UC Davis
West Coast Metabolomics Center
CASMI (Critical Assessment of Small Molecule Identification) contest 2022 is in full swing!

In untargeted assays, approximately 80% of all MS/MS spectra remain unidentified. Yet, the last CASMI contest was performed five years ago. As molecules of former CASMI contests are now well known, new datasets must be provided for testing compound ID strategies in 2022. The UC Davis West Coast Metabolomics Center is spearheading such a workshop to take place for the Metabolomics Society 2022 Conference in Valencia, Spain.

There's still time to participate! For more detailed information, rules, and link to download data check out our website: https://fiehnlab.ucdavis.edu/casmi
Contact Information: Arpana Vaniya, avaniya@ucdavis.edu

We are hiring! Open position as Technical Director of the WCMC core.
The Genome Center at the University of California, Davis invites applications from qualified candidates for the position of Technical Director of the UC Davis West Coast Metabolomics Center (WCMC). If interested, please see the details and apply here.

When: August 22 - September 2, 2022
Where: Hybrid (UC Davis Genome Center + Online)
 
The course will include:
  1. Study design, including pitfall analysis and hidden biases in studies from microbial, plant, mouse, and human cohort research
  2. Sample preparation and quality control
  3. Detailed discussions of standard operating procedures for GC-MS and LC-MS data acquisitions
  4. Targeted metabolomics, including monitoring charts and use of isotope-labeled internal standards
  5. Untargeted data processing and exercises on MS-DIAL software 
  6. Hands-on exercises on the identification of unknowns by cheminformatics software workflows (incl. MS-FINDER, CFM-ID, and various databases and small software routines)
  7. Data normalization and transformation with and without internal standards and quality controls
  8. Multivariate and univariate statistics 
  9. Pathway mapping
The next Bits & BItes are great for anyone who wants to gain a deeper insight into Bayesian statistics in Metabolomics, they'll be held on the following dates:

  • May 5, 2022: Introduction to Bayesian statistics in Metabolomics with Dr. Christopher Brydges, UC Davis
If you have any questions feel free to contact us!
Email: Jeannette Martins jmartins@ucdavis.edu
You can revisit any online lectures from our past speakers on the WCMC YouTube channel.
Fresh off the press
Brydges, C. R., et al. "Metabolomic and inflammatory signatures of symptom dimensions in major depression." Brain, Behavior, and Immunity 102 (2022): 42-52.

DeFelice, B. C., et al. "Polyamine Metabolites as Biomarkers in Head and Neck Cancer Biofluids." Diagnostics 12.4 (2022): 797.