The RNA Transcript, May 30, 2022 |
|
Announcing the 2022 RNA Research Scholar Exchange Awardee.
|
|
|
|
Liz will be visiting the Jinwei Zhang Lab in the NIDDK. Jinwei Zhang, an expert in RNA crystallography and experimental phasing with heavy metal soaking. This experience will considerably enhance Liz’s training as well as give her insights on a current project that has a challenging experimental phasing issue on a structurally novel RNA that she crystallized. We are thrilled to support this project and look forward to learning more about Liz’s visit next year. |
|
|
|
The goal of The RNA Function is to connect students and postdocs from across the university in an informal and low-risk environment to hear what other groups are doing around campus. Trainees of all levels will gain in-person poster presentation experience and learn about the many areas of RNA-related expertise on campus. We encourage everyone to present a poster that they have from a previous symposium or conference, and co-presenting by multiple members of a lab is supported. Finally, a facilitated networking event will allow trainees to make meaningful connections, with an emphasis on brainstorming ways in which cross-lab collaborations can propel projects forward.
--Thursday, June 9, 2022
--ABC Seminar rooms, BSRB
--Agenda
----12:00 – 1:30 Lunch & poster session
----1:45 – 3:00 Networking event
|
|
Registered in-person participants will receive a free box lunch. Please register by May 31st
|
|
|
|
27th Annual RNA Society Meeting
May 31 to June 5, 2022
Boulder, Colorado (in-person)
|
|
RNA Collaborative Seminar Series |
|
----Wednesday, June 1, 2022
----10:00 am - 11:00 am
|
|
SARS-CoV-2 nucleocapsid protein-RNA interactions encode viral functions
Counterbalanced interactions between DNA regulatory elements control long-distance epigenetic silencing by the Airn lncRNA
|
|
|
U-M Mary H. Weiser Food Allergy Center |
|
|
|
Advancing the Science of Food Allergy
Offers an outstanding program featuring 15 esteemed biomedical experts and thought leaders in clinical and basic research
June 1-2, 2022
BSRB
|
|
U-M Oral Dissertation Defense |
|
|
|
Mechanistic Insight Into the Role of Gut Bacterial Functional Amyloids in Modulating α-Synuclein
Friday, June 3, 2022
10:00 - 11:00 AM
BSB 1010
|
|
U-M CRYO-EM Summer Workshop |
|
|
|
I have my data set — Now what?
Participants will be introduced to common image processing packages used to analyze cryo-EM data.
June 5 - 9, 2022
LSI Building
|
|
U-M Oral Dissertation Defense |
|
|
|
Molecular Mechanisms of Subcellular Development: Down Syndrome-Related Genetic Interactions and Axon-Dendrite Coordination During Neurodevelopment
Monday, June 6, 2022
10:00 - 11:00 AM
Palmer Commons, Forum Hall
|
|
U-M Center for RNA Biomedicine RNA Innovation Seminar |
|
|
|
Long non-coding RNAs as evolutionarily fluid chromatin weavers
Monday, June 6, 2022
4:00 pm - 5:00 pm
|
|
U-M Center for Cell Plasticity and Organ Design (CPOD) |
|
|
|
Genetic regulation of epithelial homeostasis and injury
Tuesday, June 7, 2022
4:00 pm - 5:00 pm
|
|
U-M RNA Student Postdoc Council |
|
|
|
The RNA Function
A networking event designed for U-M students and postdocs from across the university to hear what other groups are doing around campus
Thursday, June 9, 2022
12:00 - 3:00 pm
BSRB, ABC Seminar rooms
|
|
|
|
Join the Taubman Scholars at Ann Arbor Summer Festival
Thursday, June 23, 2022
5:30 - 8:30 pm
Taubman Tent at the Ann Arbor Summer Festival
|
|
|
|
Pfizer is seeking proposals for the advancement of therapeutics in renal disorders
|
|
Open for Submissions: April 25th - June 13th, 2022 |
|
|
|
Catalyzing translational research efforts by supporting preclinical and commercial clinical development |
|
Innovation Partnerships at the University of Michigan manages Great Lakes Discovery, a ten-year collaboration with Deerfield Management Company, L.P to fund U-M drug discovery from early-stage research to clinical development.
-
Deerfield has committed up to $130 million over the next decade to invest in biomedical research at U-M with the aim of developing potentially life-saving drugs and disease treatments.
-
Projects selected by Great Lakes Discovery will be provided funding and operational support through a development plan aimed at achieving Investigational New Drug (IND) readiness.
GET STARTED WITH A CONSULTATION There is no open Request for Proposal (RFP) - the first step for an interested researcher is to schedule a consultation with the program’s Scientific Collaboration Manager Dr. Seohee You (shyou@umich.edu).
|
|
|
|
Pfizer is looking for a Senior Scientist
in mRNA Vaccine Development
|
|
We are looking for a Senior Scientist who will work on various aspects of mRNA production for the Upstream Development Group within Early Bioprocess Development at VRD in Pearl River, NY. The incumbent will work on current generation mRNA production, but also innovate, develop and optimize methods to further the state of the art in generating high quality mRNA. This development work will be pursued in the context of producing RNA both at lab scale and upwards. A strong, hands-on background in mRNA generation is required, including in vitro transcription, as well as in general molecular biology and biochemistry. There would be special interest in candidates with a strong biochemical, biophysical, and/or structural biology background in the context of mRNA. The incumbent would be joining a team of scientists well-versed in mRNA production, and would both lead and support efforts with the team. Apply here
|
|
|
|
Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation. Below are recent highlights.
|
|
Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP, S. W. Olson, A. W. Turner, J. W. Arney, I. Saleem, C. A. Weidmann, D. M. Margolis, K. M. Weeks, A. M. Mustoe, (2022) Molecular Cell. 10.1016/j.molcel.2022.02.009
Highlights
- DANCE-MaP enables complete characterization of RNA structural ensembles in cells
- The 7SK RNA encodes a large-scale structural switch that modulates P-TEFb binding
- 7SK structure switches dynamically in response to cell growth and stress
- The 7SK switch is a potential therapeutic target for modulating transcription
Keywords: DANCE-MaP; ensemble deconvolution; noncoding RNA; transcriptional regulation; cancer; HIV
|
|
|
|
|
|
|
