.
You are invited to attend the ICSS 2020, which will be held virtually Dec. 19-21. Please click here to visit the online program page for the schedule of talks and corresponding Zoom links to attend.
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The fifth issue of the annual Penn State Harold and Inge Marcus Department of Industrial and Manufacturing Engineering magazine has been published. Click here to read the magazine. This issue introduces works by industrial and manufacturing engineering faculty, including CHOT faculty members, to fight the coronavirus pandemic. Other health care-related research projects are also featured, such as the investigation on side effects of drug-drug interactions and recurrence analysis of sensing data of the human heart.
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Joonha Chang is a third-year Ph.D. student focusing on operations research. He received a bachelor's degree and master's degree in applied mathematics. Chang is interested in finding a fundamental solution to a problem, whether in theory or in modelling. In CHOT, he is seeking to find a model for estimating and optimizing the actions on the opioid epidemic in the U.S. The opioid epidemic has become a drastically emerging issue, and many uncertainties lie within it due to the illicit and uncertain circumstances of opioid drugs. Many researchers have attempted to find a resolution for the epidemic, but a mathematical modeling to predict the usage of drugs and its effects has yet to be explored. Through this research, Chang will be able to propose a new model that can predict the infection of the epidemic and propose a corresponding solution in terms of prevention, medication, and policy.
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Health IT + Revenue Cycle Management Virtual Forum
Feb. 9-21, 2021
Virtual Conference
Health IT is taking center stage as health systems aim to transform care delivery. The pandemic accelerated virtual care, digital offerings, and data analytics adoption, and now health systems are taking a step back to refine their processes for secure and sustainable operations in the future. Health system executives are also keeping a close eye on the revenue cycle as margins tighten. Innovation in care delivery and cost savings opportunities will remain essential. Please register and check agendas here.
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Check out the CHOT website for information about our new projects and exciting activities.
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If you have any exciting news that you would like to feature in our CHOT newsletter, please submit it to Haedong Kim, newsletter editor, at huk344@psu.edu.
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