12:40-12:55 – Mingyu Ye, Ph.D.
Transcriptional and functional study of cortical circuit and plasticity in a mouse model of autism
12:55-1:00 – Q&A
Dr. Mingyu Ye is an instructor at the Department of Neurology Mass General Brigham (MGB) and Harvard Medical School (HMS) in Dr. Stelios Smirnakis’ laboratory. He obtained his Ph.D. degree from Tongji University, China in 2011, then worked as a postdoctoral research scientist in Chinese Academy of Science’s Institute of Neuroscience in China (2011-2013), Columbia University (2013-2021), and MGB with a corresponding academic affiliation at HMS (2021-2023). He was promoted to Instructor in 2023. He specializes in sensory neuroscience research. Over the course of his research career, he has learned a number of essential techniques, including mesoscopic two-photon imaging, single cell optogenetics using two-photon laser beam and spatial light modulator (SLM) targeting, patch clamp electrophysiology, multiplex RNA-FISH, AAV mediated brain circuit tracing and manipulation, and mouse behaviors, among others. His research interest and long-term research goal is to decipher how sensory information is encoded in the brain, how cortical sensory processing goes awry at cellular and neural circuit level in neurological disorders, such as autism and Alzheimer’s disease. In addition to research, he is interested in mentoring and providing support to undergraduates, junior pre/postdoctoral fellows and the community at MGB.
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