Cores Newsletter October 2023

Dr. Blake Meyers Takes the Helm as Director of UC Davis Genome Center

Welcome Dr. Blake Meyers, the incoming Director and Novozymes Chair in Genomics at UC Davis Genome Center. With a stellar background in plant RNA biology and genomics, his leadership promises to chart new frontiers in genomics research, benefiting both academia and society.

Reviving the Pacific Northwest Mint Industry

UC Davis Genome Center's Isabelle Henry and her team are at the forefront of this battle, working to develop verticillium-resistant Black Mitcham peppermint varieties while preserving the cherished mint flavors. Discover how their groundbreaking research offers hope for a thriving Pacific Northwest mint industry.

Proteomics Research Unveils Immune Defenses of Newborn Foals

Researchers, including Brett Phinney, Director of the UC Davis Proteomics Core, have found that newborn foals have lower levels of immune-related proteins in their lung lavage fluid compared to older foals and adult horses. This particularly affects proteins associated with antibacterial function. This reduced protein abundance in newborns may make them more susceptible to lung infections, as reported in PLOS ONE. The study paves the way for further investigation into the specific roles of these proteins in protecting neonatal lungs, offering valuable insights into equine health.

UPCOMING COURSES

Bits & Bites #06: Mass Spectrometry for Metabolomics

Oct 5, 2023 @ 9:00am - 12:00pm

In this short course, we will cover the fundamental principles of MS, including the different sample introduction types, ionization techniques, and mass analyzer varieties, and how they are used in metabolomics.

Introduction to R for Bioinformatics

Oct 30 - Nov 3, 2023 @ 2:00pm - 5:00pm

This three-part online workshop will give you a good base for analysis in bioinformatics using R. The R programming language is used for analyzing data in RNA-Seq experiments, single cell experiments, microbial community analysis, and more.

Bits & Bites #07: Introduction to Metaboanalyst

Nov 2, 2023 @ 9:00am - 12:00pm

In this short course, we will cover how to use MetaboAnalyst 5.0, a comprehensive platform dedicated to metabolomics data analysis.

Bits & Bites #08: Tips & Tricks of GC-MS in Metabolomics

Nov 16, 2023 @ 9:00am - 12:00pm

In this short course, we discuss the fundamentals of GC-MS, tips for best practices, and aspects of instrumentation, and demonstrate data processing and use of databases.

Introduction to Python for Bioinformatics

Dec 4 - Dec 8, 2023 @ 2:00pm - 5:00pm

Enhance your bioinformatics knowledge with this five-part online workshop in Introduction to Python. Python is a programming language that is used widely in the creation of many bioinformatics software.

Bits & Bites #09 Metabolomics for Epidemiologists

Dec 7, 2023 @ 9:00am - 12:00pm

This short course to provide an overview of metabolomics including realistic goals and considerations for study designs, and metabolite coverage from commercial providers versus core facilities.

More Courses

MESSAGE FROM THE CORE

Proteomics Core

Rapid Protein Quantification: We can now quantify over 5,000 proteins in just 11 minutes, requiring only 300-400 ng's of peptides from a well-prepared sample.

Automated Protein Digestion: Our state-of-the-art DNATech core's King Fisher Magnetic Particle processor allows us to automate protein digestion and phosphorylation enrichment on magnetic beads, streamlining the process.

Expanded Protein Quantification in Plasma: We've introduced two new methods to enhance protein quantification in plasma:

A simple and cost-effective approach for quantifying over 600 proteins from just 20 μl of plasma (from any species). For more information, click here.
A protocol that results in a remarkable ∼20-fold enrichment of known EV markers and ∼95% depletion of common plasma proteins. For more information, click here.

Amino Acid Analysis: We offer comprehensive amino acid analysis using our new Hitachi LC8080 AminoSAAYA Analyzer:

Protein Hydrolysates (PH): Quantification of 20 amino acids.
Physiological Fluids (PF): Quantification of over 60 amino acids.

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