Never Again
Greetings on Sunday evening. We had a lovely weekend at home, spending time with family, and watched the Eagles run their record to an NFL-best 11-1 with a resounding win over the Tennessee Titans. Perhaps the weekend’s highlight was a performance by the Washington Men’s Camerata, performing at a church in Virginia. The songs were Christmas songs written by Jewish composers or lyricists, including ‘White Christmas’ by Irving Berlin and “The Christmas Song (Chestnuts Roasting on an Open Fire),” written in part by the legendary singer Mel Tormé. One of our neighbors is a member of the Camerata, and we were thrilled to attend.
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Women with Elevated Breast Cancer Risk Could See Mortality Benefit from Estrogen-Blocking Drugs
While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce the risk of developing new breast cancers, a new computer modeling study led by researchers at Georgetown Lombardi and colleagues showed that these treatments could also reduce the risk of dying from the disease in women who are at high risk. Read more about these findings.
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Study in Mice Suggests That Expression of Estrogen-Related Gene Can Impact Post-Menopausal Breast Cancer Risk and Prevention Strategies
In a study using a first-of-its-kind mouse model of aging that mimics breast cancer development in estrogen receptor-positive postmenopausal women, investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues have determined that over-expression, or switching on of the Esr1 gene could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women. Read more about this research.
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Ruesch Symposium Participants Encourage Patients to Consider Clinical Trials
During a panel at the Ruesch symposium called “Facts and Fiction Around Clinical Trials,” Jan Baird-Adams, a librarian from Maryland, spoke about her experience being diagnosed with pancreatic cancer and participating in a clinical trial. This month, Baird-Adams will celebrate one year since being declared cancer-free. Read more about this panel discussion at the symposium.
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Weiner to Participate in Library of Congress Cancer Moonshot Virtual Panel Discussion
Georgetown Lombardi Director Louis Weiner, MD, is one of four panelists invited to participate in this year’s Library of Congress Cancer Moonshot virtual panel discussion, titled “Forecasting Cancer Diagnostics and Treatment for the Future.” The event brings together a White House representative and leading scientists to discuss advancements in cancer prevention, detection, and treatment. Weiner will address the wide choices available for detecting and treating variety of cancers. The panel discussion takes place Tuesday, December 6, 10:30 a.m.-12:00 p.m., via Zoom. Register to attend.
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Tuesday, December 6
9:00 - 10:00 a.m.
Presented by John Psaltis. Mentor: Mary Beth Martin, PhD. Join via Zoom.
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Tuesday, December 6
12:00 - 1:00 p.m.
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Tuesday, December 6
12:00 - 1:00 p.m.
Claire Werner, anatomy PhD candidate, the Pennsylvania State University College of Medicine, will speak about the anatomy, embryology and histology of the breast. Sponsored by the Department of Biochemistry and Molecular & Cellular Biology. Join this seminar in the Pre-Clinical Science Building, GA 2/4 or via Zoom.
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Tuesday, December 6
12:15 - 1:15 p.m.
Presented by John Misasi, MD, associate research physician, chief, Yeast Engineering Technology and Immunobiology Core, Vaccine Research Center, NIAID. Join this seminar in the Medical-Dental Building, NE301 or via Zoom.
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Thursday, December 8
9:00 - 10:00 a.m.
Presented by Youngrok Park. Mentor: Todd Waldman, MD, PhD. Join this presentation in the New Research Building, W302 or via Zoom.
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Thursday, December 8
4:00 - 5:00 p.m.
Presented by Lijie Grace Zhang, PhD, professor and SEAS associate dean for research, Department of Mechanical and Aerospace Engineering, Departments of Electrical and Computer Engineering, Biomedical Engineering, and Medicine
School of Engineering and Applied Science, The George Washington University. Sponsored by the Office of Biomedical Research. Join this seminar in the New Research Building Auditorium or via Zoom.
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Friday, December 9
Seminar: 10:00 - 11:00 a.m.
Meet the Speaker Session: 11:00 - 11:30 a.m.
Presented by Claire Snyder, PhD, MHS, professor of medicine, Division of General Internal Medicine, and oncology, program director, Building Lifestyle, Outcomes, and Care Services Research in Cancer (BLOCS), Johns Hopkins School of Medicine. Join this seminar via Zoom.
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Friday, December 9
12:00 - 1:00 p.m.
Featuring Laura Rozek, PhD, professor of oncology, Cancer Prevention & Control Program, Georgetown Lombardi. Join this lecture in the New Research Building Auditorium or via Zoom.
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Tuesday, December 13
12:00 - 1:00 p.m.
Presented by Ximena Corso Díaz, PhD, MSc, research fellow, Neurobiology, Neurodegeneration and Repair Lab, National Eye Institute, NIH. Sponsored by the Department of Biochemistry and Molecular & Cellular Biology. Join this seminar in the Basic Science Building, Room 341 or via Zoom.
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CDI Seminar: “Leveraging Meditation Mobile Applications in Survivorship Care Among Adolescent and Young Adult Survivors of Childhood Cancer”
Tuesday, December 13
4:00 - 5:00 p.m.
Presented by Gary Kwok, PhD, a postdoctoral fellow in the Pediatric Population Science, Outcomes, and Disparities Research Section within the Division of Pediatric Hematology/Oncology at Rutgers Cancer Institute, New Jersey. Join this seminar via Zoom.
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The Wolpoff Family Foundation made a gift of $15,000 for the Lombardi Arts & Humanities Program, also awarding the program the Harry K. Wolpoff Award of Distinction.
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Funding and Award Opportunities
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The St. Baldrick’s Foundation-American Cancer Society Childhood Cancer Research
The St. Baldrick’s Foundation-American Cancer Society Childhood Cancer Research award provides funding to advance innovative translational pediatric cancer research conducted within the context of a clinical trial. Studies may include analysis of clinical data and biospecimens collected from children enrolled in a clinical trial. Proposals should focus on research leading to improvements in the care of children with cancer. All research proposals must be coupled with ongoing or recently completed, approved pediatric clinical therapeutic trial, such as large/definitive trials conducted in a cooperative group setting. LOI due: Monday, Dec. 5, at 10:59 p.m. EST via proposalCENTRAL. View LOI instructions. Invitations to apply will be issued Wednesday, January 11, 2023.
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NCI Funding Opportunity: Intramural Continuing Umbrella of Research Experiences (iCURE)
The Intramural Continuing Umbrella of Research Experiences (iCURE) program supports mentored research experiences for qualified students and scientists from diverse backgrounds in the multidisciplinary research environment of the NCI campuses in Bethesda, Rockville, and Frederick, Maryland. Individuals from groups that are underrepresented in the biomedical, clinical, behavioral and population sciences are encouraged to apply. The program offers two-year awards for post-baccalaureate (including post-master's) individuals and graduate students and three-year awards for postdoctoral fellows. Application deadline: Dec. 15 for fall 2023 research experiences; target start date will be September 1, 2023. View eligibility information and application instructions.
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AACR Career Development Awards in Lung Cancer Research
The AACR Career Development Awards in Lung Cancer Research encourage and support early career investigators to conduct lung cancer research and establish successful careers in this field. The proposed project may be basic, translational, clinical, or epidemiological in nature and must have direct applicability and relevance to lung cancer. Each award provides $250,000 over two years for expenses related to the research project. NOTE: Applicants must be AACR Active members. Nonmembers can apply for membership online. View program information, including guidelines and eligibility criteria. Application deadline: January 5, 2023, at 1 p.m. ET via ProposalCentral.
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GI Program Funds Award
A newly established Ruesch Center / GI Working Group grant mechanism is currently soliciting research proposals for consideration. Funding will be available to Georgetown Lombardi and MedStar Health scientists and clinicians with a GI cancer-relevant research focus — basic, clinical, population and translational. This set of pilot grants is intended to foster translational collaborations and generate new hypotheses and results to prove them, leading to jointly authored publications. Between two and five one-year collaborative project awards are available, ranging from $25,000 to 50,000 each, with at least two investigators each. View more information and application procedure details. Submit a letter of intent to marshalj@georgetown.edu. LOI Deadline: Friday, January 13, 2023, 5 p.m.
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Breast Cancer Research Foundation Precision Prevention Initiative
The Breast Cancer Research Foundation (BCRF) is requesting applications to its Precision Prevention Initiative. Applications should address the challenges and gaps in primary breast cancer prevention with a focus in one or more of the following categories: risk assessment/stratification, biomarkers, and interventions. Applicants are encouraged to engage collaborators from diverse disciplines and utilize, where possible, areas of expertise and/or methodologies not normally associated with prevention or cancer research. Projects range from single investigator innovation awards to collaborative pre-clinical, translational, clinical and intervention studies. In all cases, projects that impact underserved, minority or high-risk populations are encouraged. Funding levels range from $250,000/year for two years up to $750,000/year for three years. Download the RFA to view program and application details. Letters of intent deadline: January 16, 2023, via ProposalCentral. Invitation to submit full proposals issued by March 3, 2023.
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Meetings in italics should be attended by all fellows.
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9:00 AM | Breast Research Meeting | Podium A / Zoom (dial 646-558-8656; Meeting ID: 528212194)
11:00 AM | GU/Melanoma Research Meeting | Podium A / Zoom (dial 646-558-8656; Meeting ID: 796253566)
12:15 PM | Systemic Therapy for Metastatic HR+/HER2- Breast Cancer – Dr. Ashai | Podium A / Zoom
4:00 PM | GU Tumor Board (on 1st/3rd Mondays of the month) | Podium A / Zoom (dial 646-558-8656; Meeting ID: 869742463)
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9:00 AM | PhD Thesis Defense: Speaker: John Psaltis | “The Role of Cadmium in the Activation of the Estrogen Receptor Alpha and Endocrine Resistance” | Zoom
9:00 AM | Hematology Path Conference - Inpatient Heme fellows + Outpatient Heme + BMT fellow | Podium A / Microsoft Teams (CME code: 80737; phone: 202-796-7323)
12:15 PM | Protocol Writing Series #4 with Dr. Hongkun Wang and Dr. Weinberg | Podium A / Zoom
4:00 PM | Liver Tumor Board | WebEx (dial 844-302-0362; Meeting number (access code): 711 507 430, password: Mse4mGSA2N5)
5:00 PM | Breast Tumor Board | Podium A / Zoom (dial 646-558-8656; Meeting ID: 93777073374; CME code: 80044)
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8:00 AM | Thoracic Tumor Board – Thoracic Fellow | Podium A / Zoom (dial 646-558-8656; Meeting ID: 941 1630 5835)
12:15 PM | Non-Sickle Hemoglobinopathies - Dr. Smith | Podium A / Microsoft Teams
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9:00 AM | PhD Thesis Defense: Speaker: Youngrok Park | “The Role of STAG2 in Bladder Cancer: Clinical Implications as a Biomarker and Potential Mechanisms of Tumorigenesis” | W302 New Research Building or Zoom
9:30 AM | Head and Neck Tumor Board - Thoracic Fellow attendance encouraged as clinic allows | Microsoft Teams
12:15 PM | Journal Club – Drs. Diltz and Dunleavy | Podium A / Zoom
12:30 PM | GI Research Meeting | WebEx (dial 844-302-0362, Meeting Number (access code): 712527865, HOST PIN: 5514)
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7:00 AM | CNS Tumor Board | Zoom (dial 646-558-8656; Meeting ID: 378 807 316)
12:00 PM | Oncology Grand Rounds Lecture Series: Laura Rozek, PhD | “Molecular Epidemiology and Head and Neck Cancer: Integrating Data from a Large Clinical Cohort” | New Research Building Auditorium or Zoom
12:00 PM | No Lecture | Zoom
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Connect with Georgetown Lombardi on Social Media
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If you would like to share news or updates from your department, please get in touch with Sarah Riehl.
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