The RNA Transcript, January 9th 2023 | |
U-M RNA Innovation Seminar | | |
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Genetic Variant Effects on Adipose Gene Expression and Their Role in Cardiometabolic Traits.
Karen Mohlke, UNC, Chapel Hill
Professor of Genetics & Associate Chair for Research
Oliver Smithies Investigator
TODAY, January 9, 2023
4:00 - 5:00 p.m.
BSRB, ABC Seminar Rooms, Zoom
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Biological Chemistry Innovation Seminar | | |
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Talk Title TBA
Xin Zhang Ph.D., Westlake University
Professor of Chemistry & Cell Biology
Thursday January 12, 2023
4:00 - 5:30 p.m.
Zoom
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Isolation & Molecular Characterization of Single Circulating Tumor & Immune Cells to Examine Heterogeneity
Brittany Rupp, Advisor: S. Nagrath
Thursday January 12, 2023
2:30 pm
NCRC Building 10 Research Auditorium & Zoom (link to follow)
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Biophysics Innovation Seminar | | |
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Talk Title TBA
Rizal Hariadi Ph.D. Arizona State University
Professor of Physics, Mechanisms of Evolution Researchers, Biological Physics, Biodesign Center for Molecular Design & Biomimetics, Biomimetics
Friday January 13, 2023
12:00 - 1:30 p.m.
Zoom (link to follow)
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Speaker: Rachel Niederer
Uncovering Novel Translational Control Elements within 5'-UTRs.
Speaker: Jay Querido
The Structural Basis of Translational Initiation and its Regulation by the RNA Helicase eIF4A
Moderator: Nils Walter
Wednesday, January 18, 2023.
4:00 pm.
Zoom.
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U-M RNA Innovation Seminar | | |
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Talk Title TBA
Carlos Curchaga, Ph.D. Washington University in St. Louis
Director, NeruoGenomics & Informatics Center
January 30, 2023
4:00 - 5:00 p.m.
BSRB, ABC Seminar Rooms, Zoom
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7th Nucleic Acids Conference: 09-12 February 2023 | | |
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In case you are interested in escaping the Michigan winter for a few days and want to help me boost the UM representation at the 7th Nucleic Acids conference. There are some speaker slots still open, and you can bring family and book extra nights.
Registration Closes: January 16th 2023.
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The Research Operations, Management & Strategy (ROMS) Fellowship Application
The ROMS Fellowship is a two-year, paid, full-time position at the U-M Medical School designed to transition biomedical trainees from the bench to careers in research operations and administration through a series of unit rotations, hands-on learning experiences, and direct mentorship from leaders in the field.
The application will be open January 1 – February 19, 2023.
Current fellows will be hosting an informal Q&A-style session on January 19th from 12-1pm EST. You can register for this event HERE.
Any additional questions can be addressed to ROMS.Fellowship@umich.edu
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6th International Course on "Post-transcriptional Gene Regulation: From Mechanisms to RNA Chemistry & Therapeutics" | | |
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The 6th international course on “Post-transcriptional gene regulation: from mechanisms to RNA chemistry and therapeutics" will take place on 24-28 April 2023 at Institut Curie in Orsay (Paris area, France).
We would greatly appreciate if you could transfer this information to your team and colleagues.
For more information, please visit the course webpage: https://training.institut-curie.org/courses/post-transcriptional-gene-regulation-2.
Deadline to register: February 17th
Registration is free but mandatory HERE.
Audience: Master and PhD students coming from European laboratories.
Candidates are selected based on their CV & a letter of motivation (mentioning the research theme and the authorization from the PI).
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The Michigan Institute for Data Science (MIDAS) Fellowship Application | | |
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The Michigan Institute for Data Science (MIDAS) is seeking applications for a new AI in Science Postdoctoral Fellowship Program at the University of Michigan (the Schmidt AI in Science program). Funding for the program comes from the Eric & Wendy Schmidt Postdoctoral Fellowship, a program of Schmidt Futures. This program provides outstanding early-career researchers with intensive training & research experience as they ready themselves for independent research in academic & other sectors. We aim to enable the substantive us of AI for breakthroughs in science & engineering, & cultivate global science leaders. Specifically, we will:
1) Catalyze creative & transformative applications of AI with the potential to lead to major scientific breakthroughs carried out by the Fellows and their mentors.
2) Enable a broader U-M research community to adopt AI in imagining, planning, executing, & supporting research applications across a range of science & engineering domains.
3) Provide outstanding traing to the Fellows.
4) Collaborate with other sites to maximize the impact of the program.
Submit Application: here.
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Postdoctoral & Research Associate Positions in Microbiology & Systems Biology | | |
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The Jiang Lab (www.jianglab.org) at Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York invites applications for Postdoctoral Research Scientist and Research Associate positions in microbiology, microbial engineering and systems biology. We welcome individuals with experimental and/or computational backgrounds to apply. Candidates with specialties in antimicrobial resistance, single-cell RNA-sequencing, CRISPR and various systems biology approaches are highly sought after. To apply, please send your CV and the names and contact details of two or three references to wenyanjianglab@gmail.com
Over the last decade, the PI (Dr. Wenyan Jiang) developed revolutionary technologies that enhance the precision, throughput and resolution for bacterial genomics and transcriptomics. These include development of the very first CRISPR-Cas9 genome editing (Nature Biotech 2013, >2,000 citation) and gene expression modulation technology (Nucleic Acids Research 2013, >1,000 citation) in bacteria; a high-throughput bacterial functional genomics platform called CALM (Cell 2020); and the first bacterial high-throughput single-cell RNA sequencing (scRNA-seq) technology called PETRI-seq (Nature Microbiol 2020). Using these technologies, Jiang lab aims to study microbiology at a systems-level, such as understanding bacterial genetic architecture, evolution, single-cell behaviors, microbe-phage, and host-microbe interactions. The fundamental principles we learn from these studies could help us develop more effective antimicrobial drugs, and engineer commensal bacteria to promote human health.
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Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Nemudraia, A., Nemudryi, A., Buyukyoruk, M., Scherffius, A. M., Zahl, T., Wiegand, T., Pandey, S., Nichols, J. E., Hall, L., McVey, A., Lee, H. H., Wilkinson, R. A., Snyder, L. R., Jones, J. D., Koutmou, K. S., Santiago-Frangos, A., & Wiedenheft, B. (2022). Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic. Research square, rs.3.rs-1466718. https://doi.org/10.21203/rs.3.rs-1466718/v1 https://www.nature.com/articles/s41467-022-35445-5 | |
Watts, J. A., Grunseich, C., Rodriguez, Y., Liu, Y., Li, D., Burdick, J. T., Bruzel, A., Crouch, R. J., Mahley, R. W., Wilson, S. H., & Cheung, V. G. (2022). A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE. Nucleic acids research, 50(21), 12497–12514. https://doi.org/10.1093/nar/gkac1107. doi.org/10.1016/j.jmb.2022.167688 | | | | |
