ICRF receives Four-Star rating from Charity Navigator |
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ICRF is proud to announce that we have received a 97% rating from Charity Navigator, earning us a highly sought-after four-star rating. Four stars is the highest possible rating on Charity Navigator. For over twenty years, Charity Navigator has been helping people determine whether giving to a particular charity is a good investment by rating them on financial stability, efficiency, and sustainability. Charity Navigator’s third-party accreditation confirms our organization’s operational excellence. |
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'Complete' synthetic models of human embryos created from stem cells in labs |
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Professor Jacob Hanna, ICRF-Nikoh Foundation Research Professorship Grant recipient, and his team have successfully grown “complete” synthetic models of human embryos outside of the womb up to day 14. This has potential implications in many different areas of science, including cancer research and the quality of life for cancer patients by potentially leading to new technologies for growing transplant tissues and organs.
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October is Breast Cancer Awareness Month, and it also sees the start of Global Brain Tumor Awareness Week, which runs from October 28 to November 4. This month, we chose to focus on the incredible work of ICRF researchers who are making groundbreaking progress in treatment and therapy in the fields of brain and breast cancer.
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Unlocking the Power of the Mind: Training the Brain to Defend Against Breast Cancer Pain |
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Tami Bar-Shalita, PhD and Yelena Granovsky, PhD
Tel Aviv University and Rambam Health Care Campus
The ICRF – Redhill Foundation Project Grant
Train the brain for pain: In Israel, some 4,000 new breast-cancer cases are diagnosed annually. Survivorship is increasing due to hormonal therapy, but many patients develop pain and cognitive impairment as side effects of such treatment. Given that pain and cognition are linked both behaviorally and in brain activity, Dr. Bar-Shalita and her colleagues are exploring neurofeedback therapy, a non-invasive and non-pharmacological treatment that may prevent worsening clinical symptoms by training the brain.
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From a clinical perspective, since breast cancer survivors are struggling to return to previous roles, functioning, and quality of life, this research project may elicit a novel therapeutic modality which will enhance quality of life and function in breast cancer survivorship.
Dr. Tami Bar-Shalita
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Spotlight on ICRF Researchers |
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Hebrew University of Jerusalem
The ICRF – Joseph Safra Memorial Grant for Glioblastoma Research
PROS1, a protein that helps regulate blood clotting, has been linked to specific diseases and conditions. The Burstyn-Cohen research team found a correlation between aggressive brain tumors (glioblastomas, or GBM) and PROS1 overproduction, and discovered that blocking PROS1 production makes GBM more sensitive to radiation and chemotherapy. The team’s current experimental study aims to further understand how PROS1 supports brain tumors, which may sensitize GBM and make treatment more beneficial.
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Technion - Israel Institute of Technology
Project Grant
Immunotherapy has become a significant and promising treatment modality in some cancers, due to its substantial therapeutic activity at advanced-staged cancer. But only 20-40% of patients respond to immunotherapy and in some cases, the treatment causes tumors to metastasize. Dr. Shaked and his team will study the mechanisms involved in the risk of developing brain metastases in immunotherapy-resistant patients. This study should help optimize immunotherapy and potentially reduce its terminal side effects.
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Tel Aviv University
The ICRF – Redhill Foundation Project Grant
Eosinophils, white blood cells that support the immune system, can fight parasitic infections by inducing cell death and damage. Dr. Munitz and his team have shown that eosinophils are also recruited and activated in breast cancer that has metastasized to the lung, where they have potent anti-tumor activity. The researchers are currently studying a molecule identified as a potential regulator of eosinophil activity, which should eventually lead to new treatments, especially in lung metastasis.
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Metastasis occurs when cancer cells from a primary tumor break away and travel to other parts of the body through the bloodstream or lymphatic system. Once they reach these new locations, they can start growing and form secondary tumors. This is a critical step in the spread of cancer and makes it more challenging to treat because there may be tumors in multiple areas of the body. Understanding and controlling metastasis is a crucial focus in cancer research and treatment. |
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Connecticut Tower of Hope Gala
Join us as we gather together to celebrate members of our community (Leslie Freedman, PhD – Tower of Hope Honoree and Rabbi Mitch Hurvitz, Community Hero Honoree) in support of cancer research and the hope that it brings to us in our mission to end the suffering caused by cancer. Emcee: comedian Judy Gold.
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New York Tower of Hope Gala
Join special guest host Lizzy Savetsky and Nobel Laureate Avram Hershko, MD, PhD for a joyous night of entertainment, science and hope at the Harvard Club in NY.
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Chicago Tower of Hope Gala
Coming together for a cure! Join us for an entertaining and enlightening evening to celebrate science and hope. ICRF Chicago is proud to honor Jennifer McGuffin (Humanitarian Award) and Richard Herman (Leadership Award) at this year's gala.
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Deceptive Health Advice on TikTok Raises Concerns About Gynecologic Cancer Misinformation (GeneOnline) A recent study from The Ohio State University Comprehensive Cancer Center (OSUCCC) – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute has raised concerns about the volume of misinformation about gynecologic cancers on TikTok after doing a study of the top 500 posts on the platform on the topic and determining that over 70% of the information being disseminated was inaccurate.
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Double the Impact of Your Tax-Deductable Gift |
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Did you know that you can double the impact of your tax-deductible gift to ICRF by taking a few seconds to check if your employer will match your gift?
This means that your gift + your employer's match can = 2x the impact on groundbreaking cancer research.
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With a planned gift to the Israel Cancer Research Fund (ICRF), you can make a meaningful impact on countless cancer patients and their loved ones for years to come. To learn more about including ICRF in your estate planning, please contact Alan Herman at alan.herman@icrfonline.org or call 347-218-5946.
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