Dear Jeannette ,

Check out our latest WCMC Newsletter!

- WCMC Outreach Core

We here invite papers on research products that have been performed in collaboration with the WCMC faculty members or using the WCMC service core for data acquisition. We will highlight the many facets of our research, covering method development, informatics, basic biology, and biomedical applications. Topic areas range from fundamentals in compound identification to data normalization, and statistics, to various applications in biology and biomedicine. Applications include studies on human glioblastoma, sexual dimorphisms of mouse knockouts, gut microbiome studies, and others. Submissions of manuscripts focusing on the function and regulation of lipids are especially welcome.

Deadline: August 17, 2023

Information on this issue of Metabolites can be found here.

Metabolites Impact Factor is 4.1

Date: August 21 - September 1, 2023

Virtual Instructor-Led Course (Online)

There's still time to register for this 2-week course! The course will feature hands-on training with real-world untargeted metabolomics data covering all parts of the metabolomics workflow from A to Z, including:

• Study design, including pitfalls and hidden biases.
• Sample preparation and quality control
• Untargeted data processing and exercises on MS-DIAL.
• Exercises in the identification of unknowns by cheminformatics software workflows
• Data normalization and transformation with and without internal standards and quality controls
• Multivariate and univariate statistics 
• Pathway mapping and enrichment analysis

We look forward to seeing you there!

Bits & Bites # 05: Identification of unknown compounds in untargeted metabolomics using freely available software

Sept. 7, 2023 @ 9 am - 5 pm PT

Instructor: Dr. Arpana Vaniya, UC Davis

About this course:

• Compound identification is a bottleneck in metabolomics.
• Approaches to tackle this challenge: mass spectral library search, in silico fragmentation tools, and database searching.
• Short course overview: Current status of compound ID in metabolomics.
• Learn to use freely available in silico fragmentation tools: MS-FINDER and SIRIUS+CSI: FingerID, web-based tools like MetFrag and CFM-ID.
• Apply learned skills to unknown challenges.

Bits & Bites #06: Mass Spectrometry for Metabolomics is coming up on October 5, 2023 Instructor: Dr. Uri Keshet

September 8, 2023

9 am to 2 pm PT

Register for free here

Hosted by UC Davis West Coast Metabolomics Center | Online

• Come join us for the 5th Annual MANA Fall Symposium: "Expanding the Exposome: The Power of Mass Spectrometry."
• Learn from impressive lineup of speakers sharing latest exposome research insights.
• Discover how mass spectrometry explores environmental exposures throughout life.
• Stay updated on field advancements and connect with environmental health professionals.
• Join us for a rewarding symposium experience!

• Bremer, P. L., et al.. The BinDiscover database: a biology-focused meta-analysis tool for 156,000 GC–TOF MS metabolome samples. Journal of Cheminformatics 15.1 (2023): 1-14.
• Rodríguez, Elys P., et al. Alternative Identification of Glycosides Using MS/MS Matching with an In Silico-Modified Aglycone Mass Spectra Library. Analytical Chemistry (2023).
• Martin-Pelaez, Soledad, et al. Effect of pentobarbital as a euthanasia agent on equine in vitro embryo production. Theriogenology 205 (2023): 1-8.4
• Chen, Mingjing, et al. Longitudinal Lipidomic Profile of Hypertension in American Indians: Findings From the Strong Heart Family Study. Hypertension (2023).

UC Davis West Coast Metabolomics Center

451 Health Sciences Dr. Rm 1313

Davis, CA 95616

Phone: (530) 752-8129

If you have any questions contact us: metabolomics@ucdavis.edu