Developing & advancing new HP MRI technology to better
detect, understand, and treat human diseases worldwide
Clinical Translation of HP 13C MRI for Unmet Needs
In 2013, the first-in-human clinical trial of HP 13C MRI at UCSF was published demonstrating the safety, feasibility and ability to detect occult prostate cancer not visualized on standard-of-care MRI. Since then 14 sites around the world, have applied this molecular imaging technology to human studies to advance clinical investigations of diseases as reported in the 59 publications with human HP C-13 MRI data thus far. The number of publications is expected to increase rapidly with more clinical sites applying this technology for clinical investigation. 

As we begin 2022, we celebrate these milestones and take a deeper look into recent presentations, tutorials, and publications in HP 13C MRI human research. Stay tuned for our in-person live 2022 HMTRC Workshop that will provide training and discussions on the technical aspects and hands-on experience on how this technology is implemented for clinical research. A link to the Workshop Brochure is listed below.

Best regards,

The HMTRC team & Collaborators

Presentation Highlights on Human Research
Visit or re-visit some recent video presentations on
advances in HP 13C MRI Research for Clinical Translation.
Call for Seminar Presenters
We are currently looking for March presenters for our International HP C-13 MRI Seminar. Present new findings, publications, or other work in preclinical and human research. Presentations are 25 minutes with a
5-minute Q &A. Email us at [email protected].
The HMTRC Website. What's New?
Human Research 13C List
Now you can find a list for all HP 13C MRI Human Research Studies in one place. Visit our website to learn, stay updated, or get inspired.
Clinical Center Review Articles
 Check out these review articles to
inspire & drive your basic and clinical research.

Hyperpolarized 13C MRI Data Acquisition and Analysis in Prostate and Brain at University of California, San Francisco

Crane JC, Gordon JW, Chen HY, Autry AW, Li Y, Olson MP, Kurhanewicz J, Vigneron DB, Larson PEZ, Xu D

Fast Imaging for Hyperpolarized MR Metabolic Imaging

Gordon JW, Chen HY, Dwork N, Tang S, Larson PEZ


Hyperpolarized 13C MRI: State of the Art and Future Directions

Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB


Hyperpolarized 13C MRI: Path to Clinical Translation in Oncology

Kurhanewicz J, Vigneron DB, Ardenkjaer-Larsen JH, Bankson JA, Brindle K, Cunningham CH, Gallagher FA, Keshari KR, Kjaer A, Laustsen C, Mankoff DA, Merritt ME, Nelson SJ, Pauly JM, Lee P, Ronen S, Tyler DJ, Rajan SS, Spielman DM, Wald L, Zhang X, Malloy CR, Rizi R
HMTRC 2022 In-Person Workshop
If you haven’t done so already, mark your calendars for our 2022 Hyperpolarized 13C Technology Development Workshop in San Francisco on March 17th-18th. In this workshop get hands on experience on application of HP 13C MR in Pre-clinical & Translational Research. Visit our brochure to learn about topics covered, how to register for the workshop, hotel accommodations, and more.
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The Hyperpolarized MRI Technology Resource Center (HMTRC) is supported by the National Institute of Biomedical Imaging and Bioengineering
(NIH P41EB013598) and focuses on the development and dissemination of new advances in dissolution DNP techniques and instrumentation, specialized data acquisition methodology, and analysis software for biomedical research. 
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