Seminars

RNA Innovation Seminar Series Returns January 22, 2024 - Save the Date!

RNA Innovation Seminar Series

Anthony Rosenzweig, Ph.D.

Professor of Internal Medicine

Director of the MM Institute of Heart & Brain Health

University of Michigan

"Talk Title TBD"

Monday, January 22, 4:00 PM - 5:00 PM ET

BSRB ABC Seminar Rooms, Hybrid Link

Upcoming Affiliated Seminars

U-M Chemistry Seminar Series

"Molecular consequences of deregulated rRNA processing and modification in biology and disease"

Homa Ghalei

Associate Professor of Biochemistry

Emory University School of Medicine

Hosted by Professor Kristin Koutmou

Tuesday, December 12, 2023

4:00-5:15 PM, 1200 Chemistry Dow Lab

RESCHEDULED: BioInnovations in Brain Cancer Seminar Series

"Gene therapy for brain tumors: immune, cytotoxic, and novel long-term physical approaches"

Speaker: Dr. Pedro Lowenstein, M.D., Ph.D.

Faculty Member, CRB

Thursday, December 14, 4:00-5:00 p.m.

NCRC, B32 Auditorium. The seminar will be held in person.

U-M Life Sciences Institute Structure Seminars

"UM Structure Seminar: Mechanistic insights into the alternative ribosome recycling by HflXr"

Friday, December 15, 2023

10:00 AM to 11:00 AM | LSI Library

Speaker: Savannah Seely, Ph.D. Student

University of Texas Medical Branch

Host: Jay Brito Querido, Jay Brito Querido Lab

HMS Initiative for RNA Medicine Seminar Series

"tRNA-derived small RNAs: novel functions in cellular stress response and disease pathways"

Saumya Das, MD, PhD , Associate Professor of Medicine, Harvard Medical School, Director of Resynchronization and Advanced Cardiac Therapies, Cardiac Arrhythmia Service, Mass General Hospital

Tuesday, December 19^th, 2023 | 3:00 – 4:00 PM EST

Join us In-Person at Center Life Science Building (421) OR To Join Virtually Click This Link

RNA Research Centre in Poznań

Speaker Jakub Dolata, Postdoctoral Research, “microRNA biogenesis: co-transcriptional regulation and RNA modifications”

Speaker Zbigniew Warkock, PhD Postdoc, "LINE-1 mRNA 3’ end dynamics shape its biology and retrotransposition potential"

Moderator: Magda Maslon, PhD

Wednesday, December 20, 2023, 10 AM CET  Zoom Registration

Other Events

Dr. Catherine Kaczorowski Professorship Installation

"Using Complex Genetics in Mice to Unlock the Secrets of Resilience to Dementia."

Join us for the installation of Dr. Catherine Kaczorowski as the Elinor Levine Professor of Dementia Research in Neurology. Dr. Kaczorowski is also a Faculty Member of The Center for RNA Biomedicine.

TODAY, Monday, December 11

4:00 PM TO 5:00 PM, BSRB Kahn Auditorium

Hosted by the Department of Neurology. There will be a reception immediately following the presentation.

Oral Defenses

U-M Oral Dissertations

RNA SOCIETY

New Blog Post: Lexogen RNA Expertise Blog Series

In the News

FDA Approves Two Sickle Cell Gene Therapies Including First CRISPR Drug

The US Food and Drug Administration on

Friday approved the first two gene therapies to treat

patients with sickle cell disease (SCD), including the first-

ever drug approved using CRISPR gene-editing technology.

Read the full story in Precision Medicine Online.

Poster Session || 8th Annual Symposium - U-M Graduates and Postdocs

As in years past, we will have an opportunity for trainees to present their work in the form of a poster session midway through the day, with the option of participating in one of several lighting talk sessions for a chance to introduce their work prior to the poster session.

Submissions are now open!

Open to current University of Michigan graduate students and postdoctoral scholars. Applicants outside of the University of Michigan may be considered on a rolling basis if time slots remain vacant.

Stephen Parker co-lead author of new paper linking gene network and pancreatic beta cell defects to type 2 diabetes

Center for RNA Biomedicine Faculty and Executive Committee Member Stephen C.J. Parker, Ph.D., Associate Professor, Departments of Computational Medicine & Bioinformatics, Human Genetics, and Biostatistics, just released new findings from a recent study on type 2 diabetes regulatory networks co-led by teams from the University of Michigan and Vanderbilt University. Read the full story.

Watch 2023 Nobel Prize lectures in physiology or medicine | Katalin Karikó and 2024 RNA Symposium speaker Dr. Drew Weissman | December 7, 2023

Meetings

There's Still Time to Join Us for the Joint Meeting on RNA Modifications and Regulatory RNAs

Click the photo above to download the program flyer.

Keystone Symposia's joint meeting on RNA Modifications in Health and Disease and Regulatory RNAs: Emerging Mechanisms is coming up this December 12-15 in Banff, AB, Canada. Even though most deadlines have passed, we want to let you know that it's not too late to register for two conferences for the price of one!

For more information and to register, visit: Keystone Symposia

Nucleic Acid Delivery to Cancer

Presenter: Zdravka Medarova, PhD; Co-Founder & CTO

Company: TransCode Therapeutics, Inc.

Moderator: Frank Slack, PhD, Director of the HMS Initiative for RNA Medicine

Tuesday, December 12^th, 2023 | 3:00 – 4:00 PM EST

Join us In-Person at Center Life Science Building (421) OR Join Virtually

Contact Glee8@bidmc.harvard.edu for more details.

HIRM 2024 Symposium, April 25 - Save the Date

2024 Symposium

HIRM 10 Year Anniversary Symposium

Thursday, April 25, 2024

Joseph B. Martin Conference Center

77 Avenue Louis Pasteur

Boston, MA 02115

Our members' publications are available through Altmetric. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.

Below are recent highlights. Bold denotes CRB member.

Hatfield BM, Weidmann CA, Weeks KM. Measuring Proximity-Mediated Function of mRNA Regulatory Proteins by Engineered Tethering. Methods Mol Biol. 2024;2723:143-159. doi: 10.1007/978-1-0716-3481-3_9. PMID: 37824069; PMCID: PMC10621603. https://doi.org/10.1007/978-1-0716-3481-3_9

Goutman SA, Boss J, Jang DG, Mukherjee B, Richardson RJ, Batterman S, Feldman EL. Environmental risk scores of persistent organic pollutants associate with higher ALS risk and shorter survival in a new Michigan case/control cohort. J Neurol Neurosurg Psychiatry. 2023 Sep 27:jnnp-2023-332121. doi: 10.1136/jnnp-2023-332121. Epub ahead of print. PMID: 37758454. https://doi.org/10.1136/jnnp-2023-332121

Smith TJ, Giles RN, Koutmou KS. Anticodon stem-loop tRNA modifications influence codon decoding and frame maintenance during translation. Semin Cell Dev Biol. 2024 Feb 15;154(Pt B):105-113. doi: 10.1016/j.semcdb.2023.06.003. Epub 2023 Jun 28. PMID: 37385829. https://doi.org/10.1016/j.semcdb.2023.06.003

Wilhelm CA, Mallik L, Kelly AL, Brotzman S, Mendoza J, Anders AG, Leskaj S, Castillo C, Ruotolo BT, Cianfrocco MA, Koutmos M. Bacterial RNA-free RNase P: structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P. J Biol Chem. 2023 Oct 6:105327. doi: 10.1016/j.jbc.2023.105327. Epub ahead of print. PMID: 37806495. https://doi.org/10.1016/j.jbc.2023.105327

Hou Q, Chatterjee S, Lund PE, Suddala KC, Walter NG. Single-molecule FRET observes opposing effects of urea and TMAO on structurally similar meso- and thermophilic riboswitch RNAs. Nucleic Acids Res. 2023 Oct 19:gkad866. doi: 10.1093/nar/gkad866. Epub ahead of print. PMID: 37855661. https://doi.org/10.1093/nar/gkad866

Job Postings

Postdoctoral Fellow UMich Department of Pathology

The laboratory of Dr. Sethu Pitchiaya, Assistant Professor, Department of Urology, Department of Pathology at the University of Michigan seeks to hire an enthusiastic Postdoctoral fellow to work on exciting projects related to mammalian stress response mechanisms. Learn more.

University of Michigan BIBC Tenure Track Faculty Search

The University of Michigan has launched a Tenure Track Faculty Search for the BioInnovations in Brain Cancer Initiative (BIBC), led by Center for RNA Biomedicine Faculty Member Dr. Maria G. Castro and Dr. Steven Schwendeman. Learn more.

The University of California Irvine (UCI), Department of Ophthalmology

Full-Time Position

Inviting applicants focused on the development of genetic engineering and genome editing technologies. Learn more.

Postdoctoral Research Fellow and Graduate Research Assistants

Dr. Guizhi (Julian) Zhu Lab | University of Michigan

Multiple full-time openings for Postdoctoral Research Fellow and Graduate Research Assistants. Learn more.

Research Technician and Post-Doctoral Research Fellow | Fred Hutchinson Cancer Center | The Lapointe Lab

Seeking to fill two positions: Research Technician and Post-Doctoral Research Fellow. Learn more.

Research Technician - Yadavalli Lab

Seeking full-time technician or research scientist to perform cutting-edge research in RNA biology using high-throughput sequencing methods. Learn more.

Postdoctoral Position - Maquat Lab

A postdoctoral position is open. Applicants should hold a PhD or MD/PhD degree(s) and have expertise in molecular, cellular, or structural biology. Learn more.

Postdoctoral Position - Cooperman Laboratory

Seeking postdoctoral student with a strong interest in understanding the mechanism and regulation of cytoplasmic eukaryotic protein synthesis. Learn more.

For complete details on current openings and how to apply for these positions, visit the Recruitment Opportunities page on our website

Save the Date

2024 RNA Symposium | March 8, 2024 - Registration is now open!

Unmasking the Power of RNA: From Structure to Medicine

To share your news and comments, please contact

rna-communications@umich.edu