March 25, 2024

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

CLOSURE

BRAIN

NRG-BN005: Study Closure Memorandum dated March 19, 2024 (posted on CTSU)

AMENDMENT

GYNECOLOGIC

EAY191-N5 (ComboMATCH): Amendment 1 in response to NCI action letter dated March 18, 2024, for CTEP-supported studies that involve palbociclib. Protocol version date: February 15, 2024 (posted on CTSU)

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

2. BIOSPECIMEN BANK

Update! San Francisco Biospecimen Bank (NRGBB-SF) database migration

The date for the NRGBB-SF biospecimen database switchover has been delayed to April 8-19, 2024. Due to this change, NRGBB-SF requests that institutions with the capacity to store their samples collected for biobanking, do so on-site. Do not ship samples to the NRGBB-SF bank between April 8-19, 2024.

• During this time, NRGBB-SF will not provide routine return airbills for frozen shipments without prior authorization and will not be accepting large batch of international/domestic frozen specimens.
• If your site cannot store frozen samples, please contact the bank for prior authorization to ship frozen samples.
• Protocols with mandatory central review or fresh blood processing: These samples can be shipped at any time as usual; database change will not impede patient care or treatment.
• FFPE samples are not affected by this change, sites may ship these as needed. Collection kits may be requested as usual.
• Shipments to the Pittsburgh or Columbus bank are not affected by this change, shipments can be sent as usual.

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

3. BRAIN

NRG-BN010: The Spanish-translated consent forms for Amendment 3 and CIRB approval of the forms are available on CTSU.

4. BREAST

NRG-BR003: Call for submission of data and supporting documentation. Refer to the memo, dated March 25, 2024, posted on CTSU.

NRG-BR007/DEBRA: Study overview webinars are being held via Microsoft Teams on April 19 from 2-3pm ET and April 26 from 12-1pm ET. Please see the memorandum, dated March 25, 2024, (posted on CTSU) for details and how to register for one of the sessions. Please note: Google Chrome is the preferred browser to register for the webinars. 

5. CANCER PREVENTION & CONTROL

NRG-CC010: The study is now open to NRG sites in Japan and South Korea. The optional biospecimen collection does not apply to sites participating in these countries.

6. GENITOURINARY

NRG-GU011:The EPIC Sexual Forms and EPIC Hormonal dictionary errors have been corrected in Medidata RAVE. If these forms were previously submitted, they will now show overdue icons where the data will need to be re-entered. The EPIC-Sexual forms will show two overdue questions and EPIC Hormonal forms will show six overdue items. Please re-enter the data that shows the overdue icons.

7. GYNECOLOGIC

EAY191-N4 (ComboMATCH): Appendix XI, Section II, 1^st bullet: Reports should be REDACTED. Section 10.2: Footnote 2 will be deleted. These changes will be made with the next amendment.

GOG-0210: Reminder: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

NRG-GY031: Please note, there is an error in the section 4.2 table and the Biospecimen Collection and Submission Manual. The Part I PK collection is to be done on Cycle 1, Day 1, and Cycle 1, Day 8. This will be updated with the next amendment.

8. HEAD & NECK

NRG-HN008: Reminder: Please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

9. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, NRG-BR009, NRG-CC011, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, April 10, 2024.

DRUG SAFETY REPORTS

1. Health Disparities Committee Symposium

The NRG Oncology Health Disparities Committee (HDC) will be hosting their annual symposium on Tuesday, April 16, 2024; 3-4:30pm ET. The focus of this year’s symposium will be “Aligning Clinical Trial Development with an Aging Population: Challenges and Opportunities for Older Adults with Cancer.” Refer to the agenda or the flyer for details. Please register in advance for this webinar. After registering, you will receive an email with the webinar link.

2. Annual Call for NRG Oncology Administrative Committee Member Applications

If you are interested in serving on an NRG Oncology administrative committee, or if you are a member who had previously served on a committee and would like to re-engage, please consider applying by April 4, 2024. Click here for instructions and application

3. NRG Oncology is seeking an experienced Patient Advocate to serve as Vice Chair for its Patient Advocate Committee.

Application deadline: April 12, 2024

The Patient Advocate Committee (PAC) is seeking nominations for the position of Vice Chair. This volunteer position provides the selected individual the responsibility of facilitating and guiding the NRG Oncology Patient Advocate Committee (PAC) and program through a process to update its vision and create an action plan to build on its success. Read More

4. Developing and Running an R01 Through NRG NCORP – Register for the webinar to be held on Thursday, April 11, 1-2:30 PM ET

Participants will learn about the NRG NCORP concept review process with a specific focus on R01s.

Dr. Von Ah and Dr. Sikorskii will present their recent experiences R01 concepts through the NRG NCORP, along with lessons learned and benefits of utilizing the NRG NCORP process. A panel of professionals will also be available to discuss their experiences and answer questions from attendees.

The flyer with agenda can be found here.

Register in advance for this meeting. After registering, you will receive an email with the meeting link.

5. NRG Oncology Confidential Member Survey

Please read our survey FAQ’s. All NRG Members should have received an email from the University of Chicago’s Survey Lab containing a unique survey link. If you have not already completed the survey, please check your inbox and possibly your spam/junk mailbox for the email so that you can help us collect this important information. Please send any additional questions to nrg-broadcasts@nrgoncology.org.

6. Early Office Closure

The NRG Oncology Philadelphia East Operations office will close at noon on Friday, March 29, 2024.

NRG Oncology is pleased to report the following scientific articles published during the previous week. Please select “Read More” to access the article online.

PUBLISHED ARTICLES

Buyyounouski MK, Pugh SL, Chen RC, Mann MJ, Kudchadker RJ, Konski AA, Mian OY, Michalski JM, Vigneault E, Valicenti RK, Barkati M, Lawton CAF, Potters L, Monitto DC, Kittel JA, Schroeder TM, Hannan R, Duncan CE, Rodgers JP, Feng F, Sandler HM. Noninferiority of Hypofractionated vs Conventional Postprostatectomy Radiotherapy for Genitourinary and Gastrointestinal Symptoms: The NRG-GU003 Phase 3 Randomized Clinical Trial. JAMA Oncol. 2024 Mar 14:e237291. doi: 10.1001/jamaoncol.2023.7291. Epub ahead of print. PMID: 38483412; PMCID: PMC10941019. Read More

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Association for Cancer Research (AACR); Apr 5-10, 2024; San Diego, CA

American Association for Thoracic Surgery (AATS); Apr 27-30, 2024; Toronto, ON

American Brachytherapy Society (ABS) World Congress; Jul 10-13, 2024; National Harbor, MD

American College of Radiology (ACR); Apr 13-17, 2024; Washington, DC

American Head and Neck Society (AHNS); May 15-16, 2024; Chicago, IL

American Radium Society (ARS); May 2-5, 2024; Palm Springs, CA

American Society of Breast Surgeons (ABS); Apr 10-14, 2024; Orlando, FL

American Society of Clinical Oncology (ASCO); May 31-Jun 4, 2024; Chicago, IL

American Society of Colon and Rectal Surgeons (ASCRS); Jun 1-4, 2024; Baltimore, MD

European Society for Medical Oncology (ESMO) Breast Cancer; May 15-17, 2024; Berlin, Germany

European Society for Radiotherapy and Oncology (ESTRO); May 3-7, 2024; Glasgow, Scotland

Society for Clinical Trials (SCT); May 19-22, 2024; Boston, MA

Western Association of Gynecologic Oncologists (WAGO); Jun 12-15, 2024; Seattle, WA

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Society for Radiation Oncology (ASTRO); Sep 29-Oct 2, 2024; Washington, DC; LBA Jul 12, 2024

EORTC-NCI-AACR Symposium on Molecular Targets and therapies; Oct 23-25, 2024; Barcelona, Spain; due to publications committee Jun 13, 2024; submission deadline Jun 27, 2024; LBA Sep 26, 2024

European Society for Medical Oncology (ESMO); Sep 13-17, 2024; Barcelona, Spain; due to publications committee Apr 23, 2024; submission deadline May 7, 2024, 21:00 CET; LBA Aug 7, 2024, 21:00 CET (placeholder required)

European Society for Medical Oncology (ESMO) Gastrointestinal; Jun 26-29, 2024; Munich, Germany; due to publications committee Mar 26, 2024; submission deadline Apr 9, 2024, 21:00 CET; LBA Jun 6, 2024, 21:00 CET (placeholder required)

European Society for Medical Oncology (ESMO) Gynaecological; Jun 20-22, 2024; Florence, Italy; submission deadline Apr 3, 2024, 21:00 CET

International Society for Quality-of-Life Research (ISOQOL); Oct 13-16, 2024; Cologne, Germany; due to publications committee Mar 25, 2024; submission deadline Apr 8, 2024, CET

International Gynecologic Cancer Society (IGCS); Oct 16-18, 2024; Dublin, Ireland; due to publications committee Apr 16; submission deadline Apr 30, 2024, 23:59 IST; LBA Jul 2, 2024, 23:59 IST

Society for Immunotherapy of Cancer (SITC); Nov 6-10, 2024; Houston, TX; due to publications committee May 15, 2024; submission deadline Jun 27, 2024