(with corrected link!) Trajectory Explorer for Neural Probe Insertion

NEW SCALE NEWS

LIFE SCIENCE LAB AUTOMATION EDITION

June 2022

Dear Colleague,

Sorry about that broken link in the "read the article" button. Here's a corrected copy! (If it still doesn't work please click on the image instead.)

Planning insertion trajectories for neural probes may be getting a bit easier. For the past six months we've had the privilege of collaborating with researchers at University College London, the Allen Institute, and the University of Washington as they refined their trajectory planning tools and frameworks. We're excited at how these open-source tools can work hand-in-hand with our software and hardware for probe insertion. Check it out below, and please let us know what you think!

-Ed Friedrich and the MPM Team at New Scale Technologies

ARTICLE

Neural Probe Trajectory Planning & Automated Insertion

IMAGE - SCREEN SHOT OF ANDY PETERS' TRAJECTORY EXPLORER SOFTWARE

Andy Peters at University College London has developed Trajectory Explorer software to help define the optimal insertion path for silicon neural probes in mice (and now rats, too). This software can output 3D atlas start point coordinates (ap,ml,dv) and end point coordinates (ap,ml,dv) for the chosen insertion path.

When these coordinates are entered into New Scale's MPM Multi-Probe Manipulator Virtual Coordinate System (VCS), the VCS software automatically calculates the setup parameters for the manipulator hardware (polar and pitch angles, arm height and length) required to hit that trajectory.

Both the Trajectory Explorer and the VCS software work within the Allen Common Coordinate Framework (Allen CCF).

Andy Peters developed the Trajectory Explorer as a neuroscience postdoc in the Carandini/Harris lab at University College London. The article includes links to his github repository and his lecture demonstrating the software.

READ THE ARTICLE

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New Scale Technologies develops and manufactures the smallest and most precise closed-loop positioning solutions available. Our “all-in-one” M3 Smart Modules with built-in controllers are easy to integrate with handheld and portable instruments. We enable smaller, smarter imaging systems, scientific instruments, medical devices, aerospace and defense systems and more. Our customers achieve the fastest results with the lowest total cost.

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