Your COVID-19 Questions & Answers
Responses from Tom Belhorn
Q:
I read that studies show antibody to COVID-19 might be gone a few months after infection. Does that mean everyone can get infected again in a few months? How does that impact testing and precautions?
A:
The article published in Nature Medicine last week about immunologic assessment in asymptomatic SARS-CoV-2 infections has again focused discussions on duration of immunity after infection. First of all – we need more data. The authors did demonstrate in their smaller population more rapid decrease of antibody especially compared with the original SARS and MERS-CoV. Even if this finding is verified by others, one must remember immunity does not always equate with circulating levels of antibody (lower levels can be protective, there is immunity via T cell responses, etc.). But this data, when clarified, will impact all management decisions where duration of immunity is important – decisions on timing of re-testing, needed precautions, vaccine studies, et al. Again, more data is needed and no changes in management protocols are needed at this time. Stay tuned…