Pediatric multisystem inflammatory syndrome " Why these cases are emerging only now, and what is causing them, is still a mystery. [International PICU COVID19 Collaboration] Panelists speculated that an acquired immune response to COVID activates an inflammatory process in genetically susceptible children. But other mechanisms are possible as well.... If you look at the curves, COVID-19 has plateaued, but there’s an exponential rise in this secondary type of shock syndrome,” says cardiologist  Jane Newburger, MD, MPH , an international expert on Kawasaki disease who was also on the May 2 panel. “It is even possible that the antibodies that children are making to SARS-CoV2 are creating an immune reaction in the body. Nobody knows.”

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