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What a thrill it was to welcome our keynote speakers, including the 2023 Nobel Prize laureate for Physiology and Medicine Dr. Drew Weissman, and registrants to the U-M Ann Arbor campus on Friday, March 8, as well as those who joined us LIVE via Zoom.
MiSciWriters correspondents were once again on hand to LIVE Tweet throughout the event and capture all the stories. Be sure to check out their Blog posts written live during the 8th annual RNA Symposium, “Unmasking the Power of RNA: From Structure to Medicine." Follow MiSciWriters’ coverage of this event on Twitter with the hashtag #umichrna.
Thanks to all our speakers, attendees, sponsors, friends, colleagues, and MiSciWriters. Stay tuned for further updates and some exciting announcements!
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Today: RNA Innovation Seminar Series | Monday, March 18, 4:00-5:00 p.m. | | |
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RNA Innovation Seminar Series
"Transcription-driven DNA repair"
Julie Wilson Anderson Professor of Biochemistry
Department of Biochemistry & Molecular Pharmacology
New York University
T'oday - Monday - March 18, 4:00 p.m. - 5:00 p.m. ET
BSRB ABC Seminar Rooms, Hybrid Link
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HMS Initiative for RNA Medicine Seminar Series | | |
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Christine M. Eischen, PhD
Herbert A. Rosenthal, MD ’56 Professor of Cancer Research
Co-Leader, Immune Cell Regulation and Targeting Program, Sidney Kimmel Cancer Center
Co-Director, Blood Cancer Center of Excellence
Thomas Jefferson University
Non-coding RNA that regulate tumorigenesis
Tuesday, March 19, 2024 | 3:00 – 4:00 PM EST
Virtual Seminar
To Join Click this link: https://qrco.de/besJgj
For questions reach out to Grace Lee at glee8@bidmc.harvard.edu
You can view all recorded seminars on the HIRM video gallery
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“A stem cell approach to human genetics- from CRISPR screens in hPSCs to genes, enhancers and disease.”
Presented by:
Danwei Huangfu, Ph.D.
Professor and Member
Developmental Biology Program
Sloan Kettering Institute
Memorial Sloan Kettering Cancer Center
Monday, March 25, 2024
11:00 AM – 12:00 PM EST
Kahn Auditorium, BSRB
Hosted by: Sundeep Kalantry, Ph.D.
Professor of Human Genetics
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RNA Collaborative Seminar Series | |
From our sponsor: Lexogen RNA Expertise Blog Series | | |
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Single-cell RNA-Seq has revolutionized the field of transcriptomics, providing unprecedented insight into cellular complexity and heterogeneity. In our first blog post of the RNAEXPERTise Blog Series on Single-Cell RNA-Seq – “Classical Single-Cell RNA Sequencing: a comprehensive overview” – we talked about the basic principles, benefits, and most common applications of classical single-cell RNA-Seq.
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Kathleen Collins publishes findings from a recent study on HIV protein that could help pave way for cure | | |
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University of Michigan Center for RNA Biomedicine faculty member Kathleen Collins, M.D., Ph.D., and colleagues publish findings from recent study, helping to open a promising pathway for the development of a cure for HIV rather than just a treatment.
"Structure–Activity Relationships of Natural and Semisynthetic Plecomacrolides Suggest Distinct Pathways for HIV-1 Immune Evasion and Vacuolar ATPase-Dependent Lysosomal Acidification"
Journal of Medicinal Chemistry, March 7, 2024,
DOI: 10.1021/acs.jmedchem.3c01574
Read the full article in The University Record.
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Pedro Lowenstein develops new model of known brain tumor feature | | |
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Center for RNA Biomedicine faculty member Pedro Lowenstein, M.D., Ph.D., led a team in a recent study of onostreams, a key feature for glioblastoma development, and identified a potential inhibitor that appears to dismantle these aggressors.
"Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways"
Published in Advanced Science, 22 February 2024 https://doi.org/10.1002/advs.202309796
Read the full story in Michigan Medicine's Health Lab
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In Case You Missed It ... | |
Stephen Parker, Ph.D, establishes new Epigenomic Metabolic Medicine Center (EM2C) | | |
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Congratulations to Dr. Stephen Parker, Associate Professor of Computational Medicine and Bioinformatics, Human Genetics, and Biostatistics on the formation of the Epigenomic Metabolic Medicine Center (EM2C) at the U-M Medical School. The new Center aims to perform population-scale single-cell multi-omics profiling with the goal of better understanding how genetic variations contribute to common, complex diseases, such as diabetes and related traits. Once new genetic mechanisms are identified, researchers can use this information to develop better strategies to detect, treat, and prevent these diseases.
READ about EM2C
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Maria Castro and Pedro Lowenstein project selected for STAT Madness Tournament of Science | | |
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BioInnovations in Brain Cancer Program
Fellow Biosciences Initiative center, BioInnovations in Brain Cancer, announced on March 4 that the BIBC project, a phase 1 first in human Clinical trial, led by Dr. Pedro Lowenstein and Dr. Maria G. Castro, has been selected as one of the four UofM entries for the STAT Madness tournament of science.
Maria Castro, Ph.D., and Pedro Lowenstein, M.D., Ph.D., are Faculty Members of the Center for RNA Biomedicine.
Please take a few minutes to vote for the BIBC project by clicking on the U-M Rogel Cancer Center project.
Congratulations Maria and Pedro!
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"Structure and Targeting of Precursor MicroRNA-31: From Mechanism to Application"
Sicong Ma, Biophysics
Advisor: Sarah Keane
Wednesday, March 27, 2024
1:00 PM
EARL LEWIS ROOM (RACKHAM) & ZOOM
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For more information and to view the full schedule of upcoming U-M Oral Defenses, please visit the Rackham Graduate School Oral Defenses website. | |
This Week - National Academies Webinar - Thursday, March 21 | |
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Charting a Future for Sequencing RNA and Its Modifications: Report Release Webinar - Thursday, March 21, 2:00 p.m. - 3:00 p.m. ET.
RNA modifications are pivotal players in diverse biological processes and have implications in various human diseases and disorders. However, our understanding of these crucial molecular features remains incomplete, hindered by current technological limitations. Existing methods cannot currently discover all RNA modifications, let alone comprehensively sequence them on every RNA molecule. This shortfall poses a significant obstacle in harnessing the full potential of RNA modifications to address pressing societal challenges in health, agriculture, and beyond. Please join the National Academies for a webinar on Thursday, March 21, 2024, from 2-3 pm EST, as we unveil our new report. This report charts a forward-looking trajectory for sequencing RNA and its modifications, laying the foundation for a new era in biology and medicine. During the webinar, members of the study committee will present key insights and recommendations, inviting audience engagement through an interactive Q&A session.
Register here: https://events.nationalacademies.org/42184_03-2024_toward-sequencing-and-mapping-of-rna-modifications-report-release-webinar
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HIRM 2024 Symposium, April 25, 2024 - Registration Open! | | |
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2024 Symposium
HIRM 10 Year Anniversary Symposium
Thursday, April 25, 2024
Joseph B. Martin Conference Center
77 Avenue Louis Pasteur
Boston, MA 02115
Registration Open
Poster Submissions now closed.
For more information, contact Grace Lee at glee8@bidmc.harvard.edu
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RNA Society Annual Meeting May 28 - June 2, 2024 | |
6th Annual RNATx Umass June 26-28, 2024 | | |
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2024 RNATx Registration
From Concept to Clinic happening both in person and virtually, at the RNA Therapeutics Institute at UMass Chan Medical School
June 26 - June 28, 2024
We invite you to share your work with leading RNA Investigators by submitting your abstracts. We will be evaluating abstracts for a limited number of short talks, so submit yours early!
Oral Abstract submissions now closed.
Poster Abstract submission deadline: March 22, 2024
Early Registration Deadline: April 19, 2024
See abstract guidelines and tips for proper formatting and how to write your abstract.
Please see our symposium website for details and do not hesitate to contact us if you have any questions at RNATherapeutics@umassmed.edu.
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Gordon Conference on Post-transcriptional Gene Regulation July 14-19 | | |
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Check out the scientific program lined up for the July 14-19 Gordon Conference on Post-transcriptional Gene Regulation in beautiful Portland, ME! This year’s theme is The Versatility of RNA in the Living World. Attendance is limited, so we are trying to get the word out that interested folks should apply before March 15th for the best chance of availability. Trainees: see the associated Gordon Research Symposium as well!
For more information and registration, visit https://www.grc.org/post-transcriptional-gene-regulation-conference/2024/
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RiboClub 25th / RiboWest 20th / TREnD 8th Anniversary Celebration in Ottawa: RNA Canada 2024: The future of RNA technology | |
NEW! Non-coding RNA World 2024: Exploring Mechanisms, Designing Medicines | October 7-9, 2024 | | |
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Join us in Basel in October to learn about the latest developments in Non-Coding RNA research. Mingle with the world-leading invited speakers during ample networking opportunities. Present your research at poster sessions and numerous selected oral presentations. Discover the beautiful mediaeval city of Basel.
More details and abstract submission here: https://sciforum.net/event/ncRNA2024
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Our members' publications are available through Altmetric. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.
Below are recent highlights.
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Tseng YJ, Krans A, Malik I, Deng X, Yildirim E, Ovunc S, Tank EMH, Jansen-West K, Kaufhold R, Gomez NB, Sher R, Petrucelli L, Barmada SJ, Todd PK. Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats. Nucleic Acids Res. 2024 Feb 27:gkae137. doi: 10.1093/nar/gkae137. Epub ahead of print. PMID: 38412259. | |
Wells AE, Wilson JJ, Heuer SE, Sears JD, Wei J, Pandey R, Costa MW, Kaczorowski CC, Roopenian DC, Chang CH, Carter GW. Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice. PLoS One. 2024 Mar 7;19(3):e0299595. doi: 10.1371/journal.pone.0299595. PMID: 38451972; PMCID: PMC10919611. | |
Taylor AS, Mannan R, Pantanowitz L, Chinnaiyan AM, Dhanasekaran SM, Hrycaj S, Cao X, Chan MP, Lucas D, Wang XM, Mehra R. Evaluation of TRIM63 RNA in situ hybridization (RNA-ISH) as a potential biomarker for alveolar soft-part sarcoma (ASPS). Med Oncol. 2024 Feb 23;41(3):76. doi: 10.1007/s12032-024-02305-9. PMID: 38393424; PMCID: PMC10891236. | |
Emery T. Usher, Rishav Mitra, James C. Bardwell, Alex S. Holehouse, Computational study of RNA binding by a short intrinsically disordered protein, Biophysical Journal, VOLUME 123, ISSUE 3, SUPPLEMENT 1, 216A, FEBRUARY 08, 2024, DOI:https://doi.org/10.1016/j.bpj.2023.11.1370 | |
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The Department of Molecular Genetics in the College of Arts and Sciences at The Ohio State University invites applications for the position of Ohio Eminent Scholar in Molecular Genetics, an endowed, tenure-track position at the Associate or Full Professor level. The Ohio Eminent Scholars (OES) Program, created by the Ohio General Assembly and administered by the Ohio Board of Regents, aims to enhance the national eminence of selected outstanding academic programs at Ohio universities by attracting internationally recognized scholars. Applications are sought from those with a distinguished track record of investigating fundamental biological questions in any system.
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University of Michigan BIBC Tenure Track Faculty Search - Deadline: Mar 31, 2024 at 11:59 PM EDT
The University of Michigan has launched a Tenure Track Faculty Search for the BioInnovations in Brain Cancer Initiative (BIBC), led by Center for RNA Biomedicine Faculty Member Dr. Maria G. Castro and Dr. Steven Schwendeman. Learn more.
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The University of California Irvine (UCI), Department of Ophthalmology Full-Time Position
Inviting applicants focused on the development of genetic engineering and genome editing technologies. Learn more.
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Postdoctoral Research Fellow and Graduate Research Assistants
Dr. Guizhi (Julian) Zhu Lab | University of Michigan
Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.
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For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website | | | | |
