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Dear Colleagues,
Congratulations to our DOM faculty who were elected to the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP). As a reminder, Steve Schroeder and the DOM awards committee are available to assist with nominations for AAP, ASCI and other honors. Please also join us in congratulating two of our DOM faculty on their recent K-awards, found in the Career Development section below. Last, we’d like to point out two upcoming symposia, highlight Advanced Research Projects Agency for Health (ARPA-H), a new federal agency that supports team approaches for solving major health challenges, and draw your attention to many new and continuing funding opportunities.
All the best,
Diane Havlir, MD, Associate Chair for Clinical Research
David Erle, MD, Associate Chair for Biomedical Research
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Election to the American Society for Clinical Investigation (ASCI) | |
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Congratulations to Babak Javid and Elad Ziv who were elected to the American Society for Clinical Investigation (ASCI), a society that seeks to support the scientific efforts, educational needs, and clinical aspirations of physician-scientists to improve the health of all people.
To read more about their research, see below.
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Babak Javid, PhD, is a professor in the Division of Experimental Medicine at ZSFG. His research focuses on fundamental mycobacterial pathophysiology, regulation of adaptive protein synthesis, molecular mechanisms of antibiotic tolerance, and human humoral immunity to tuberculosis.
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Elad Ziv, MD, is a professor in the Division of General Internal Medicine at UCSF Health. His research focuses on the genetic epidemiology (how inherited factors play a role in disease) of breast cancer and other age-related diseases. He also studies groups of mixed ethnicity to understand the relationship between environmental and genetic risk factors in explaining differences in cancer incidence.
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Election to the Association of American Physicians (AAP) | |
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Michelle Albert, MD, MPH, is a professor in the Division of Cardiology at UCSF Health. Her research focuses on both taking care of the most critically ill heart disease patients and preventive cardiology at UCSF. Her research has followed a bold, non-traditional path for cardiovascular disease research. A central component of her current work focuses on developing innovative implementation strategies to curb adversity-related CVD risk, particularly in women and diverse racial and ethnic populations with a focus on cumulative toxic stress.
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Priscilla Hsue, MD, is a professor and Chief in the Division of Cardiology at ZSFG. Her research focuses on cardiovascular complications of cocaine including aortic dissection, myocardial infarction, and cardiac arrest. She also focuses on the pathogenesis of atherosclerosis in HIV-infected patients treated with antiretroviral therapy, clinical features and outcomes of acute coronary syndromes, incidence and mechanisms of pulmonary hypertension, and dyslipidemia, all in HIV-infected patients.
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Karla Kerlikowske, MD, is a professor in the Division of General Internal Medicine at SFVAHCS. Her research focuses on Women’s health, breast cancer, ductal carcinoma in situe, breast imaging, cancer screening, breast cancer risk prediction, cancer prevention, disease recurrence, biomarkers, breast density, decision-analysis.
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Christian Vaisse, MD, PhD, is a professor in the Diabetes Center. The overall goal of his laboratory is to identify genetic defects implicated in the onset and progression of multi-factorial metabolic diseases such as obesity and diabetes. He is currently concentrating his research on the molecular mechanisms implicated in the hypothalamic effects of the adipocyte-secreted, weight-regulating hormone, leptin.
| Steve Schroeder, MD and the DOM awards committee are available to assist with nominations for AAP, ASCI and other honors. For questions, please contact Steve Schroeder or Ilona Paredes. | |
Career Development Awards | |
Career Development Resource | |
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UCSF ARCHES: Advancing the Research Careers of Historically Excluded Scholars
The ARCHES Program (Advancing the Research Careers of Historically Excluded Scholars) is a career development program for historically excluded (HEx) research faculty that was built recognizing that diversity is critical to institutional success and scientific progress, and that representative role models positively impact junior faculty and trainees. The overarching goal of this program is to support and retain current research faculty who come from HEx backgrounds, both professionally and personally. We want to help them become scientific leaders in their fields and partners in driving systemic policy change that promotes a culture of inclusive excellence.
ARCHES Community Organized Informal Networking events (COINs) are cross-departmental, in-person networking, and peer mentorship opportunities for you to connect with colleagues in small group settings. As part of the ARCHES community, you are encouraged to submit an event to host and/or participate in to connect and expand your network and community.
The ARCHES Program also hosts quarterly seminars aimed at early career research faculty on topics such as mentorship, advancement, finances, and more. To access the seminar and resource pages, click here.
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UCSF Promoting Research in Social Media and Health Symposium (PRISM)
Applications are due by May 30
You are invited to attend the Promoting Research in Social Media and Health Symposium (PRISM), one of the few symposiums dedicated to social media and health research on Thursday, December 7, 2023. An all-day event that fosters a collaborative learning environment, PRISM provides a one-of-a-kind opportunity for participants to meet, collaborate, and advance their work.
Corresponding authors for each selected abstract will be notified on Friday, July 14, 2023.
To view the PRISM 2022 highlights, click here.
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UCSF Academic Senate Committee on Research
Applications are due by June 9
The Academic Senate Committee on Research is accepting nominations for the 2023-2024 Faculty Research Lectures. These awards acknowledge the outstanding scientific achievements made by members of the UCSF Academic Senate in Basic Science, Clinical Science, and Social, Behavioral, and Health Policy Sciences. Translational researchers may be nominated in either the Basic Science or Clinical Science category, depending on which is the better fit for their research. Nominators are asked to state the best-fitting category for the candidate’s research within the cover page of the application. A list of prior recipients and detailed instructions for nomination packets may be found on the Senate website. Nominations should be submitted via the Senate service portal. For questions, please contact Liz Greenwood. We especially encourage nominations from historically excluded groups and those underrepresented in medicine and science.
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Updated DOM NIH+ Guidelines | |
Bob Wachter hosted two Town Halls this past week to share the rationale for some changes in DOM clinical and research programs in the coming year. Bob described the rationale for these changes, and David Erle and Diane Havlir described modifications of the NIH + program for this coming fiscal year. For an up-to-date synopsis of the eligibility and support from the iRAPS and NIH+ programs, click the button below. For questions, please contact David Erle or Diane Havlir. | |
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EXTRAMURAL The Advanced Research Projects Agency for Health (ARPA-H)
Applications are due by March 14, 2024
The Advanced Research Projects Agency for Health (ARPA-H) is a new federal agency that supports team approaches for solving major health challenges. The ARPA model is quite different than the traditional NIH model. Rather than supporting research on specific diseases, ARPA-H will support high-risk, high-consequence programs designed to improve health for everyone. Examples provided by the agency:
Imagine if…
- Cell therapies could be built and assembled on demand, readily reprogrammed for each new disease target
- MRIs could be delivered in the comfort of your home
- A personalized cancer vaccine cost the same as a cup of coffee
There are various ways to become involved in ARPA-H research:
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Become an ARPA-H Program Manager. Those selected as Program Managers take leave from UCSF for three to six years to become full-time ARPA-H employees and run large (typically ~$50-150M) efforts with business and technical support and the authority to assemble and fund multidisciplinary teams from industry, academics, and government. Program managers need not relocate to take on this role.
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Once Programs are launched, respond to a Program Manager’s call for proposals. Program Managers will issue Broad Agency Announcements (BAAs) requesting proposals for work related to that program.
- Become involved in development, scaling up, or production as projects progress.
- Lead an “Open BAA” proposal. In advance of the launch of ARPA-H Projects, specific proposals with a narrower scope that address the goals of ARPA-H can be submitted from now until March 14, 2024. These may eventually be incorporated into ARPA-H programs.
To learn more about ARPA-H and how to apply to become a Program Manager or respond to a BAA, visit the UCSF Research Development Office ARPA-H website, which includes links to videos and slide decks with more information.
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Reminder Extramural NIH High-Risk, High-Reward Research Program
Various deadlines, see below
The NIH Common Fund announces FY 2024 funding opportunities for the NIH Director’s New Innovator Award, Transformative Research Award, and Early Independence Award in the High-Risk, High-Reward Research program. The program provides unique opportunities for exceptionally creative scientists to pursue highly innovative approaches to address major challenges in biomedical or behavioral research. Any research topic relevant to the broad mission of NIH is welcome.
NIH strongly encourages applications from women and members of groups that are underrepresented in NIH-funded research and from individuals from diverse backgrounds and from the full spectrum of eligible institutions in all geographic locations. In addition, applications in all topics relevant to the broad mission of NIH are welcome.
New Innovator Award: Supports exceptionally creative early career scientists proposing unusually innovative and high-impact projects. To read more about this award see the New Innovator Award website. Applications are due by August 18, 2023.
Transformative Research Award: Supports individuals or teams proposing unusually innovative research projects that are inherently risky and untested but have the potential to create or overturn fundamental paradigms. To read more about this award see the Transformative Research Award website. Applications are due by September 1, 2023.
Early Independence Award: Enables outstanding junior scientists with the intellect, scientific creativity, drive, and maturity to bypass the traditional postdoctoral training period and launch an independent research career. Applicants must have recently completed or will soon complete their doctoral degree or clinical training and have the support and guarantee of an independent research position from a host institution. To read more about this award see the Early Independence Award website. Applications are due by September 6, 2023.
For more information about NIH and its programs, click the button below.
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Reminder SOM Bridge Funding Program
Applications are due by May 29
Faculty in the School of Medicine are invited to apply for the 2023 summer cycle of Bridge Funding. The Bridge Funding program provides up to 12 months of support for full-time faculty members, with independent research programs, who are experiencing a temporary loss of significant funding.
The program is intended to support applicants who face a funding gap between two extramural research grants (usually R01 or equivalent). Typically, applicants have been unsuccessful in a recent attempt to renew or replace a federal grant but are likely to be funded upon submission of a revised application, based on scores and reviewers’ comments. Applicants must demonstrate that their research program is jeopardized due to lack of extramural funding, that they have one or more rounds of well-scored but unfunded federal applications, and that they will have exhausted all available discretionary or start-up funds within one year of applying for bridge funding.
To read more about eligibility criteria and application instructions, click here. For questions, please contact SOMbridgefunding@ucsf.edu.
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EXTRAMURAL RTW Charitable Foundation
Letters of intent are due by May 31
The RTW Charitable Foundation has issued a request for applications for its Research Grant program. The mission of the RTW Charitable Foundation is to power rare-disease research, medical innovation, and humanitarian collaborations to improve the health of underserved communities. The focus of its research grants is to support work aimed at developing therapeutics for ultrarare diseases.
2023 grants will provide up to $150,000 for one year to support translational projects that bridge the gap between proof-of-concept studies in animal models and preclinical safety/toxicology studies. The request for proposals is open to:
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Diseases that affect fewer than 2,000 patients worldwide (monogenetic, life-threatening conditions affecting fewer than 300 patients worldwide preferred)
- Diseases for which no commercial drug-development programs exist
- Projects in any therapeutic area
- Projects that involve any clinically validated therapeutic modality (gene-replacement and antisense oligonucleotide-based therapies preferred)
- Projects for which there is evidence that the proposed therapeutic modality works in an animal model (or in another suitable system)
To read more about eligibility criteria and application instructions, click here. Please notify Jennifer Schmidt to announcing your decision to apply and then follow application instructions in RFP.
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Reminder UCSF AIDS Research Institute (ARI) Call for Bold, New Ideas in HIV Research
Applications are due by June 2
The UCSF AIDS Research Institute (ARI) is calling for applications from investigators who need to generate data for bold new research ideas, that will lead to new and high-impact avenues of investigation in HIV research.
The award amount is up to $220,000 total and can be spent over a period of one to two years. UCSF faculty in any series are welcome to apply.
To read more about eligibility criteria and application instructions, click here. To apply, email your applications as a single PDF file to ari2@ucsf.edu. For questions, please contact Lauren Sterling.
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Reminder Extramural Harrington Discovery Institute Harrington Scholar-Innovator Award
Letter of intent submissions are due by June 5
The Harrington Discovery Institute is committed to supporting the work of physician-scientists. The flagship Harrington Scholar-Innovator program recognizes physician-scientists whose research has the potential to advance the standard of care. Successful applicants will receive a $100,000 guaranteed grant award, drug and business development support from Harrington's therapeutics development advisors, an opportunity to compete for an acceleration fund up to $300,000 and an opportunity to qualify for investment funds typically up to $2 million. Applicants must have an MD or MD/PhD.
To read more about eligibility criteria and application instructions, click here. Letter of intent submission deadline is June 5, 2023. Letter of Intent guidelines, including information needed and word counts, can be found here. To submit your LOI, go to our grant system and create an account. The full application deadline for those invited is August 7, 2023.
For questions, please contact Questions@HarringtonDiscovery.org.
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Extramural Research!America Call for Entries for Discovery | Innovation | Health Prize
Letter of intent submissions are due by June 15
Research!America’s 2023 Discovery | Innovation | Health Prize will recognize and provide support for a researcher or clinician with a bold vision for progress against pandemic threats. The $200,000 prize, generously supported by Pfizer, will be awarded in Washington, DC, in September 2023.
Competitive applicants are those who have contributed in important ways to progress against COVID-19 or whose work shows tremendous potential in addressing future pandemics. Applications are welcome from any of these fields or combination of fields: Biology, Chemistry, Life Sciences, Medicine, or Technology (such as AI or Data Science).
Applications will be reviewed by an independent jury chaired by Victor Dzau, MD, President of the National Academy of Medicine, and a Research!America Board member. Applications are welcome from individuals affiliated with a U.S.-based organization (e.g., academic research institution, academic medical center, independent research organization, non-profit organization, or for-profit company), including U.S.-global partnerships.
For questions, please contact Tim Haynes.
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UCSF Nutrition and Obesity Research Center (NORC) Pilot and Feasibility Award
Applications are due by July 1
The Nutrition Obesity Research Center (NORC) at UCSF is sponsoring an open Request for Applications (RFA) for Pilot and Feasibility Grants, which provide funding for investigators to pursue novel and promising ideas broadly relevant to nutrition, obesity, and metabolism research. The NORC Pilot and Feasibility Program is funded through a Center grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to facilitate the engagement of junior faculty and encourage new directions in NORC related research, regardless of a laboratory’s historical research focus.
Pilot funding of up to $50,000 per application is available for a period of 12 months from the time of award.
Preference will be given to Junior Faculty engaged in research broadly relevant to nutrition, obesity, and metabolism, who do not yet have NIH R01 funding (K awardees are eligible to apply). NIH review criteria (Significance, Investigators, Innovation, Approach, Environment) will be used.
To apply, email your applications as a single PDF file to Myra Gloria. For questions, please contact Myra Gloria or Brian Feldman.
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If you'd like to contribute to future newsletters, please send your items to Ilona Paredes.
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ReSearch ReSource Newsletter
The Office of Research delivers a monthly communication of news and resources dedicated to the research enterprise, a helpful companion to DOM Research News! Read the newsletter here.
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Resources for Space Planning Updates
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Copyright © 2023, University of California, San Francisco, All rights reserved.
Please send comments, suggestions and questions to:
Diane Havlir, MD, Associate Chair for Clinical Research (diane.havlir@ucsf.edu)
David Erle, MD, Associate Chair for Biomedical Research (david.erle@ucsf.edu)
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