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The RNA Transcript, April 10th 2023

Seminars

U-M RNA Innovation Seminar

Dissect enhancer architecture and map regulatory genomic landscape across diverse cell and tissue types through nascent transcriptome studies.


Haiyuan Yu, Ph.D

Professor

Department of Biological Statistics & Computational Biology

Weill Institute for Cell & Molecular Biology

Cornell University


TODAY, April 10, 2023

4:00 - 5:00 PM

ABC Seminar Room BSRB, Zoom

Biophysics Innovation Seminar

Engineering Automated Solution to Address Scientific Challenges


Joseph Lomino, Ph.D.

Process Development Fellow

Moderna


Friday, April 14, 2023

12:00 - 1:30 PM

1640 Chemistry

U-M RNA Innovation Seminar

RNA Synthetic Biology: Towards an Era of RNA Design for Biology & Global Health


Julius B. Lucks Ph.D.

Professor

Department of Chemical & Biological Engineering

Northwestern University


Monday, April 17, 2023

4:00 - 5:00 PM

ABC Seminar Room BSRB, Zoom

RNA Collaborative Seminar

Bay Area RNA Club (BARC)


Genomic expression cassettes drive unexpected RNAs and off-target effects

Speaker: Gloria Brar, Ph.D.


Progress in RNA 3D modeling?

Speaker: Rhiju Das, Ph.D.


Moderator: Stefan Oberlin, Ph.D.


Wednesday, April 26, 2023.

4:00 PM

Zoom.

RNA SOCIETY

Lexogen RNA Expertise Blog Series

We are happy to introduce you to the LEXOGEN RNA EXPERTISE blog series, in which we will talk about various topics from the world of RNA and RNA-Seq, focusing on best practices, exciting applications, and more. 


Inspired by the RNA journal's April 2023 special edition, we dedicate our newest blog post to RNA therapeutics. 


RNA Therapeutics: The Future is Bright


RNA therapeutics are a rapidly expanding category of drugs based on RNA molecules aimed at treating or preventing diseases. Recent clinical success and primarily the breakthrough of a series of fast-tracked and effective messenger RNA (mRNA)-based vaccines helping to conquer the COVID-19 pandemic did not only make “RNA” a household name but also reignited and propelled research interest in RNA therapeutics.


This blog article will discuss the advantages of RNA therapeutics, concepts, and modes of action of different classes of RNA-based therapeutics. We will also give a glimpse into the RNA therapeutics currently being evaluated in clinical trials or having received approval.

RNA Collaborative Lighting Talk Workshop & Competition

Are you passionate about your research? Want to share your love of science with the world? Need help with presentation skills? Join the RNA Collaborative Lightning Talk workshop!


You will learn how to use storytelling to present your ideas and connect with your audience. Never given a presentation before. Join us in learning best practices! Given plenty of talks? Join us for new techniques and to sharpen your skills!


Following the workshop, participants will be ready to make a 5-minute lightning talk to submit to our YouTube channel (https://www.youtube.com/channel/UC7QawzQsUqhgIqjKGTny41A). Videos will be judged by a panel of experts and the winners will receive a prize. Prizes include a one-year membership to the RNA Society and feature on our YouTube and social media channels. All participants will receive a certificate of recognition.


Watch last year's winners here: https://youtube.com/playlist?list=PLOKLGds2b7PbGJ7XPsymYeT0dWAkRa-fs


Applications will be accepted until April 17, 2023 –

Apply here: https://forms.office.com/r/2ZmHmm9eSY


The workshop will be held via Zoom on Monday, April 24, 2023.

Time TBD.


For more information contact Dr Laura Keffer-Wilkes at kefferwilkesl@uleth.ca

Alberta RNA Research and Training Institute, University of Lethbridge

https://www.ulethbridge.ca/research/centres-institutes/alberta-rna-research-and-training-institute

28th Annual Meeting of the RNA Society - May 30th thru June 4th

RNA 2023 - the 28th Annual Meeting of the RNA Society - will be held at the Suntec Convention Center in downtown Singapore from May 30th - June 4th. 

 

Registration is now open

 

Look forward to seeing you there.

Job Postings

University of Washington - Postdoctoral Positions

POSTDOCTORAL POSITIONS AVAILABLE

Mammalian Architectural RNAs in Health and Disease; Novel Technology Development, Shechner Lab, University of Washington.

 

Qualifications: Candidates must possess a Ph.D. or equivalent degree in Molecular Biology, Biochemistry, Genomics, Chemical Biology, or related fields, and must have fewer than five years postdoctoral experience. They must have strong communication skills and publications that indicate a track record of previous accomplishments. Expertise in RNA biology, chromatin biology and/or genomics technology development is preferred but not required. Candidates with prior training in RNA-FISH and/or bioinformatics analysis (e.g. Proteomics, RNA- and ChIP-Seq) are especially welcome. Candidates from traditionally underrepresented cultural, ethnic, religious, gender or socioeconomic groups are particularly encouraged to apply.


Interested applicants should send a cover letter, curriculum vitae, and the contact information for three references to David Shechner (shechner@uw.edu). Come join our team of plucky RNA Nerds!

Meetings

2023 NCI RNA Biology Symposium April 27 - 28 2

RNA biology has emerged as one of the most influential areas in modern biology and biomedicine. The discovery of new classes of RNAs and their functions in a wide spectrum of biological processes has revolutionized molecular biology and has profound implications for clinical sciences. Key areas include the elucidation of RNA biogenesis and structure, the identification of functions for various classes of RNAs, the roles of RNA in disease and the emergence of RNA-based-and RNA-targeted therapies.

 

The symposium offers the opportunity to learn more about the current status of RNA biology in development and disease and share research with leading figures in the field and discuss the use and implications of these advances for clinical applications.


We hope you join us for the 2023 NCI RNA Biology symposium!


Registration is free but is required to attend. There will be no onsite registration. 


For conference-related questions, please contact ccrconferences@mail.nih.gov.


April 27-28, 2023

National Institutes of Health 9000 Rockville Pike Bethesda, Maryland 20892

Building 45 Natcher Auditorium

2023 RiboClub Annual Meeting - September 24 - 28

The RiboClub Annual Meeting aims at encouraging the exchange of ideas and stimulates collaborations between RNA biologists around the world. The meeting covers different topics related to the chemistry, structure and biology of RNA with emphasis on upcoming and debatable biological questions. In addition, every year the RiboClub puts the focus on a local or regional RNA group to highlight their efforts and introduce them to the international community.

The meeting format provides principal investigators the opportunity to present their point of views on the current state of knowledge and ignite the curiosity of young scientists. The meeting size and its format give ample opportunity for discussions and interactions, so bring your thinking hat to uncover the next big idea.

Registration fees are subsidized to encourage the participation of students and upcoming researchers. All laboratory members are invited to attend, listen to the presentations of leading scientists and participate in poster competition.


Annual Meeting September 24-28, 2023

Chéribourg Hotel, Orford, Quebec, Canada


Register by: June 30th, 2023

More Inforamtion :www.riboclub.org

Questions: riboclub@riboclub.org

Our members' publications are available through Altmetrics. Queries are currently available: CRISPR, microRNA, molecule, RNA, RNA therapeutics, transcriptome, and translation.


Below are recent highlights.


Mandal, S., Khanna, K., Johnson-Buck, A., & Walter, N. G. (2022). A guide to accelerated direct digital counting of single nucleic acid molecules by FRET-based intramolecular kinetic fingerprinting. Methods (San Diego, Calif.)197, 63–73. Highlighted in NCI's Epidemiology & Genomics Research Program (EGRP) https://doi.org/10.1016/j.ymeth.2021.06.014

Wang, E. T., Freudenreich, C. H., Gromak, N., Jain, A., Todd, P. K., & Nagai, Y. (2023). What repeat expansion disorders can teach us about the Central Dogma. Molecular cell, 83(3), 324–329. https://doi.org/10.1016/j.molcel.2022.12.017

Stephen V. Carney, Kaushik Banerjee, Anzar Mujeeb, Brandon Zhu, Santiago Haase, Maria Luisa Varela, Padma Kadiyala, Claire E. Tronrud, Ziwen Zhu, Devarshi Mukherji, Preethi Gorla, Yilun Sun, Rebecca Tagett, Felipe J. Núñez, Maowu Luo, Weibo Luo, Mats Ljungman, Yayuan Liu, Ziyun Xia, Anna Schwendeman, Tingting Qin, Maureen A. Sartor, Joseph F. Costello, Daniel P. Cahill, Pedro R. Lowenstein, Maria G. Castro; Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance. Clin Cancer Res 2023; https://doi.org/10.1158/1078-0432.CCR-22-1896

To share your news and comments, please contact rna-communications@umich.edu

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