Wednesday, December 7, 2022

12:00PM-1:00PM

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“Neuropathological Correlates of Small Vessel Disease Neuroimaging Markers in Cerebral Amyloid Angiopathy”

Susanne J. van Veluw, Ph.D.

Assistant Professor in the Department of Neurology

Massachusetts General Hospital / Harvard Medical School


Dr. Susanne van Veluw is an Assistant Professor in the department of Neurology at Massachusetts General Hospital (MGH) / Harvard Medical School. She received her PhD from the University Medical Center in Utrecht, the Netherlands, under the supervision of her thesis advisor Dr. Geert Jan Biessels. During her PhD, she used high field 7 tesla MRI and neuropathological examination in brain tissue of older individuals to study the impact of microvascular pathology on brain structure and cognitive function. For her post-doctoral training, she moved to Boston to work on cerebral amyloid angiopathy (CAA) with Drs. Steven Greenberg and Brian Bacskai at MGH. She joined the Neurology faculty at MGH in 2020. Her lab uses translational imaging approaches, ranging from ex vivo MRI-guided histopathology in human brain tissue to in vivo two-photon microscopy in mice to better understand the pathophysiology of sporadic and hereditary CAA. In particular, the Van Veluw lab is interested in unraveling the mechanisms of hemorrhage formation in CAA and the driving force of perivascular β-amyloid clearance, with the goal to find novel targets for therapeutic intervention aimed at preventing hemorrhagic stroke and cognitive impairment in patients with small vessel disease.


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