The RNA Transcript, October 24, 2022

Job Opportunities

Join the University of Michigan Center for RNA Biomedicine! 

A fabulous community of faculty, students & researchers. We have two open positions in our team:

RNA Center Program Manager: https://careers.umich.edu/job_detail/225431/rna-center-manager

Administrative coordinator: https://careers.umich.edu/job_detail/225397/administrative-coordinator

Job Opportunities for New Biomedical PhDs (starting September 2023)

The Research Operations, Management & Strategy (ROMS) Fellowship is a two-year, paid, full-time position at the U-M Medical School. The fellowship is a type of “alternative” postdoctoral experience, designed to transition biomedical Ph.D. graduates and postdoctoral trainees from the research bench to careers in research operations and administration through a series of unit rotations, hands-on learning experiences, and direct mentorship from leaders in the field.

There will be a virtual information session on Monday, November 14, 2022 from 1:00-2:00pm EST. Here is the link to join the ROMS mailing list to receive the information session link and application timeline information. Any further questions about the fellowship can be directed to ROMS.Fellowship@umich.edu. 

Harvard Initiative for RNA Medicine

Topics in Cancer Genomics

Mark Gerstein, Yale University

Tuesday, October 25, 2022

3:00 - 4:00 p.m.

event details and registration

U-M Department of Chemistry Faculty Candidate Seminar

Using Cryo-EM to visualize dynamic RNA 3D structures and their interactions with proteins

Steve Bonilla, University of Colorado Anschutz Medical Campus

Tuesday, October 25, 2022

4:00 - 5:00 p.m.

Chemistry 1640

U-M Department of Biological Chemistry

Single Particle Cryo-EM of TRPV1: From Atomic Structures to Gating Mechanism

Yifan Cheng, UCSF

Tuesday, November 1, 2022

12:00 - 1:00 p.m.

Medical Science Unit I - 5330 MS I  

U-M Oral Dissertation Defense

Computational Tools for Protein-Protein Interaction Prediction and Analysis

Eric Bell, Advisor: Peter Freddolino

Tuesday, November 1, 2022

3:00 - 4:00 p.m.

Palmer Commons, Forum Hall

U-M Center for Cell Plasticity and Organ Design (COPD)

International Symposium and Poster Session

PDF flyer

Wednesday, November 2, 2022

10:00 a.m. - 6:00 p.m.

event details and registration

RNA Collaborative Seminar host: Harvard Initiative for RNA Medicine

Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.

Below are recent highlights.

Grayeski, P. J., Weidmann, C. A., Kumar, J., Lackey, L., Mustoe, A. M., Busan, S., Laederach, A., & Weeks, K. M. (2022). Global 5'-UTR RNA structure regulates translation of a SERPINA1 mRNA. Nucleic acids research, 50(17), 9689–9704. doi.org/10.1093/nar/gkac739

Magnuson, B., Bedi, K., Narayanan, I. V., Bartkowiak, B., Blinkiewicz, H., Paulsen, M. T., Greenleaf, A., & Ljungman, M. (2022). CDK12 regulates co-transcriptional splicing and RNA turnover in human cells. iScience, 25(9), 105030. doi.org/10.1016/j.isci.2022.105030

Pham, V. V., Gao, M., Meagher, J. L., Smith, J. L., & D'Souza, V. M. (2022). A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA. Communications biology, 5(1), 819. pubmed.ncbi.nlm.nih.gov/35970937

Liu, Y., Munsayac, A., Hall, I., & Keane, S. C. (2022). Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA. Journal of molecular biology, 167688. Advance online publication. doi.org/10.1016/j.jmb.2022.167688