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Volume 10 - March 2023
Shape the Future of Treatments in Esophageal Diseases

The ISDE 2023 Congress team cordially invites you to submit your abstracts for the 19th ISDE World Congress for Esophageal Diseases. Don't miss the opportunity to showcase your latest findings and make an impact in front of a global audience of peers and experts!

Be part of the multidisciplinary program and shape the future of treatments in Esophageal Diseases by sending in your abstracts today!
Looking Forward to ISDE 2023 in Toronto!

We are pleased to announce that ISDE 2023 will be held at the Sheraton Centre Toronto Hotel which is centrally located in the financial district of the city, close to the Eaton Centre, The Hockey Hall of Fame, CN Tower, and many popular museums and dining venues.


Looking forward to seeing you at ISDE 2023! Stay tuned for more information to come.
Support the Future of Treatments in Esophageal Diseases

We invite you to participate in the progress towards advancing new treatments for esophageal diseases by supporting the 19th ISDE World Congress!

ISDE 2023 offers an excellent opportunity to network with an international group of gastroenterologists, oncologists, radiologists, surgeons, and more to build relationships and elevate your brand's exposure to new heights across the globe.

Learn more about the available Sponsorship & Exhibits opportunities.

The latest issue of Diseases of the Esophagus Journal is now available online.

Subscribe to DOTE email alerts.
Evaluation of tumor regression by neoadjuvant chemotherapy regimens for esophageal adenocarcinoma: a systemic review and meta-analysis
  • Locally advanced esophageal adenocarcinomas (EACs) are treated with multimodal therapy.
  • A meta-analysis was performed including 22 studies that described tumor regression post-NAC, comparing the pathological complete response (pCR) after FLOT, non-FLOT-based chemotherapy and chemoradiotherapy (CRT) regimes in patients with EACs.
  • Altogether, 1,056 patients had undergone FLOT or DCF regimes, while 1,610 patients had received ECF or ECX.
  • The pCR rates ranged from 3.3% to 54% for FLOT regimes, and 0% and 31% for ECF/ECX protocols.
  • Pooled random-effects meta-meta-analysis of proportions showed a statistically significant higher incidence of pCR in FLOT-based chemotherapy at 0.148 (95%CI: 0.080, 0.259) compared with non-FLOT-based chemotherapy at 0.074 (95%CI: 0.042, 0.129). The pCR rates were significantly highest at 0.250 (95%CI: 0.202, 0.306) for CRT.
  • The use of enhanced FLOT-based regimens have improved the pCR rates for chemotherapeutic regimes but still falls short of pathological outcomes from CRT.
Call for Nominations:
DOTE Best Junior Faculty/Trainee
Manuscript Award

The Editors of Diseases of the Esophagus (DOTE) Journal are pleased to invite submissions for the 2022 Best Junior Faculty/Trainee Manuscript Award. This award recognizes the top original research manuscript by a junior faculty or trainee author accepted for publication in the Journal between January 1 and December 31, 2022.

Nomination Deadline: April 7, 2023

The Journal also has an award for the most Outstanding Junior Faculty Peer Reviewer each year, and winners are determined by the Co-Editors-in-Chief based on the number of peer reviews completed, timeliness and quality of the peer review. Are you interested in becoming a Diseases of the Esophagus reviewer? If yes, register for the peer review process and create an account in the Scholar One manuscript managing system.

Visit DOTE Awards page for more information or contact membership@isde.net.
Early career membership rates are now available for individuals with less than five (5) years consultancy.  Early career members can access all the benefits for 30% less or more than the full member rate. Special rates are also available for colleagues in developing countries, and benefits include:

  • Join a community of like-minded professional peers
  • Receive member-only updates and invitations to educational events or research surveys
  • Enjoy an electronic subscription to the Diseases of the Esophagus Journal
  • Discounted rates to the 2023 ISDE World Congress in Toronto, Canada from September 8-10, 2023
Literature Updates











Visit the ISDE Literature Updates Online for more.
Digestive Disease Week 2023 - May 6-9, 2023 (Chicago, IL)
International Robotic Association (UGIRA 2023) - June 9-11, 2023 (Taipei, Taiwan)

International Gastric Cancer Congress 2023 - Jun 14-17, 2023 (Yokohama, Japan)

International Society for Diseases of the Esophagus (ISDE) - September 8-10, 2023 (Toronto, Canada)
Additional events of interest to the ISDE members and community can be found on the ISDE Other Events Calendar.
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CONTACT US: membership@isde.net | 604.638.3862