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The RNA Transcript, October 10, 2022

Two Special Events Today

--4:00 p.m. Polly Hsu, Michigan State University

--BSRB, ABC room with zoom option

--event details

--6:00 p.m. Panel Discussion on Science and Ethics

--7:00 p.m. Screening of GATTACA

--Michigan Theatre (603 E Liberty St, $10.50 adults, $8.50 students)

--event details

U-M Oral Dissertation Defense

The Role of SWI/SNF Chromatin Remodeling Complex Subunit SMARCD1 in Vascular Diseases

Yang Zhao, advisors: Yuqing Chen and Jifeng Zhang


Monday, October 10, 2022

9:00 - 10:00 a.m.

THSL 2903

U-M Oral Dissertation Defense

Statistical Methods for Gene Differential Expression Detection and Cell Trajectory Reconstruction From Single-Cell Rna Sequencing Data

Jingyi Zhai, advisor: Hui Jiang


Tuesday, October 11, 2022

10:00 - 11:00 a.m.

SPH II M4117

U-M Biological Chemistry Seminar

Single-Molecule Cell Biology Reveals the Molecular Mechanisms of Genome Integrity Pathways in Cancer Cells-Department of Biological Chemistry Seminar Series

Jens Schmidt, Michigan State University


Tuesday, October 11, 2022

12:00 - 1:00 p.m.

5330 Med Sci I

Dana-Farber Cancer Institute, Pediatric Oncology

Transcriptional circuits drive isotretinoin-induced differentiation and genetic predisposition in neuroblastoma

A. Thomas Look, Harvard Medical School


Wednesday, October 12, 2022

8:15 - 9:15 a.m.

Zoom

U-M Oral Dissertation Defense

Epigenetic Reprogramming in Mutant IDH1 Glioma Influences Radioresistance and Neural Lineage Differentiation

Stephen Carney, advisor: Maria Castro


Wednesday, October 12, 2022

9:00 - 10:00 a.m.

Zoom, passcode: nature

U-M Oral Dissertation Defense


Sara Tweedy, advisor: Charles Brooks


Wednesday, October 12, 2022

10:00 - 11:00 a.m.

Zoom

UMass Chan Medical School, Science Café

A S(p)lice of the piRNA: What Small RNAs Can Teach Us

Milky Abajorga (Luban and Theurkauf labs) and Dr. Maya Spichal (Mello lab), will discuss how piRNAs are made in cells and their role in fertility using various model organisms such as the mouse, worms, and koalas! 


Wednesday, October 12, 2022

6:30 - 7:30 p.m.

RSVP link

U-M Microbiology and Immunology Seminar

mRNA 3’ processing in development and virus-host interactions

Yongsheng Shi, UC Irvine

Faculty Host: Katherine R. Spindler / Flyer in PDF


Thursday, October 13, 2022

12:00 - 1:00 p.m.

M3330 Med Sci I

RNA Society of North Carolina Symposium
The symposium will feature world-class speakers, talks from submitted abstracts, and many great opportunities for networking. Abstract deadlines are Sept 16th (to be considered for talks) and Sept 26th for posters.

October 13–14, 2022
Durham, NC

U-M Structure Seminar

The "structural" journey of a ribonucleoprotein complex: From molecules to droplets

Rishav Mitra, James Bardwell Lab


Friday, October 14, 2022

10:00 - 11:00 a.m.

LSI Library

U-M Human Genetics Seminar

Genomic Medicine for Rare and Common Diseases

Gail Jarvik, University of Washington


Friday, October 14, 2022

12:00 - 1:00 p.m.

BSRB, Kahn Auditorium

Rustbelt RNA Meeting 2022
The Rustbelt is in-person and excited to offer Presentations, Workshops, Awards, and more!

October 14–15, 2022
Cleveland OH

U-M Center for RNA Biomedicine

The Democratization of RNA Therapeutics

John Cooke, Medical Director, Center for RNA Therapeutics

Houston Methodist 


Monday, October 17, 2022

4:00 - 5:00 p.m.

BSRB, ABC room zoom option

Harvard Initiative for RNA Medicine

Enhancing miRNA therapeutics through vehicle-free delivery and full chemical modification

Andrea Kasinski, Purdue University  


Tuesday, October 18, 2022

3:00 - 4:00 p.m.

Zoom

RNA Collaborative Seminar

host: Helmholtz Institute for RNA-based Infection Research (HIRI)

Wednesday, October 19, 2022

10:00 - 11:00 a.m.

Zoom link

Probing the structure and function of viral RNAs

Redmond Smyth


Regulation of miRNA processing by other miRNAs through sequence specific RNA:RNA interactions

Bhupesh Prusty


Moderator: Neva Caliskan

Job Opportunities

Assistant Professor of Physical Chemistry Kalamazoo College


The Department of Chemistry and Biochemistry at Kalamazoo College invites applications for a tenure-track Assistant Professor of Physical Chemistry. The position will begin September 2023. A Ph.D. in Physical Chemistry, or the equivalent, is required. Primary responsibilities include teaching classes in physical chemistry, general chemistry, and the Shared Passages program, as well as participating in departmental review of senior individualized projects and developing an active research program. Candidates are expected to have high aptitude and interest in undergraduate teaching, a commitment to the liberal arts, and a desire to involve undergraduate students in scholarship both inside and outside of the classroom.


Kalamazoo College is a nationally known liberal arts college offering an integrated undergraduate experience that weaves a traditional liberal arts curriculum into domestic and international educational experiences. It is a member of the Posse Program and home of the Arcus Center for Social Justice Leadership. Approximately 10% of its students major in Chemistry or Biochemistry. The campus is located in a diverse and vibrant city in southwestern Michigan, midway between Chicago and Detroit. Kalamazoo is the home of the Kalamazoo Promise.


Review of completed applications will begin October 17, 2022, and will continue until the position is filled. 


Link to application

Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights.

Magnuson, B., Bedi, K., Narayanan, I. V., Bartkowiak, B., Blinkiewicz, H., Paulsen, M. T., Greenleaf, A., & Ljungman, M. (2022). CDK12 regulates co-transcriptional splicing and RNA turnover in human cells. iScience, 25(9), 105030. doi.org/10.1016/j.isci.2022.105030

McLean, E. K., Nye, T. M., Lowder, F. C., & Simmons, L. A. (2022). The Impact of RNA-DNA Hybrids on Genome Integrity in Bacteria. Annual review of microbiology, 76, 461–480. doi.org/10.1146/annurev-micro-102521-014450

Pham, V. V., Gao, M., Meagher, J. L., Smith, J. L., & D'Souza, V. M. (2022). A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA. Communications biology, 5(1), 819. pubmed.ncbi.nlm.nih.gov/35970937

Liu, Y., Munsayac, A., Hall, I., & Keane, S. C. (2022). Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA. Journal of molecular biology, 167688. Advance online publication. doi.org/10.1016/j.jmb.2022.167688

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