The CCTS Investigator
Accelerating Discoveries Toward Better Health
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What's New in Translational Science? |
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Researchers at the Icahn School of Medicine at Mount Sinai in New York [external link] and NCATS [external link] identified compounds that, when tested in patient cells and mice, reversed the effects of several neurodegenerative diseases called lysosomal storage disorders (LSDs). The findings could lead to treatments for other neurodegenerative diseases that have similar causes.
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The Ohio State University Center for Clinical and Translational Science is planning our Annual Scientific Meeting [external link] for January 2023.
We encourage you to share your thoughts in planning for our next meeting. We strive to meet the needs of our Center for Clinical and Translational Science (CCTS) members and value your feedback.
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We are excited to share that the University of Rochester (UR) is hosting the I-Corps@NCATS Regional Short Course this fall, specifically designed for biomedical scientists, clinician scientists and engineers, to provide a new approach to accelerate translation of discoveries from the lab to clinical practice. This program, supported by the NIH National Center for Advancing Translational Sciences (NCATS), is based on the National Science Foundation's Innovation Corps (I-Corps™) program, the premier federally funded innovation and commercialization training in the U.S.
The program will kick off the week of October 17 and run for five weeks. All sessions will be held virtually over zoom.
The I-Corps@NCATS Regional Short Course is free for participants, including teams of faculty, postdocs and students with biomedical innovations or ideas. Course graduates receive National Science Foundation (NSF) lineage and can apply to other NSF grant awards, including the National I-Corps Team program, which carries a grant award of up to $50,000. Previous NSF funding is not required to apply.
This program is being hosted by the Ain Center for Entrepreneurship and Innovation and the UR Clinical and Translational Science Institute.
Logo courtesy of I-Corps@NCATS
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The Center for Clinical and Translational Science along with their Recruitment and Retention program is excited to announce that a newly redesigned StudySearch website will be unveiled soon. Watch for new features, updates and a whole new look to our site.
Principal Investigators, do you have an IRB approved study that is seeking volunteers? StudySearch is an online, plain language listing of Ohio State and Nationwide Children's Hospital studies that are seeking volunteers. No additional IRB oversight is necessary to list your study. This site regularly receives 2,000-5,000 visitors per month.
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The 2022 Appalachian Translational Research Network (ATRN) Health Summit is now accepting abstracts for oral, poster and symposium presentations.
This year's theme is Community-Academic Engagement: Building Resilience Together.
The University of Kentucky will host the in-person, 12th Annual Summit on November 14 - 15, 2022 at the Gatton Student Center, University of Kentucky campus.
Logo courtesy of ATRN
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Path to K Mentored Career Development Grant
Request for Applications
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The Ohio State University Center for Clinical and Translational Science (CCTS), the Office of Health Sciences (OHS) and the College of Medicine are seeking applicants for an innovative career development program to train and help prepare clinical and/or translational investigators for a successful K grant application.
The Path to K Program supports career development of investigators from all Ohio State health science colleges who have made a commitment to conduct either patient-oriented or translational research. The Path to K Grant is available for a period of up to two years (contingent on satisfactory progress).
Letter of Intent Due: October 16, 2022
Full Application Due: December 18, 2022
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CCTS Mentored Career Development Grant Update |
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The CCTS KL2 Mentored Career Development Grant will soon become the CCTS K12 Mentored Career Development Grant. CCTS is in the process of applying to the NIH for the renewal of this grant. When funded, it will be called a K12, but will still provide the excellent training opportunity for junior faculty on their journey to becoming independent, R01 funded clinical and translational researchers.
Because of the transition, the RFA will not be released at this time as it has been previously. It is anticipated that the RFA will be released spring 2023. The anticipated start date for funded scholars is July - August 2023.
The CCTS KL2 Program supports the career development of investigators who have made a commitment to conduct either patient-oriented or translational research. The award is designed to benefit a wide spectrum of clinical or translational researchers across Ohio State. The award provides salary support to ensure protected time for mentored research and didactic training in clinical/translational research across a wide variety of project topics and academic areas. The overall goal of the program is to equip early-career investigators to advance from mentored to independent researchers funded by NIH RO1 grants or their equivalents.
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CCTS Mentored Clinical Research Training Grant Update |
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CCTS TL1 Mentored Clinical Research Training Grant will soon become CCTS T32 Mentored Clinical Research Training Grant. CCTS is in the process of applying to the NIH for renewal of this grant. When funded, it will be called a T32, but will still provide the excellent training opportunity for pre-doctoral students on their journey to becoming clinical and translational researchers.
Because of this transition, the RFA will not be released at this time as it has been previously. It is anticipated that the RFA will be released spring 2023 and will only be available for pre-docs. The anticipated start date for funded scholars is July - August 2023.
The goal of the TL1 Mentored Clinical Research Training Program is to increase the number of well-trained clinician-scientists who can lead the design and oversight of future clinical investigations critical to address the nation's biomedical, behavioral and clinical needs.
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The CCTS Voucher Award Program is renewed for the 2022 - 2023 Grant Year.
Voucher Applications will be accepted on a rolling basis beginning June 1, 2022. The current grant year ends May 31, 2023.
CCTS will award Ohio State and Nationwide Children's Hospital investigators vouchers worth up to $3,000 in core services per investigator and per project.
To support new collaborations, CCTS will award The Ohio State University and Nationwide Children's Hospital investigators up to $5,000 for projects involving researchers from two different colleges or institutions. The purpose of this voucher is to support interdisciplinary research and collaboration across colleges and between Ohio State and Nationwide Children's Hospital.
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CCTS Funding Opportunities and Events |
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Social media isn't just for personal usage anymore. Learning the tips and tricks to use social media to your advantage when promoting research will provide you with another avenue to advance your research career. This session will provide attendees with information related to the most effective ways to use social media to increase your professional visibility and engage with colleagues across the world.
When: October 11, 2022, 11 a.m. - 12:30 p.m. EST
Where: Online
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Speakers:
Dr. James MacDonald [external link]: Assistant Professor, Department of Pediatrics and Family Medicine & Physician for Nationwide Children's Sports Medicine
Dr. Tamar Gur [external link: Assistant Professor of Psychiatry, Neuroscience and Obstetrics & Gynecology
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Photo courtesy of Nationwide Children's Hospital |
Photo courtesy of Ohio State Wexner Medical Center |
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The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC) proudly presents Shared Insights, a hybrid seminar series exploring biomedical research at Ohio State. Join us to hear from OSUCCC core directors as they share how their core contributes to vital cancer research utilizing state-of-the-art equipment and cutting edge science and expertise.
In addition, cancer-focused super users will present on the research that has been directly influenced by the featured core.
First Segment
When: October 11, 2022, 2 - 3 p.m. EST
Where: The James Cancer Hospital, Room B050
What: Clinical Translational Science Shared Resource and their new Aging Biomarkers branch.
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Are you a faculty member looking for your next collaborator on campus? Are you trying to find an exciting new angle for your research? Could you make a unique contribution to an interdisciplinary team but don't know where to start?
The Office of Knowledge Enterprise's BIIG Collaborations is a series of activities designed to provide faculty with the resources and support needed to establish and cultivate collaborations across disciplines, and explore innovative research questions. The program kicks off with two events to begin to forge collaborative interdisciplinary teams seeking to innovate around a common research theme.
Teams can also apply for an Interdisciplinary Innovation Team Development Award that provides up to $5,000 to further define and refine budding interdisciplinary collaborations that are poised to tackle complex problems.
When: October 11 - 12, 2022, 3 - 5 p.m. EST
Where: STEAM Factory, 400 W. Rich St. Columbus, OH 43215
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Hallie Barr, PharmD, BCOP, will be presenting at the October 13, CRPTS session. This presentation will focus on appropriate control, storage and dispensation of investigational products according to applicable regulations, policies and guidance at the federal and local level. A review of common deviations will be presented, as well as an introduction to the role of an investigational drug service (IDS).
When: October 13, 2022, 9 - 10 a.m. EST
Where: Online
Photo courtesy of Ohio State Pharmacy Residency Program
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CCTS, and partner Fisher College of Business Executive Education, present The Business of Science, a workshop designed to provide faculty researchers in the health and biomedical sciences with enhanced skills in innovation, project management and team leadership. The sessions are practically oriented, interactive and introduce participants to methods they can implement immediately in their research projects.
One participant commented, "This course has challenged me to think in new ways and be innovative while making good decisions."
Faculty from all ranks are encouraged to apply by September 5.
When: October 26, 2022, 8 a.m. - 5 p.m. EST
October 27, 2022, 8 a.m. - 5 p.m EST
October 28, 2022, 8 a.m. - 5 p.m EST
Where: Mason Hall, Fisher College of Business Campus
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The two-session workshop uses a case-based, discussion-oriented curriculum designed by the Center for the Improvement of Mentored Experience in Research (CIMER) that is theoretically grounded, evidence-based, and culturally-responsive. The training is designed to help faculty who mentor early career researchers, whether junior faculty, postdoctoral trainees or graduate students, to become more effective research and career mentors.
This is the first of three iterations to be offered virtually during the 2022-2023 Academic Year. The second will be February 28 - March 1, 2023 and the third in early to mid-May 2023, exact dates to be developed.
When: October 26 - 27, 2022, 1 - 3 p.m
Where: Zoom
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The work of CCTS wouldn't be possible without our knowledgeable program managers and administrative staff. View our full team here. [external link]
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This month, meet Holly Borghese, DVM!
Q: What is your role at CCTS?
A: I oversee the Veterinary Biospecimen Repository, a component of the Comparative and Translational Medicine Program of the CCTS.
Q: How do you think CCTS is impacting medicine?
A: It is coordinating a vast number of resources to speed the benchtop to bedside pipeline to new diagnostics and therapies. In my area, as researchers continue to learn the value of spontaneous disease models in pets, there is more collaboration between veterinary and human medicine. We know this can save time and money in the pre-clinical phase of development.
Q: What's your typical day like?
A: My days can vary quite a bit. Some days I am racking up 15,000 steps, running up down the stairs collecting tumors from surgery and processing the samples in my lab. Other days can be spent at my desk do data entry or searches, emails, meetings and working out details on requested materials. Some days seem like they are all problem solving.
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700 Children's® – A Blog by Pediatric Experts
Nationwide Children's Hospital
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Defiant behavior among toddlers and young children is a normal phase of child development. Children might throw temper tantrums or have rapid mood changes.
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External Funding Opportunities and Events |
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Recruitment made easier!
ResearchMatch [external link] is Ohio State's disease-neutral online volunteer registry and recruitment tool. Since 2010, ResearchMatch has been an effective recruitment tool that connects research teams with people who are interested in learning about research studies. ResearchMatch volunteers want to be contacted by researchers who are recruiting volunteers to take part in their research studies. ResearchMatch is funded in part by the National Center for the Advancing Translational Sciences (NCATS) [external link], an office of the National Institutes of Health (NIH).
Researchers, if you are interested in learning how you can use ResearchMatch to recruit participants for your study, email Mary Becker [email] or Clara Kalis [email] at CCTS to learn more.
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REDCap Office Hours via Zoom
When: Every Monday, 11 a.m. - 1 p.m. EST
Every Wednesday, 1 p.m. - 3 p.m. EST
REDCap Training Resuming
The Ohio State Center for Clinical and Translational Science, in coordination with the Department of Research Information Technology (RIT), conducts monthly training sessions via Microsoft Teams.
There are four modules of training based on the role(s) a user will have within REDCap. Registration for each session opens two weeks prior to the session.
This level of training is appropriate for projects that have questions about collecting Electronic Informed Consent. We will be discussing the current eSignature rules and regulations, the new workflow for requesting the eConsent Extension (fee for service) and the implementation of eConsent Extension DIY.
Great for people who cannot attend the Grand Rounds session.
When: Last Wednesday of each month, noon - 1 p.m. EST
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This month's topic is REDCap Creative Uses 2.0
The monthly topics will be posted on the REDCap blog [external link]. Advance registration is requested.
When: Second Tuesday of each month, 11 a.m. - noon
Where: Zoom
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Read about the latest translational science news, opportunities and announcements in the latest edition of the NCATS e-Newsletter and the NIH's Weekly Funding Notice.
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Learn more about PCORI through their blog, video room, news releases and other resources.
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Visit our website [external link] or click on the social media icons below to be directed to our social pages (Facebook, Twitter, Youtube).
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Publications supported by CCTS are required to cite The Ohio State University Center for Clinical and Translational Science.
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